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Elsevier

Topical Dermal Drug Delivery

Concepts and Advances

  • 1st Edition - October 1, 2026
  • Latest edition
  • Editors: Jitender Madan, Tathagata Dutta, Rupinder Kaur Sodhi, Ravi Shankar Pandey, Ramesh Chandra
  • Language: English

Topical Dermal Drug Delivery: Concepts and Advances compiles, in a single volume, the most recent advances in topical and dermal formulations for the treatment of skin disorders… Read more

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Description

Topical Dermal Drug Delivery: Concepts and Advances compiles, in a single volume, the most recent advances in topical and dermal formulations for the treatment of skin disorders.

The book covers three major concepts. The skin anatomy and physiology part includes chapters focused on relevant information for drug delivery. The second part of the book deals with several recent topical dermal drug delivery systems, including computational methods, permeation enhancers, bio precursors, hydrogels, emugels, exosomes and several nanotechnology enabled systems. The third and final part covers scaling up, toxicity, clinical trials, and regulatory considerations.

This is a complete reference for academic and corporate pharma researchers investigating targeted drug delivery to the skin. Medical & Health Sciences researchers would also benefit from understanding the delivery systems covered in this book.

Key features

  • Includes coverage of skin structure, physiology, pharmacology, and skin disorders
  • Covers updated methods and techniques for the customization of novel topical dermal drug delivery systems
  • Provides a comprehensive compilation of marketed and clinical trials of novel topical dermal drug delivery systems

Readership

Pharmaceutical scientists, organizations and industries working in the field of drug discovery, drug development and formulation, repurposing and pharmacological interpretations, Pharmaceutical and biomedical research and development sector: including pharmaceutical and biotechnology industry

Table of contents

1. Anatomy, Physiology and Immunology of Skin: What to know?

2. An Introduction to Skin diseases: Pathology and Therapeutics

3. Topical dermal drug delivery systems: Conceptualization and advancements

4. Dermatopharmacokinetic: Assessment tools for topically applied dosage forms

5. Artificial Intelligence, Machine learning, and Pharmacoinformatics: A headway to topical dermal drug delivery

6. Permeation enhancers for topical dermal drug delivery

7. Film forming topical dermal drug delivery systems: Basics and advances

8. Prodrug and bioprecursors for topical dermal dug delivery

9. Hydrogels and self-healing hydrogels for topical dermal drug delivery: Journey from bench to market

10. Emulgel: An integrated novel drug delivery system

11. Liposomes as topical dermal drug delivery systems: Lab to bedside

12. Niosomes for topical dermal drug delivery: Preclinical and clinical milestones

13. Transfersomes for topical dermal drug delivery: A matchless carrier

14. Polymersomes for topical dermal drug delivery: Basic views and advancements.

15. Phytosomes for topical dermal drug delivery: Concept and advances

16. Exosomes for topical dermal drug delivery: Recent progress and future Perspectives

17. Polymeric micelles for topical dermal drug delivery: Design, synthesis and applications

18. Lipid nanoparticles for topical dermal drug delivery: Preclinical and clinical advances

19. Polymeric nanoparticles for topical dermal drug delivery: Design and applications

20. Polymeric microparticles for topical dermal drug delivery

21. Dendrimers for topical dermal drug delivery: Recent progress

22. Non-invasive approaches for skin delivery

23. RNA therapeutics for topical dermal drug delivery: From bench to benchside

24. Topical immunization for skin disorders

25. Toxicological considerations of novel topical dermal drug delivery systems

26. Scale up and clinical translation of topical dermal drug delivery products

27. Regulatory framework for development of novel topical dermal drug delivery systems

Product details

  • Edition: 1
  • Latest edition
  • Published: October 1, 2026
  • Language: English

About the editors

JM

Jitender Madan

Dr. Jitender Madan is Associate Professor and Head of the Department of Pharmaceutics at NIPER Hyderabad, a leading researcher and educator in pharmaceutical sciences. His research centers on self-assembled supramolecular systems—liposomes, niosomes, cyclodextrins, nano- and microparticles, and solid-lipid nanoparticles—and leverages FDA-approved biomaterials with lipids and polymers to develop innovative dosage forms that improve bioavailability, stability, safety, and patient compliance. He has mentored numerous doctoral and postgraduate scholars and led industry collaborations and government-funded projects. Notable products include cycloencapsulated andrographolide for immune support and a veterinary spray for bovine mastitis. He has authored a robust body of peer-reviewed papers and book chapters, holds several patents, and has edited nanotechnology-focused volumes. A recognized educator and researcher, he actively contributes as a peer reviewer and advances pharmaceutical science and education through programs like SRIP.

