Skip to main content

Handbook of Hormones

Comparative Endocrinology for Basic and Clinical Research

  • 2nd Edition - July 27, 2021
  • Latest edition
  • Editors: Hironori Ando, Kazuyoshi Ukena, Shinji Nagata
  • Language: English

Handbook of Hormones: Comparative Endocrinology for Basic and Clinical Research, Second Edition presents a catalog of fundamental information on the structure and function… Read more

Description

Handbook of Hormones: Comparative Endocrinology for Basic and Clinical Research, Second Edition presents a catalog of fundamental information on the structure and function of hormones from basic biology to clinical use, offering a rapid way to obtain specific facts about the chemical and molecular characteristics of hormones, their receptors, signaling pathways, and the biological activities they regulate. The book's stellar editorial board, affiliated with the Japan Society for Comparative Endocrinology, brings together authors that present a compelling structure of each hormone with a consistent presentation that provides a primer surrounding the plethora of hormones that now exist.

Comparative endocrinology continues to rapidly expand and new information about hormones is being produced almost daily, making it important to stay up-to-date. Hormone, paracrine, and autocrine factors have been identified as key players in a range of different systems, including immune, musculoskeletal and cardiovascular. Frontiers between disciplines are being blurred and many scientists in fields other than endocrinology are interested in hormones. Scientists now have the unprecedented opportunity to look from invertebrates to vertebrate and identify novel regulatory factors and understand their function and how they determine an organism’s physiology and survival.

Key features

  • Presents hormones in groups according to their origin so that readers can easily understand their inter-relation
  • Includes 47 new hormones, such as neuropeptides, cytokines, growth hormones, biogenic amines and amino acids that are important for cell to cell communication via endocrine, paracrine and neurotransmitter signaling
  • Summarizes the current knowledge of hormone evolution based on comparative genome resources, such as synteny, genome sequence and comprehensive phylogeny
  • Covers a wide range of information on hormones, from basic information on structure and function across vertebrate and invertebrate phyla to clinical applications
  • Collates key information on 259 hormones and 47 groups/families

Readership

Medical and biological researchers in endocrinology, comparative endocrinology, immunology, neurobiology, pharmacology, along with various clinical medicine such as pathology, cardiovascular biology, gastroenterology

Table of contents

PART I PEPTIDES AND PROTEINS IN VERTEBRATES
Molecule Evolution of Peptide and Protein Hormones in Vertebrates
Section I.1. Neuropeptides
Chapter 1. RFamide Peptide Family

1A. Gonadotropin-Inhibitory Hormone

1B. Kisspeptin

1C. PQRFamide Peptide

1D. Pyroglutamylated RFamide Peptide

1E. Prolactin-Releasing Peptide
Chapter 2. Corticotropin-Releasing Hormone Family

2A. Corticotropin-Releasing Hormone

2B. Urotensin-I

2C. Urocortins

2D. Sauvagine
Chapter 3. Gonadotropin-Releasing Hormone
Chapter 4. Thyrotropin-Releasing Hormone
Chapter 5. Somatostatin/Neuronostatin
Chapter 6. Neurohypophysial hormone family

6A. Vasopressin

6B. Vasotocin

6C. Oxytocin

6D. Non-Mammalian Oxytocin Family Peptides
Chapter 7. Opioid Peptide Family

7A. Enkephalin

7B. Dynorphin/α-Neo-endorphin

7C. Nociceptin/Orphanin FQ/Nocistatin

7D. Endomorphin

7E. Dermorphin
Chapter 8. Agouti Family

8A. Agouti-Signaling Protein

8B. Agouti-Related Protein
Chapter 9. Tachykinin Family

9A. Substance P/Neurokinin A

9B. Neurokinin B
Chapter 10. Appetite-Regulating Peptides

10A. Melanin-Concentrating Hormone

10B. Orexin

10C. Cocaine- and Amphetamine-Regulated Transcript
Chapter 11. Urotensin II
Chapter 12. Neurotensin
Chapter 13. Neuromedin U/S /Precursor-related peptide
Chapter 14. Neuropeptide S
Chapter 15. Neuropeptide W
Chapter 16. Neuroendocrine Regulatory Peptide
Chapter 17. Neurosecretory peptide GL/GM
Chapter 18. Nesfatin-1
Chapter 19. Mexneurin
Chapter 20. Phoenixin

