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Advanced Vaccination Technologies for Infectious and Chronic Diseases

A guide to Vaccinology

  • 1st Edition - March 25, 2024
  • Latest edition
  • Editors: Vasso Apostolopoulos, Lalitkumar K. Vora, Vivek P. Chavda
  • Language: English

Advanced Vaccination Technologies for Infectious and Chronic Diseases is a comprehensive guide that delves into the intricate details of vaccine design, development across vario… Read more

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Description

Advanced Vaccination Technologies for Infectious and Chronic Diseases is a comprehensive guide that delves into the intricate details of vaccine design, development across various platforms, and the path to commercialization. This book provides an introductory overview of vaccines, covering various types, developmental methodologies, delivery systems, adjuvants, immunization, and measurement of vaccine efficacy. It also showcases examples of vaccine research efforts targeting infectious diseases, autoimmune disorders, and cancer. The book concludes by exploring cutting-edge advances in proteogenomics, immunopeptidomics, and future vaccine technologies.
The primary objective of this book is to inform a broad scientific audience about the fundamental concepts underlying vaccine and immunology. Further, it serves as an invaluable reference for understanding the critical steps in the journey from discovery to regulatory processes for human clinical trials, addressing common misconceptions and presenting factual information about vaccinations. Advanced Vaccination Technologies for Infectious and Chronic Diseases is a requisite reference for occupational health professionals whose roles involve supervision of immunization programs such as those working within the National Health Service, some sectors of higher education, or the pharmaceutical industry. It also caters to those researchers engaged in vaccine development and all who want to learn the processes involved from laboratory research to final product.

Key features

  • Offers comprehensive coverage of different vaccine platforms and their development
  • Includes information on the regulatory perspective of vaccine development
  • Describes different delivery approaches for vaccinology
  • Explains the clinical development of vaccines along with novel platforms
  • Covers all recent developments of vaccine production technologies, new types of vaccines, and ongoing research that could prevent future pandemics

Readership

Graduates, post-graduates, researchers, scientists in the field of immunology, drug delivery, biology, engineering, medicine, pharmacuticals technology, medical professionals and other interdisciplinary fields of science and technology involved in developing vaccines

Table of contents

1: History of Vaccination

2: Vaccine Adjuvants and carriers

3: Conventional vaccination methods: Inactivated and Live attenuated vaccines

4: Subunit protein based Vaccines

5: Peptide based vaccines and altered peptide ligands: Multiple Sclerosis paving the way

6: Vector based vaccine delivery and associated immunity: Current Status and Way Forward

7: It’s all about the delivery: How to augment the efficiency of DNA vaccination

8: Plant-based biotechnological vaccines for emerging infectious diseases

9: Expression system and purification process for the vaccine production

10: Targeting dendritic cells for antigen delivery for vaccine design

11: Parenteral Vaccine delivery: from basic principles to new developments

12: Mucosal Vaccine delivery

13: Personalized vaccines, novel vaccination technologies and future prospects

14: The application of nanoparticle-based delivery systems in vaccine development

15: Preclinical and clinical development for vaccines and formulations

16: Regulatory processes involved in clinical trials and IPR around vaccine development

17: Vaccine safety, efficacy, and ethical considerations

18: Regulatory consideration and pathways for vaccine development

19: New approaches to vaccines for infectious diseases

20: New approaches to vaccines for cancer

21: New approaches to vaccines for autoimmunity

22: The fast-track development COVID-19 vaccines

23: Myths and Facts about Vaccination: Dispelling Myths and Misconceptions with Science

24: Proteogenomics and immunopeptidomics in the development of advanced vaccines

25: Future Vaccine Technologies

Product details

  • Edition: 1
  • Latest edition
  • Published: March 28, 2024
  • Language: English

About the editors

VA

Vasso Apostolopoulos

Professor Vasso Apostolopoulos is a Distinguished Professor at RMIT University, Australia. She received her PhD in immunology in 1995 from the University of Melbourne and the Advanced Certificate in Protein Crystallography from Birkbeck College, University of London. Professor Vasso Apostolopoulos is a world-renowned researcher who has been recognized with over 100 awards for the outstanding results of her research. She has published over 500 research publications, 8 books, and 33 book chapters, is a sought-after keynote speaker at conferences, is an inventor on 21 patents, and has over 22,000 citations.

Affiliations and expertise
Distinguished Professor, School of Health and Biomedical Sciences, RMIT University School of Health and Biomedical Sciences

LV

Lalitkumar K. Vora

Dr. Lalitkumar K. Vora is a Lecturer at the School of Pharmacy, Queen’s University, Belfast, and was included in Stanford's top 2% of world scientists list in 2023.

Affiliations and expertise
Lecturer, School of Pharmacy, Queen’s University, Belfast, UK

VC

Vivek P. Chavda

Vivek P. Chavda is an Assistant Professor (Selection Grade) in the Department of Pharmaceutics and Pharmaceutical Technology at L. M. College of Pharmacy, Ahmedabad, Gujarat, India. He earned Bachelor and Master of Pharmacy degrees and was a Gold Medallist at Gujarat Technological University. Before entering academia, he spent several years in the Biologics industry, contributing to R&D and regulatory filings for biologics. His scholarly output includes numerous peer‑reviewed articles, several books and book chapters, and ongoing writings in newsletters. His research spans the development of biologics processes and formulations, medical device development, nano diagnostics and noncarrier formulations, long-acting parenteral formulations, and nano vaccines. He also has patent assets in development and a record of industry-focused publications.

Affiliations and expertise
Assistant Professor, Department of Pharmaceutics and Pharmaceutical Technology, L M College of Pharmacy, Ahmedabad, Gujarat, India

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