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An Introduction to Interdisciplinary Toxicology

From Molecules to Man

  • 1st Edition - February 18, 2020
  • Latest edition
  • Editors: Carey N. Pope, Jing Liu
  • Language: English

An Introduction to Interdisciplinary Toxicology: From Molecules to Man integrates the various aspects of toxicology, from “simple” molecular systems, to complex human communiti… Read more

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Description

An Introduction to Interdisciplinary Toxicology: From Molecules to Man integrates the various aspects of toxicology, from “simple” molecular systems, to complex human communities, with expertise from a spectrum of interacting disciplines. Chapters are written by specialists within a given subject, such as a chemical engineer, nutritional scientist, or a microbiologist, so subjects are clearly explained and discussed within the toxicology context. Many chapters are comparative across species so that students in ecotoxicology learn mammalian toxicology and vice versa. Specific citations, further reading, study questions, and other learning features are also included.

The book allows students to concurrently learn concepts in both biomedical and environmental toxicology fields, thus better equipping them for the many career opportunities toxicology provides. This book will also be useful to those wishing to reference how disciplines interact within the broad field of toxicology.

Key features

  • Covers major topics and newer areas in toxicology, including nanotoxicology, Tox21, epigenetic toxicology, and organ-specific toxicity
  • Includes a variety of perspectives to give a complete understanding of toxicology
  • Written by specialists within each subject area, e.g., a chemical engineer, to ensure concepts are clearly explained

Readership

Graduate students and advanced undergraduate students in toxicology programs. Students and researchers in medicine, environmental sciences, neuroscience, food sciences, computing, and fundamental life sciences needing information about toxicology information in their discipline

Table of contents

I. General Concepts

1. Principles

2. Sources of exposures: Point vs Nonpoint Source Contamination

3. How chemicals distribute in the physical environment

4. How chemicals distribute in cells and simple organisms

5. How chemicals distribute in complex organisms

II. Responses to chemical toxicants

6. Cellular responses to toxicants

7. Genotoxicity and epigenetics

8. Carcinogenesis

9. Disruption of cell signaling

10. Altered development and reproduction

11. Microbiome alterations and modulation of toxicity

12. Nanotoxicology

III. Organ System Effects

13. Dermal system

14. Gastrointestinal system

15. Excretory system

16. Respiratory System

17. Cardiovascular system

18. Musculoskeletal system

19. Endocrine system

20. The immune system

21. Visual system

22. Nervous system

IV. Ecosystems and Ecotoxicology

23. Organism vs population

24. Bioconcentration

25. Biomarkers

V. Toxicology in the Home

26. Opiates and other therapeutics

27. Cleaning products

28. Petroleum products

VI. Toxicology in the Community

29. Historical case studies

30. Social factors in community contamination

VII. Forensic Toxicology

VIII. Regulatory Toxicology

31. Toxicity testing

32. Tox21

33. Principles of Risk Assessment

IX. Reference materials and websites

34. Information Resources in Toxicology, 4th edition.

35. National Toxicology Program

36. National Center for Toxicological Research

37. FDA

38. EPA

Product details

  • Edition: 1
  • Latest edition
  • Published: February 21, 2020
  • Language: English

About the editors

CP

Carey N. Pope

Dr. Pope is the author of over 95 peer-reviewed papers. He is the Director of the Interdisciplinary Toxicology Program at Oklahoma State University as well as a member of the Food Quality Protection Act (FQPA) Board, U.S. Environmental Protection Agency, Washington, D.C.. He sits on the Editorial Board of many journals including: • Toxicological Sciences • Journal of Toxicology and Environmental Health • International Journal of Toxicology • Toxicology • Toxicology and Applied Pharmacology • Journal of Environmental Science and Health Part C • NeuroToxicology • Archives of Toxicology
Affiliations and expertise
Professor and Sitlington Endowed Chair in Toxicology, Department of Physiological Sciences, College of Veterinary Medicine; Director, Interdisciplinary Toxicology Program, Oklahoma State University-Stillwater

JL

Jing Liu

Dr. Liu’s research interests include the neurochemical and neurobehavioral effects of xenobiotics. She is interested in exogenous and endogenous factors that modulate the neurotoxicological effects of pesticides and other neurotoxicants.
Affiliations and expertise
Senior Research Scientist, Charles River Laboratories, Reno, NV; Adjunct Associate Professor, Department of Physiological Sciences, College of Veterinary Medicine, Oklahoma State University-Stillwater

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