Whilst a wide range of applications are being taken up, the special emphasis is given to augment the aqueous solubility and bioavailability of lipophilic drugs.
Affiliations and expertise
Associate Professor, National Institute of Pharmaceutical Education and Research, Hyderabad, Telangana, India

TD

Tathagata Dutta

Dr. Tathagata Dutta has earned his M.Pharm and PhD in Pharmaceutical Sciences from Dr. Hari Singh Gour University, Sagar and completed his postdoctoral studies from School of Pharmacy & Diamantina Institute for cancer, Immunology and Metabolic Medicine, University of Queensland, Brisbane, Australia and was engaged in development of RNAi therapeutics for effective management of cancer. He has served as Chief Scientific Officer (CSO), Vice President (R&D), Executive Director, Managing Director & CEO of several reputed Multinational Pharmaceutical Companies for more than two decades. He is the editorial board member of several international journals on drug discovery & delivery research. His research interests include novel drug delivery systems, dendrimers, liposomes, polymer bioconjugates, tissue targeted drug delivery systems, nano drug delivery systems, gene therapy, genetic immunization, depot injections, gene delivery, and development of RNAi therapeutics. Presently, he is the Chief Technology Officer (CTO) of JODAS EXPOIM Pvt Ltd.
Affiliations and expertise
Chief Technology Officer, Jodas Expoim Private Limited, Hyderabad, Telangana, India

RS

Rupinder Kaur Sodhi

Dr. Sodhi has a doctorate in pharmacology with more than 14 years of experience in guiding the postgraduate students for scientific projects in an academic setting. While teaching, he strongly emphasizes the use of bioinformatics tools for literature survey, formulation of hypothesis, and guide students to publish their research work in peer reviewed journals. I am also delivering lessons to postgraduate students in drug evaluation techniques and animal models used in experimental pharmacology. He is a Coordinator/ Member Secretary for Institutional animal’s ethical committee (IAEC) for the conduct of the meetings for the approval of experimental animals. He is actively engaged in maintaining the animal house facilities per the norms.
Affiliations and expertise
Professor, Department of Pharmacology, Chandigarh College of Pharmacy, Mohali, Punjab, India

RP

Ravi Shankar Pandey

Dr. Ravi Shankar Pandey is presently a Professor in the Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur C.G. India. He has authored two book chapters in international publishers. He has published more than 44 research papers in reputed peer-reviewed journals. He has presented many papers and participated as a resource person in International and National conferences. He has guided three PhD students, and four research scholars are doing research under his guidance. He is a reviewer of various international journals. He has 21 years of teaching experience in undergraduate and postgraduate pharmacy courses with more than 14 years of research experience. He has guided several undergraduate and postgraduate students in their project work. Moreover, as a guest PhD student, he worked at the University of Copenhagen, Denmark. He is a life member of professional bodies such as the Indian Science Congress and the Association of Pharmaceutical Teachers of India. He is a registered pharmacist at the State Pharmacy Council of Chhattisgarh, India. He has received grants from the University Grants Commission New Delhi and the Indian Council of Medical Research New Delhi for research in vaccine and protein drug delivery.
Affiliations and expertise
Professor, Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur C.G. India

RC

Ramesh Chandra

Prof. Ramesh Chandra is a distinguished scientist and Fellow of the Royal Society of Chemistry, London, recognized for his contributions to Biomedical Sciences. He currently serves as Vice-Chancellor of Maharaja Surajmal Brij University, Rajasthan, and is the Founder Director of the Dr. B. R. Ambedkar Center for Biomedical Research at the University of Delhi. Prof. Chandra has held prominent positions including Vice-Chancellor of Bundelkhand University and Head of the Department of Chemistry at the University of Delhi. He has also served as an official resource person to the Minister and Department of Science and Technology in Lesotho, South Africa. His research career spans prestigious institutions such as Cornell University, Rockefeller University, Harvard Medical School, and MIT.

He started his research career at the University of Delhi, then at The New York Hospital-Cornell University Medical College, and The Rockefeller University, New York; State University of New York at Stony brook, New York; Harvard University Medical School-Massachusetts General Hospital (MGH) jointly at MIT, Cambridge, MA, USA.

Prof. Chandra has been Vice-Chancellor, Bundelkhand University, Jhansi (1999-2005) as well as President of the Indian Chemical Society, Member, Planning Commission, Government of U.P. India; Secretary - Zaheer Science Foundation, New Delhi and Non-Official Director, Rashtriya Ispat Nigam Ltd, Government of India. He was also Head of the Department of Chemistry, University of Delhi.

He is recipient of several international recognitions: J. William Fulbright Scholarship, The Rockefeller Foundation USA-Biotechnology Career Award, Award of the Highest Honor of Soka University, Tokyo, Japan; Millennium Plaques of Honor (Life Time Achievement Award for contribution in Science & Technology) by the Indian Science Congress Association (ISCA), Lifetime Achievement Award of the Indian Chemical Society (ICS); UGC Research Scientist Award; UGC Career Award; Rajib Goyal Award for Young Scientists and others.

Prof. Chandra shows deep commitment to the cause of higher education & research and possesses in ample measure quality of dynamic leadership, vision required for building academic institutions and excelled in his academic pursuits. To illustrate, he has to his credit several international patents, 9 Books; 28 Book Chapters; and more than 387 original Scientific Research Papers in International journals of repute. He has mentored more than 100 Ph.D students.

Affiliations and expertise
Vice-Chancellor, Maharaja Surajmal Brij University, Bharatpur, Rajasthan, India