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Elsevier

Aminoff's Diagnosis of Neuromuscular Disorders

  • 4th Edition - January 5, 2024
  • Latest edition
  • Authors: Michael J. Aminoff, Jeffrey W. Ralph, Francis Walker
  • Language: English

**Selected for 2026 Doody's Core Titles as an Essential Purchase in Neurology**Succinct yet comprehensive, Aminoff's Diagnosis of Neuromuscular Disorders, 4th Edition, provides… Read more

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**Selected for 2026 Doody's Core Titles as an Essential Purchase in Neurology**

Succinct yet comprehensive, Aminoff's Diagnosis of Neuromuscular Disorders, 4th Edition, provides expert information and guidance on the clinical, electrodiagnostic, and imaging aspects of neuromuscular disorders. Fully updated, it reflects important advances in the field, including an improved understanding of the molecular and genetic basis of neuromuscular disease, an expanded use of next-generation genetic testing, refinements in electrodiagnosis, and the use of ultrasound imaging techniques to evaluate the peripheral nervous system. In-depth discussions of disease states, as well as the evidence supporting the use of electrodiagnostic and imaging techniques, moves this reference from simply answering the question “How?” to also answering “Why?”

Key features

  • Describes the range of clinical manifestations of individual neuromuscular diseases; the power and limitations of electrodiagnostic techniques as they relate to neuromuscular disorders; the place of genetic studies in the diagnosis and prognostication of these diseases; and the scope and utility of newer imaging procedures in detecting and localizing the underlying pathologic process
  • Reviews neuromuscular physiology and the pathology of major diseases
  • Provides a readable, well-illustrated synthesis of clinical and investigative techniques in diagnosing neuromuscular diseases, with concise guidance on how to conduct clinical, electrodiagnostic, and ultrasound evaluations and the findings in various disease states
  • Covers a wide variety of electrodiagnostic and ultrasound procedures, including techniques for evaluating different individual nerves
  • Features video clips of waveforms and of ultrasound images to illustrate key concepts
  • An ideal resource for neuromuscular specialists, clinical neurologists, physiatrists, rehabilitation specialists, clinical neurophysiologists, and electromyographers, as well as trainees and those preparing for board certification in neurology, PM&R, neuromuscular medicine, clinical neurophysiology, and electrodiagnostic medicine
  • An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud

Readership

clinical neurologists and physiatrists, neuromuscular clinicians, and clinical neurophysiologists and electromyographers. It will also be an important reference source for trainees and those preparing for board certification in neurology, physiatry (physical medicine and rehabilitation), neuromuscular medicine, clinical neurophysiology, and electrodiagnostic medicine