Section I.2. Adenohypophysial Hormones
Chapter 21. Glycoprotein Hormone Family

21A. Follicle-Stimulating Hormone

21B. Luteinizing Hormone

21C. Thyroid-Stimulating Hormone
Chapter 22. Growth Hormone/Prolactin Family

22A. Growth Hormone

22B. Prolactin

22C. Somatolactin
Chapter 23. Proopiomelanocortin Family

23A. Adrenocorticotropic Hormone

23B. Melanocyte-Stimulating Hormone

23C. Endorphin
Section I.3. Gastrointestinal Hormones
Chapter 24. Glucagon Family

24A. Glucagon

24B. Gastric Inhibitory Peptide

24C. Glucagon-Like Peptide-1

24D. Glucagon-Like Peptide-2
Chapter 25. Secretin (Pituitary Adenylate Cyclase-Activating Polypeptide) Family

25A. Secretin

25B. Growth Hormone-Releasing Hormone

25C. Pituitary Adenylate Cyclase-Activating Polypeptide

25D. Pituitary Adenylate Cyclase-Activating Polypeptide-Related Peptide

25E. Vasoactive Intestinal Peptide

25F. Peptide Histidine Isoleucine/Methionine
Chapter 26. Insulin Family

26A. Insulin

26B. Insulin-Like Growth Factor-I

26C. Insulin-Like Growth Factor-II

26D. Insulin-Like Growth Factor Binding Proteins

26E. Relaxins

26F. Insulin like 6/relaxin-like factor/relaxin-insulin-like factor-1
Chapter 27. Gastrin Family

27A. Gastrin

27B. Cholecystokinin

27C. Caerulein
Chapter 28. Ghrelin_Motilin Family

28A. Ghrelin

28B. Motilin

28C. Liver-expressed antimicrobial peptide 2
Chapter 29. Bombesin-Like Peptide Family

29A. Gastrin-Releasing Peptide

29B. Neuromedin B
Chapter 30. Guanylin Family

30A. Guanylin

30B. Uroguanylin
Chapter 31. Galanin Peptide Family

31A. Galanin

31B. Galanin-Like Peptide

31C. Alarin
Chapter 32. Neuropeptide Y Family

32A. Pancreatic Polypeptide

32B. Neuropeptide Y

32C. Peptide YY
Chapter 33. Chromogranin A/Pancreastatin
Chapter 34. Xenin
Section I.4. Parathyroid Gland, Ultimobranchial Gland, and Stannius Corpuscle Hormones
Chapter 35. Parathyroid Hormone Family

35A. Parathyroid Hormone

35B. Parathyroid Hormone-Related Protein

35C. Tuftelin-interacting protein 39
Chapter 36. Calcitonin/Calcitonin Gene-Related Peptide Family

36A. Calcitonin

36B. Calcitonin Gene-Related Peptide

36C. Calcitonin Receptor-Stimulating Peptide

36D. Adrenomedullin

36E. Adrenomedullin 2 and 5

36F. Amylin
Chapter 37. Stanniocalcin
I-5. Cytokines and Growth Factors
Chapter 38 Cytokines

38A Interleukins

38B Tumor necrosis factorα

38C Interferones
Chapter 39 Hematopoietic growth factors

39A Erythropoietin

39B Thrombopoietin

39C Granulocyte colony-stimulating factor
Chapter 40 Cell proliferation factors

40A Epidermal growth factor

40B Fibroblast growth factor

40C Platelet-derived growth factor

40D Hepatocyte growth factor

40E Transforming growth factor
Chapter 41 Neurotrophins

41A Nerve growth factor

41B Brain-derived neurotrophic factor

41C Neurotrophin-3
Section I.6. Other Peripheral Hormones
Chapter 42. Renin-Angiotensin System

42A. Renin

42B. Angiotensin II

42C. Other Angiotensins

42D. Angiotensin Converting Enzymes

42E. Vasoconstriction-inhibiting factor
Chapter 43. Kallikrein-Kinin System

43A. Kininogen

343B. Kallikrein

43C. Bradykinin
Chapter 44. Apelin
Chapter 45. ELABELA
Chapter 46. Natriuretic Peptide Family

