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Advances in Immunology

  • 1st Edition, Volume 156 - November 19, 2022
  • Latest edition
  • Editors: Frederick W. Alt, Kenneth Murphy
  • Language: English

Advances in Immunology, Volume 156, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunolog… Read more

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Description

Advances in Immunology, Volume 156, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology, with this volume covering self-referential immune recognition through C-type lectin receptors, genetic susceptibility to autoimmunity, activation and regulation of the cGAS-STING pathway and the implications of IL-15 trans-presentation on the immune response.

Key features

  • Presents current developments and comprehensive reviews in immunology
  • Provides the latest in a longstanding and respected serial on the subject matter
  • Focuses on recent advances in the advancing area of the mechanisms involved in the evolution of regulatory T-cells in infection and Factor H and Properdin and their regulation

Readership

Immunologists and infectious disease specialists, cell biologists and hematologists

Table of contents

1. Self-referential immune recognition through C-type lectin receptors

Carla Guenther, Masamichi Nagae and Sho Yamasaki

2. Genetic susceptibility to autoimmunity: Current status and challenges

Miaozhen Huang and Huji Xu

3. Recent advances in the activation and regulation of the cGAS-STING pathway

Run Fang, Qifei Jiang, Xiaoyu Yu, Zhen Zhao and Zhengfan Jiang

4. The implications of IL-15 trans-presentation on the immune response

Thomas A. Waldmann, Robert Waldmann, Jian-Xin Lin and Warren J. Leonard

Product details

  • Edition: 1
  • Latest edition
  • Volume: 156
  • Published: November 19, 2022
  • Language: English

About the editors

FA

Frederick W. Alt

Frederick W. Alt is a Howard Hughes Medical Institute (HHMI) Investigator and Director of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital (BCH). He is the Charles A. Janeway Professor of Pediatrics and Professor of Genetics at Harvard Medical School. He works on elucidating mechanisms that generate antigen receptor diversity and, more generally, on mechanisms that generate and suppress genomic instability in mammalian cells, with a focus on the immune and nervous systems. Recently, his group has developed senstive genome-wide approaches to identify mechanisms of DNA breaks and rearrangements in normal and cancer cells. He has been elected to the U.S. National Academy of Sciences, the U.S. National Academy of Medicine, and the European Molecular Biology Organization. His awards include the Albert Szent-Gyorgyi Prize for Progress in Cancer Research, the Novartis Prize for Basic Immunology, the Lewis S. Rosensteil Prize for Distinugished work in Biomedical Sciences, the Paul Berg and Arthur Kornberg Lifetime Achievement Award in Biomedical Sciences, and the William Silan Lifetime Achievement Award in Mentoring from Harvard Medical School.
Affiliations and expertise
Investigator and Director, Program in Cellular and Molecular Medicine, Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA

KM

Kenneth Murphy

Kenneth M. Murphy works in Washington University School of Medecine, USA.
Affiliations and expertise
Washington University School of Medecine, USA

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