Table of contents

PART I Introduction

1. Diagnosis of Neuromuscular Disorders

2. Biopsies and Neuromuscular Disease

3. Neuromuscular Imaging, 38

4. Genetic Evaluation of Neuromuscular Disorders

PART II Basic Aspects

5. Aspects of Nerve and Muscle Physiology

6. Properties and Functional Organization of Motor Units

7. Electrodiagnostic Apparatus

8. General Aspects of Needle Electromyography

9. Clinical Aspects of Needle Electromyography

10. Nerve Conduction Studies: Basic Principles and Pathologic Correlations

11. Quantitative and Related Techniques of Electromyography and Electroneurography

12. Other Neurophysiologic Techniques for the Evaluation of Neuromuscular Disorders

13. Evaluation of the Autonomic Nervous System

PART III Generalized Neuromuscular Disorders

14. Myopathic Disorders and Myalgia

15. Muscle Channelopathies

16. Motor Neuron Disorders

17. Muscle Fiber and Motor Unit Hyperactivity States

18. Polyneuropathy and Mononeuropathy Multiplex

19. Root and Plexus Lesions

20. Neuromuscular Transmission and Its Disorders

PART IV Focal Neuropathies

21. Traumatic Neuropathy and Surgical Interventions Focal Neuropathies in the Upper Limbs

22. Median Neuropathies

23. Ulnar Neuropathies

24. Radial Neuropathies

25. Disturbances of Other Nerves in the Upper Extremities Focal Neuropathies in the Lower Limbs

26. Fibular (Peroneal) Neuropathies

27. Tibial and Sural Neuropathies

28. Sciatic Neuropathies

29. Disturbances of Other Nerves in the Lower Extremities Cranial Nerves

30. Facial Neuropathies

31. Disturbances of Other Cranial Nerves and the Phrenic Nerve

PART V Central Nervous System

32. Electrophysiologic Evaluation of Selected Aspects of the Central Nervous System

Appendix

1: Glossary of Terms in Neuromuscular and Electrodiagnostic Medicine and Ultrasound
2: Nerve Reference Values for Ultrasonography
3: Videos

Review quotes

"This book is a clinical guide to approaching neuromuscular disorders through pathophysiology, diagnosis, and management. The book is mostly in text format; however, it has many pictures, tables, and graphs to easily find highlights. The accompanying website has the complete eBook as well as videos that complement examples of pathology. The previous edition was published in 1998." - ©Doody’s Review Service, 2024, Patricia J Graese, MD (Thomas Jefferson University), Doody’s Score: 100 - 5 Stars!

Product details

  • Edition: 4
  • Latest edition
  • Published: January 5, 2024
  • Language: English

About the authors

MA

Michael J. Aminoff

Dr. Michael J. Aminoff, Distinguished Professor Emeritus in neurology at the University of California San Francisco, is an internationally recognized neurologist, clinical investigator, and author. His published contributions led to the award of a Doctor of Science degree by the University of London in 2000. He is one of the two editors-in-chief of the four-volume Encyclopedia of the Neurological Sciences (2003; 2014) as well as one of the series editors of the multivolume Handbook of Clinical Neurology. He was editor-in-chief of the journal Muscle & Nerve from 1998 to 2007 and has served on numerous other editorial boards. He was a director of the American Board of Psychiatry and Neurology for eight years and served as board chair in 2011. In 2006, he received the Lifetime Achievement Award from the American Association of Neuromuscular & Electrodiagnostic Medicine and, in 2007, the A.B. Baker Award for Lifetime Achievement in Neurological Education from the American Academy of Neurology. In 2019 he received the Robert S. Schwab Award for outstanding contributions to research in peripheral clinical neurophysiology from the American Clinical Neurophysiology Society.
Affiliations and expertise
Distinguished Professor Emeritus in Neurology; University of California San Francisco, USA

JR

Jeffrey W. Ralph

Dr. Jeffrey W. Ralph directs the neuromuscular medicine fellowship program at the University of California San Francisco (UCSF). He completed a neurology residency as well as fellowship training in neuromuscular medicine and clinical neurophysiology at UCSF. Dr. Ralph is an expert in the electrodiagnosis of neuromuscular diseases and in the clinical management of these diseases, especially peripheral neuropathies, and since 2004 has directed the Neuropathy Center at UCSF Medical Center. His research has addressed treatments for neuropathy caused by HIV/AIDS and muscle channelopathies.

Affiliations and expertise
Clinical Professor; Director, Neuromuscular Medicine Fellowship Program; University of California San Francisco, USA

FW

Francis Walker

Dr. Francis O. Walker joined the faculty of Wake Forest University School of Medicine in 1984 and is currently Emeritus Professor of Neurology. He has published widely on clinical neuropharmacology, neurophysiology, and neuromuscular imaging and has helped in the training of numerous fellows and residents. He has served on several editorial boards, helped create self-assessment and certifying examinations in clinical neurophysiology, and held leadership positions in medical societies including a term as president of the American Association of Neuromuscular and Electrodiagnostic Medicine. Dr. Walker has been a pioneer in the development of ultrasound as a means of evaluating the neuromuscular system, and he is a co-editor of the book Neuromuscular Ultrasound.
Affiliations and expertise
Emeritus Professor of Neurology; Wake Forest University School of Medicine, USA