46A. Atrial Natriuretic Peptide

46B. B-type Natriuretic Peptide

46C. C-type Natriuretic Peptides

46D. Ventricular Natriuretic Peptide
Chapter 47. Gonadal Hormones

47A. Inhibin

47B. Activin

47C. Follistatin

47D. Anti-Mullerian Hormone
Chapter 48. Adipocyte Hormones

48A. Leptin

48B. Adiponectin

48C. Acylation Stimulating Protein

48D. Resistin
Chapter 49. Endothelin
Chapter 50. Irisin
Chapter 51. Osteopontin
Chapter 52. Osteocrin
Chapter 53. Hepcidin/Liver-expressed antimicrobial peptide 1
Chapter 54. Salusin
Chapter 55. Adropin
Chapter 56. Lipocalin-2

PART II PEPTIDES AND PROTEINS IN INVERTEBRATES
Section II.1. Neuropeptides Related to Vertebrate Hormones
Chapter 57. Gonadotropin-Releasing Hormone-Like Peptide Family

57A. Protochordata Gonadotropin-Releasing Hormone

57B. Molluscan Gonadotropin-Releasing Hormone

57C. Echinoderm gonadotropin-releasing hormone
Chapter 58. Corticotropin-Releasing Factor-Like Peptide
Chapter 59. Oxytocin/Vasopressin Superfamily

59A. Lys-Conopressin

59B. Cephalotocin/Octopressin

59C. Annetocin

59D. Inotocin

59E. Nematocin

59F. Ci-Vasopressin
Chapter 60. Neuropeptide F
Chapter 61. Short Neuropeptide F
Chapter 62. RYamide
Chapter 63. Tachykinin-Like Peptide Family

63A. Protochordate Tachykinin

63B. Tachykinin-Related Peptides
Chapter 64. Insulin Superfamily

64A. Insect Insulin-Like Peptides

64B. Insect Insulin-Like Growth Factor-Like Peptides

64C. Molluscan Insulin-Related Peptides

64D. Androgenic Gland Hormone

64E. Relaxin-like Gonad-Stimulating Peptide
Chapter 65. Sulfakinin
Chapter 66. Cionin
Chapter 67. Ci-Galanin-Like Peptide
Chapter 68. Allatostatin-C
Chapter 69. Calcitonin-like Diuretic Hormone
Chapter 70. Ascidian calcitonin
Chapter 71. Amphioxus calcitonin family peptide
Chapter 72. Achinoderm calcitonin family peptide
Section II.2. Invertebrate-Unique Peptides
Subsection II.2.1 Regulation of Development and Metabolism
Chapter 73. FXPRLamide Peptide Family

73A. Diapause Hormone

73B. Pheromone Biosynthesis Activating Neuropeptide

73C. Pyrokinin
Chapter 74. Crustacean Hyperglycemic Hormone
Chapter 75. Ion Transport Peptide
Chapter 76. Prothoracicotropic Hormone
Chapter 77. Bursicon
Chapter 78. Allatotropin
Chapter 79. Allatostatin-A
Chapter 80. Adipokinetic Hormone
Chapter 81. Neuroparsin
Chapter 82. Ovary Maturating Parsin
Subsection II.2.2 Regulation of Myo/Cardio-Activities
Chapter 83. LF Peptides

83A. Head Activator

83B. Hym-323
Chapter 84. Invertebrate Kinins
Chapter 85. FMRFamides
Chapter 86. Myoinhibiting Peptide
Chapter 87. Myosuppressin
Chapter 88. Proctolin
Chapter 89. Orcokinins
Chapter 90. Crustacean Cardioactive Peptide
Chapter 91. Cardioacceleratory Peptide 2b
Chapter 92. Achatina Cardio-Excitatory Peptide-1
Chapter 93. Fulicins
Chapter 94. Buccalins
Chapter 95. Eisenia Inhibitory Pentapeptides
Chapter 96. GGNG Peptides

Subsection II.2.3 Regulation of Behaviors
Chapter 97. Eclosion Hormone
Chapter 98. Ecdysis Triggering Hormone
Chapter 99. Sex Peptide
Chapter 100. APWGamide
Chapter 101. SIFamide
Chapter 102. Egg-Laying Hormone
Subsection II.2.4 Other Hormones and Neuropeptides
Chapter 103. Growth Blocking Peptide
Chapter 104. Yamamarin
Chapter 105. CCHamide
Chapter 106. Corazonin
Chapter 107. Trypsin-Modulating Oostatic Factor
Chapter 108. Colloostatin
Chapter 109. Pigment Dispersing Hormone
Chapter 110. GLWamide
Chapter 111. Hym-176
Chapter 112. Hym-301
Chapter 113. Leech Osmoregulatory Factor
Chapter 114. Ciona YFV/L peptide

