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Books in Pharmaceutical sciences

Elsevier's Pharmaceutical Sciences collection helps pharmaceutical scientists striving to optimize drug design and improve healthcare outcomes by offering comprehensive coverage of every aspect of drug development, integrating disciplines like organic chemistry, biology, and biotechnology. Focused on safety, efficacy, and formulation design, it includes specialized fields such as Clinical Pharmacology and Translational Research, providing valuable insights into the latest advancements in drug discovery.

  • Medicines Safety and Pharmacovigilance

    Introduction, Concepts, and Applications
    • 1st Edition
    • Rabia Hussain
    • English
    Medicines Safety and Pharmacovigilance: Introduction, Concepts, and Applications provides a comprehensive guide for pharmaceutical professionals navigating the complex landscape of medicine safety and vigilance. Designed to support strategic decision-making, this reference draws on industry expertise to uphold the highest standards of patient care. The book addresses essential regulatory requirements, reporting obligations, and ethical considerations, offering practical guidance for implementing effective pharmacovigilance systems. Covering the latest technological advancements, it ensures readers are equipped to meet the modern challenges faced by healthcare and pharmaceutical sectors in monitoring the safety and efficacy of medicines for diverse populations worldwide.Beyond the foundational concepts, the book presents detailed insights into signal detection, risk management plans, and the real-world application of pharmacovigilance through case studies from both high- and low-middle-income countries. It examines the pivotal role of pharmacists and the importance of tailored approaches for special populations, while emphasizing effective communication of medicines safety.
  • Membrane Transporters and Drug Delivery

    A Comprehensive and Multidisciplinary Guide
    • 1st Edition
    • Elena Puris + 3 more
    • English
    Membrane Transporters and Drug Delivery: A Comprehensive and Multidisciplinary Guide is a comprehensive reference on the rapidly evolving field of membrane transporters and their role in drug delivery. The book begins with a comprehensive introduction to membrane transporters and their function, structure, and regulation mechanisms. It then moves into the impact of diseases on transporters and how this may affect pharmacokinetics. The book also presents the latest advancements in transporter-mediated drug delivery, examines the roles of both efflux and influx transporters in drug pharmacokinetics, and covers different strategies for utilizing membrane transporters for drug delivery and targeting specific tissues and cell types.It concludes with a discussion on the regulatory and industrial aspects of transporter-related projects, explores the potential of artificial intelligence in transporter and drug delivery research, and offers a glimpse into future challenges and perspectives in this field.
  • Cellular Therapies for Cancer Treatment

    Advancements in Drug Delivery Strategies
    • 1st Edition
    • Arun Kumar Singh + 3 more
    • English
    Cellular Therapies for Cancer Treatment: Advancements in Drug Delivery Strategies explores the innovative use of cellular therapy to combat cancer, placing an emphasis on state-of-the-art delivery approaches. By covering a variety of cellular therapies for cancer, such as stem cells, immune cells, and others, this book provides a comprehensive introduction to the field. It describes ways to deliver drugs that target cancer cells more efficiently, decrease off-target effects, and enhance therapy outcomes. Sections provide a brief overview of cancer cell biology, describe the need for advance drug delivery systems, and address challenges and future directions.The book also goes into the ideas behind cellular therapies and how they may overcome drug resistance and make existing cancer treatments more effective. By elaborating on the value of diversity and inclusion in cancer research and treatment, the book also emphasizes the importance of all patients having equal access to innovative therapies. All things considered, this book is a great tool for researchers, doctors, and students in the cancer treatment sector.
  • Biopolymer Based Nano Drug Delivery for Cancer Wound Healing

    • 1st Edition
    • Vipan Kumar + 5 more
    • English
    Biopolymer Based Nano Drug Delivery for Cancer Wound Healing explores groundbreaking advancements in nanomedicine's role in treating cancer and promoting wound healing. The book delves into the pathophysiology of cancerous wounds, introduces biopolymer-based nanomedicine, and examines drug delivery systems using biopolymer-based nanoparticles. It concludes with future prospects of biopolymers in antitumor drug delivery systems. This resource is invaluable for researchers, advanced students, and R&D personnel across various fields, including cancer research, polymer science, biomaterials, biomedicine, pharmaceutics, biotechnology, and chemistry. Each chapter bridges theoretical concepts with practical applications, providing examples to illustrate key points.The book covers the pathophysiology of cancer and wounds, biopolymer-based nanomedicine for cancerous wounds, and drug delivery systems for healing. This is an essential reference for scientists and students focusing on pharmacy, drug delivery, and biomedicine.
  • Nanoengineered Therapeutics for Lung Cancer

    Advanced Drug Delivery Strategies
    • 1st Edition
    • Arun Kumar Singh + 4 more
    • English
    Nanoengineered Therapeutics for Lung Cancer: Advanced Drug Delivery Strategies explores contemporary methods for diagnosing and treating lung cancer using cutting-edge nanotechnology. The book provides a foundational understanding of lung cancer biology, detailing innovative nanodrug delivery strategies and their practical applications in treatment. The content is strategically structured, covering the design, synthesis, and application of nanodrug delivery systems. Chapters delve into specific technologies such as gold nanoparticles, exosome-mediated therapies, and siRNA-based gene silencing. The book also addresses challenges like drug resistance and toxicity, offering insights into future research directions and advancements in the field. This book benefits graduate students, researchers, and healthcare professionals by seamlessly integrating theoretical concepts with practical applications. It serves as an essential educational resource, equipping readers with the knowledge and skills needed to tackle complex challenges in lung cancer treatment using nanomedicine. This comprehensive guide ensures that readers stay at the forefront of the rapidly evolving landscape of cancer therapeutics.
  • CDK4/6 inhibitors in Breast Cancer Therapy

