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Elsevier

Academic Press

  • Nano-Pharmacokinetics and Theranostics

    Advancing Cancer Therapy
    • 1st Edition
    • Nanasaheb D. Thorat + 1 more
    • English
    Nano-Pharmacokinetic... and Theranostics: Advancing Cancer Therapy addresses from a comprehensive and multidisciplinary approach the translational aspects and clinical perspectives of nano-pharmacokinetic... using cancer as a model disease. Nano-pharmacokinetic... is emerging as an important sub discipline of nanoscience and medical sciences because of the increasing safety issues of nanosystems on living organisms. This book reports the dynamics of nanosystems in living organisms for better understanding of nanotoxicity, pharmacology, biochemistry, physiology and medicine perspectives. It further examines current progress of state-of-the art pharmacokinetics mechanisms, which will be of great help to develop more clinical-oriented nanosystems with a wide safety margin. The book is divided into three sections: the first section focuses on the concept of pharmacokinetics with state-of-the-art Nano-Pharmacokinetic... (NPK). The second section looks at the engineering of nanoparticles and pharmacokinetics clinical development. The final section focuses on Nano-Pharmacokinetic... and Theranostics, elaborating the basic question of how pharmacokinetics of nanomaterials relate to their end applications such as cancer therapy. Nano-Pharmacokinetic... and Theranostics: Advancing Cancer Therapy will be useful to researchers in the field of nanoparticle based targeted drug delivery including pharmaceutical scientists, material scientists, chemists, nanotechnologists, biomedical scientists, and clinicians.

  • Leveraging Artificial Intelligence in Global Epidemics

    • 1st Edition
    • Le Gruenwald + 2 more
    • English
    Leveraging Artificial Intelligence in Global Epidemics provides readers with a detailed technical description of the role Artificial Intelligence plays in various stages of a disease outbreak, using COVID-19 as a case study. In the fight against epidemics, medical staff are on the front line; but behind the lines the battle is fought by researchers, and data scientists. Artificial Intelligence has been helping researchers with computer modeling and simulation for predictions about disease progression, the overall economic situation, tax incomes and population development. In the same manner, AI can prepare researchers for any emergency situation by backing the medical science. Artificial Intelligence plays a key and cutting-edge role in the preparedness for and dealing with the outbreak of global epidemics. It can help researchers analyze global data about known viruses to predict the patterns of the next pandemic and the impacts it will have. Not only prediction, AI plays an increasingly important role in assessing readiness, early detection, identification of patients, generating recommendations, situation awareness and more. It is up to the right input and the innovative ways by humans to leverage what AI can do. As COVID-19 has grabbed the world and its economy today, an analysis of the COVID-19 outbreak and the global responses and analytics will pay a long way in preparing humanity for such future situations.

  • Modern Methods for Affordable Clinical Gait Analysis

    Theories and Applications in Healthcare Systems
    • 1st Edition
    • Anup Nandy + 3 more
    • English
    Modern Methods for Affordable Clinical Gait Analysis: Theories and Applications in Healthcare Systems is a handbook of techniques, tools and procedures for the study and improvement of human gait. It gives a concise description of clinical gait analysis, especially gait abnormality detection problems and therapeutic interventions using inexpensive devices. A brief demonstration on validation testing of these devices for its clinical applicability is also presented. Content coverage also includes step-by-step processing of the data acquired from these devices. Future perspectives of low-cost clinical gait assessment systems are explored. This book bridges the gap between engineering and biomedical fields as it diagnoses and monitors neuro-musculoskeleta... abnormalities using the latest technologies. The authors discuss how early detection technology allows us to take precautionary measures, in order to delay the degeneration process, through development of a clinical gait analysis tool. One unique feature of this book is that it pays significant attention to the challenges of conducting gait analysis in developing countries with limited resources. This reference will guide you through setting up a low-cost gait analysis lab. It explores the relationship between vision-based pathological gait detection, the design of tools for gait diagnosis and therapeutic interventions.

  • Handbook of Hormones

    Comparative Endocrinology for Basic and Clinical Research
    • 2nd Edition
    • Hironori Ando + 2 more
    • English
    Handbook of Hormones: Comparative Endocrinology for Basic and Clinical Research, Second Edition presents a catalog of fundamental information on the structure and function of hormones from basic biology to clinical use, offering a rapid way to obtain specific facts about the chemical and molecular characteristics of hormones, their receptors, signaling pathways, and the biological activities they regulate. The book's stellar editorial board, affiliated with the Japan Society for Comparative Endocrinology, brings together authors that present a compelling structure of each hormone with a consistent presentation that provides a primer surrounding the plethora of hormones that now exist. Comparative endocrinology continues to rapidly expand and new information about hormones is being produced almost daily, making it important to stay up-to-date. Hormone, paracrine, and autocrine factors have been identified as key players in a range of different systems, including immune, musculoskeletal and cardiovascular. Frontiers between disciplines are being blurred and many scientists in fields other than endocrinology are interested in hormones. Scientists now have the unprecedented opportunity to look from invertebrates to vertebrate and identify novel regulatory factors and understand their function and how they determine an organism’s physiology and survival.