PART III LIPOPHILIC HORMONES IN VERTEBRATES
Chapter 115. Thyroid Hormones

115A. 3,30,5-Triiodothyronine

115B. Thyroxine

115C. Thyronamines
Chapter 116. Gonadal Steroids

116A. Progesterone

116B. 17,20β-Dihydroxy-4-pregnen-3-one

116C. 17,20β,21-Trihydroxy-4-pregnen-3-one

116D. Dehydroepiandrosterone

116E. Testosterone/Dihydrotestosterone

116F. 11-Ketotestosterone

116G. Estradiol-17β

116H. Estrone
Chapter 117. Corticosteroids

117A. Corticosterone

117B. 18-Hydroxycorticosterone

117C. 1α-Hydroxycorticosterone

117D. Cortisol

117E. Aldosterone
Chapter 118. Neurosteroids

118A. Pregnenolone Sulfate

118B. 7α-Hydroxypregnenolone

118C. Allopregnanolone
Chapter 119. Vitamin D Derivatives

119A. Calcitriol

119B. Cholecalciferol

PART IV LIPOPHILIC HORMONES IN INVERTEBRATES
Chapter 120. Ecdysteroids

120A. 20-Hydroxyecdysone
Chapter 121. Juvenile Hormone
Chapter 122. Methyl Farnesoate

PART V ENDOCRINE DISRUPTING CHEMICALS
Chapter 123. Endocrine Disruptors

123A. Nonylphenol

123B. Octylphenol

123C. Bisphenol A

123D. Dichlorodiphenyltrichloroethane

123E. 17α-Ethinylestradiol

123F. Equilin

123G. 2,3,7,8-Tetrachlorodibenzo-p-dioxin/Polychlorinated Biphenyls

123H. 1,1-Dichloro-2,2-bis(p-chlorophenyl)ethylene

123I. Vinclozolin

123J. Polybrominated Diphenyl Ether
Chapter 124. Anti-Thyroid Hormone Active Chemicals

124A. Tetrabromobisphenol A

124B. Perchlorate
PART VI Amines and Amino Acids
Chapter 125 Amines

125A Dopamine

125B Noradrenaline

125C Adrenaline

125D Octopamine

125E Serotonin

125F Melatonin

125G Histamine
Chapter 126 Amino Acids

126A Glutamic acid

126B Gamma -Aminobutyric acid

126C Glycine
Chapter 127 Acetylcholine

PART VII GASOTRANSMITTERS
Chapter 128. Gasotransmitter Family

128A. Nitric Oxide

128B. Carbon Monoxide

128C. Hydrogen Sulfide

Review quotes

"This second edition includes many newly identified hormones as well as introductory chapters introducing comparative endocrinology as it relates to the molecular evolution of hormones in vertebrates and invertebrates."—© Doody’s Review Service, 2021, Uzma N Syed, MDD, reviewer, expert opinion

Product details

  • Edition: 2
  • Latest edition
  • Published: July 29, 2021
  • Language: English

About the editors

HA

Hironori Ando

Sado Marine Biological Station, Faculty of Science, Niigata University, Niigata, Japan. His specific research interest involves neuroendocrine regulation of behavioral and physiological functions in diadromous migratory fish, such as salmonids and puffer fish.
Affiliations and expertise
Marine Biological Station, Sado Island Center for Ecological Sustainability, Niigata University, Japan

KU

Kazuyoshi Ukena

Graduate School of Integrated Arts and Sciences, Hiroshima University, Hiroshima, Japan. Professor Ukena discovered NPGL, a brain chemical that regulates hunger and fat storage in mammals, shows that hunger and energy consumption mechanisms are even more complex than we realized and has broad clinical and societal implications for the study and treatment of obesity and its associated diseases.
Affiliations and expertise
Graduate School of Integrated Sciences for Life, Hiroshima University, Japan

SN

Shinji Nagata

Graduate School of Frontier Science, The University of Tokyo, Chiba, Japan. His research interests incluces regulatory mechanisms of feeding behavior in insects at a molecular level. In the laboratory, they use insects to understand the underlying strategies used by animals to survive. A number of the techniques and devices required for such investigation are available for use, including the purification of biologically active compounds, protein and peptide purification, molecular cloning, intracellular signaling, and bioimaging.
Affiliations and expertise
Graduate School of Frontier Science, The University of Tokyo, Japan

View book on ScienceDirect

Read Handbook of Hormones on ScienceDirect