    • 1st Edition
    • Pankaj Kumar Singh + 3 more
    • English
    CDK4/6 inhibitors in Breast Cancer Therapy examines the pivotal role of CDK4/6 inhibition in treating hormone receptor-positive (HR+)/HER2-negative advanced breast cancer. The book highlights FDA-approved applications of these inhibitors alongside endocrine therapy and explores ongoing research into their potential as neoadjuvant treatments. It provides insights into the drug discovery and development of CDK4/6 inhibitors, covering their molecular mechanisms, pharmacology, and clinical applications. Chapters address their use in mono and adjuvant therapies, as well as challenges in targeting, while also discussing market potential and post-marketing safety issues.This book is a valuable resource for researchers and academics, enhancing understanding of CDK4/6 inhibitors' chemistry and therapeutic implications. By presenting detailed information on clinical trials and market formulations, it equips the audience with essential knowledge to navigate the complexities of targeted breast cancer therapies and contributes to advancing research in this critical area.
  • Advanced Cancer Therapeutics

    Strategies and Technologies for Targeted Drug Delivery
    • 1st Edition
    • Manish Kumar + 2 more
    • English
    Advanced Cancer Therapeutics: Strategies and Technologies for Targeted Drug Delivery explores the heterogeneity of tumors and microenvironmental factors that influence cancer treatment and contribute to drug resistance. The book discusses critical elements such as tumor stroma, vasculature, pH, hypoxia, and enzymatic activity that impact therapeutic efficacy. Sections cover advanced drug formulations, including supramolecular systems, metal-organic frameworks, and nanomedicine, focusing on their roles in selective drug delivery for early detection, diagnosis, and treatment of various cancers. In addition, it reviews the current status and future perspectives of these formulations, highlighting their potential to enhance therapeutic outcomes while minimizing side effects.Readers will also find discussions on the limitations of nanocarriers, along with regulatory and ethical considerations related to anticancer formulations. This resource is invaluable for researchers, clinicians, and students, offering insights into the latest advancements in drug delivery systems.
  • Targeting Intercellular Communication with Nanomedicine and Advanced Therapeutics

    • 1st Edition
    • Lara Scheherazade Milane + 1 more
    • English
    Targeting Intercellular Communication with Nanomedicine and Advanced Therapeutics delves into the complex world of intercellular communication biology and its implications on therapeutics. This book covers all areas of intercellular communication and therapeutics in development for different forms of communication, including their role in diseases such as cancer, neurological disorders, metabolic diseases, and inflammatory/immune diseases. Sections provide an introduction, biological targets, challenges, and approaches to overcoming biological barriers and the significance of contact points and mechanisms of internalization. Specifics of tunneling nanotubes, extracellular vesicles, and the immune and non-immune interface in various diseases are covered. Furthermore, the book explores the crosstalk of different forms of intercellular communication and the implications of mitochondrial exchange in the four primary pathological areas. This is an essential resource for researchers, students, and professionals in the field of drug development and delivery. By connecting the dots between extracellular vesicles, tunneling nanotubes, and cell-cell junctions, this book serves as a foundation for further advancements in the science of intercellular communication and it's applications to new drug discovery and delivery.
  • The Future of Pharma Across All Sectors in the Artificial Intelligence Era

    • 1st Edition
    • Miltiadis Lytras + 5 more
    • English
    The Future of Pharma Across All Sectors in the Artificial Intelligence Era offers a thorough examination of the pharmaceutical industry's current landscape, highlighting the myriad challenges, opportunities, and trends that are poised to shape its future. Edited by experts, this book delves into transformative technological advancements, including artificial intelligence, machine learning, big data analytics, and blockchain. These technologies are redefining pharmaceutical research, development, and commercialization, making precision medicine and personalized therapies a reality, while integrating genomic medicine into the pharmaceutical value chain.Additionally, the book addresses educational implications for academic curricula, emphasizing the need for digital transformation in healthcare delivery models. It scrutinizes regulatory trends and compliance, offering insights into navigating complex landscapes to ensure product quality and safety. The book emphasizes the pharmaceutical industry's role in tackling infectious diseases and health disparities, promoting health equity through innovative drug development and access initiatives. Future trends and predictions are speculated upon, considering demographic shifts and evolving healthcare needs, while market dynamics and commercial strategies are analyzed to equip pharmaceutical companies with practical recommendations for navigating competitive landscapes.
  • Nonthermal Extraction Technologies of Polysaccharides

    Principles, Techniques, Characterization, and Applications
    • 1st Edition
    • Seyed Mohammad Taghi Gharibzahedi
    • English
    Nonthermal Extraction Technologies of Polysaccharides: Principles, Techniques, Characterization, and Applications explores cutting-edge nonthermal extraction technologies, including ultrasound, microwave, high-pressure, pulsed electric field, enzymatic extraction methods, and cold plasma technology and their effects on polysaccharide biofunctionalities, such as antioxidant and antimicrobial properties and potential applications. With an examination of the therapeutic benefits associated with these compounds, including anti-cancer, antioxidant, antimicrobial, anti-inflammatory, and anti-obesity properties, this book aspires to highlight advanced techniques to significantly enhance polysaccharide yield, bioactivity, and purity when compared to traditional approaches.The initial chapters introduce the fundamental structures, sources, and importance of polysaccharides, thus setting the stage for a deeper understanding of their functionality and chemical characterization. By offering both theoretical frameworks and practical guidance, this book equips professionals with the knowledge required to effectively incorporate polysaccharides into health-promoting products for advancing research and applications in the evolving landscape of functional foods and biomedical innovation.