  • Escaping from Bad Decisions

    A Behavioral Decision-Theoretic Perspective
    • 1st Edition
    • Kazuhisa Takemura
    • English
    Escaping from Bad Decisions presents a modern conceptual and mathematical framework of the decision-making process. By interpreting ordinal utility theory as normative analysis examined in view of rationality, it shows how decision-making under certainty, risk, and uncertainty can be better understood. It provides a critical examination of psychological models in multi-attribute decision-making, and evaluates the constitutive elements of "good" and "bad" decisions. Multi-attribute decision-making is analysed descriptively, based on the psychological model of decision-making and computer simulations of decision strategies. Finally, prescriptive examinations of multi-attribute decision-making are performed, supporting the argument that decision-making from a pluralistic perspective creates results that can help "escape" from bad decisions. This book will be of particular interest to graduate students and early career researchers in economics, decision-theory, behavioral economics, experimental economics, psychology, cognitive sciences, and decision neurosciences.

  • Synthetic and Enzymatic Modifications of the Peptide Backbone

    • 1st Edition
    • Volume 656
    • English
    Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Ultrawide Bandgap Semiconductors

    • 1st Edition
    • Volume 107
    • English
    Ultrawide Bandgap Semiconductors, Volume 107 in the Semiconductors and Semimetals series, highlights the latest breakthrough in fundamental science and technology development of ultrawide bandgap (UWBG) semiconductor materials and devices based on gallium oxide, aluminium nitride, boron nitride, and diamond. It includes important topics on the materials growth, characterization, and device applications of UWBG materials, where electronic, photonic, thermal and quantum properties are all thoroughly explored.

  • Omega-3 Delivery Systems

    Production, Physical Characterization and Oxidative Stability
    • 1st Edition
    • Pedro J. García-Moreno + 3 more
    • English
    Omega-3 Delivery Systems: Production, Physical Characterization and Oxidative Stability offers the most recent updates for developing, characterizing, and stabilizing both traditional and novel omega-3 delivery systems, including their final incorporation into food matrices and physicochemical changes during digestion. The book brings chapters on novel omega-3 delivery systems (e.g., high-fat emulsions, Pickering emulsions, electrosprayed capsules, and solid lipid nanoparticles), the application of advanced techniques to evaluate physical and oxidative stabilities (e.g., SAXS, SANS, ESR, and super-resolution fluorescence microscopy), and new developments of food enrichment and physicochemical changes during digestion. The book provides a unique multidisciplinary and multisectoral approach, i.e., featuring authors from industry and academy. Long chain omega-3 polyunsaturated fatty acids (PUFA) present numerous health benefits; however, the consumption of natural products rich in omega-3 PUFA (e.g., fish, krill, and algae) is not enough to reach the daily-recommended values. Therefore, the food industry is highly interested in producing omega-3 fortified foods.

  • Advances in Food and Nutrition Research

    • 1st Edition
    • Volume 97
    • Fidel Toldra
    • English
    Advances in Food and Nutrition Research, Volume 97 provides interesting chapters written by an international board of authors. The topics covered in this book include the problematics of bacteriophages in dairy plants and methods for their monitorization and control, the obtention of antioxidant and antimicrobial compounds from sustainable sources and their application in meat and seafood products, the challenges and opportunities for vibrational spectroscopy to measure composition, and functional properties of foods, the physiological activity of bioactive peptides obtained from meat and meat by-products, the use of plant and marine-based polysaccharides for nano-encapsulation and their applications in food industry, the effects of early life stress on eating behavior and metabolism considering different factors that control appetite, the nutritional aspects of seafood and its health benefits, the use of Colocasia esculenta (L.) Schott and Xanthosoma sagittifolium (L.) Schott powder as a valid option for the nutritional and technological improvement of food products, and much more. The series provides the latest advances on the identification and characterization of emerging bioactive compounds with putative health benefits, and other functional compounds of relevance in foods as well as up-to-date information on food science, including raw materials, production, processing, distribution and consumption.

  • Monitoring Vesicular Trafficking in Cellular Responses to Stress - Part B

    • 1st Edition
    • Volume 165
    • English
    Monitoring Vesicular Trafficking in Cellular Responses to Stress - Part B, Volume 165 in the Methods in Cell Biology series, highlights new advances in the field, with this new release presenting coverage of different topics, including A novel tool for detecting lysosomal membrane permeabilization by high-throughput fluorescence microscopy, Exploring selective autophagy in Drosophila, Assessment of EGFP-Q74 degradation for the measurement of autophagic flux, Multimodal assessment of autophagy in mammalian cells with a novel, LC3-based tandem reporter, Multiplex quantification of autophagic flux by imaging flow cytometry, Monitoring autophagic flux in Caenorhabditis elegans using p62/SQST-1 reporters, High throughput screening for autophagy, and much more.

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