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Antidiabetic Drug Discovery from Natural Products

  • 1st Edition - June 12, 2025
  • Latest edition
  • Editors: Shailendra S. Gurav, Uchenna Estella Odoh, Nilambari S Gurav, Yogesh A. Kulkarni, Rupesh Chikhale
  • Language: English

Antidiabetic Drug Discovery from Natural Products provides up-to-date and in-depth information, practical understanding, and guidance in a comprehensive, systematic and easy-t… Read more

Description

Antidiabetic Drug Discovery from Natural Products provides up-to-date and in-depth information, practical understanding, and guidance in a comprehensive, systematic and easy-to-understand manner to scientists, researchers, and graduate students on important and emerging biochemical topics related to current antidiabetic drug discovery research. This book analyzes and studies natural active substances and their medicinal chemistry in preventing and treating diabetes and its complications. It covers a wide range of critical issues to assist chemists in the discovery and development of safer, more affordable treatments, from identifying promising leads from medicinal plants to the extraction and synthesis of bioactive compounds.

Following an introduction to bioactive chemical compounds from plants with antidiabetic effects, the book describes the discovery and extraction of antidiabetic drugs and antioxidants from natural sources. It also examines antidiabetic plants before delving deeper into the chemistry behind major medicinal substances and their derivatives like Mangiferin and Resveratrol, discussing both current and prospective uses.

Key features

  • Covers the history and current trends in antidiabetic natural product research
  • Focuses on each class of natural products and their therapeutic effects on diabetes
  • Analyzes the specific roles of different plant metabolites in the treatment of diabetes

Readership

Graduate students and researchers working with drug discovery, Medicinal Chemistry, toxicology and natural products

Table of contents

Section 1: Putative antidiabetic drugs

1. Natural products in antidiabetic drug discovery: Historical perspective

2. Natural products in antidiabetic drug discovery: advances and opportunities

Section 2: Plant bioactives and their antidiabetic potential

3. Antidiabetic flavonoids from plant source

4. Antidiabetic terpenoids from plant source

5. Antidiabetic potential of plant alkaloids

6. Antidiabetic carbohydrates from natural sources

7. Antidiabetic potential of glycosides

8. Antidiabetic potential of tannins

9. Biological macromolecules as antidiabetic agents

10. Antidiabetic drugs from fungi

11. Antidiabetic secondary metabolites from marine source

Section 3: Pharmacological mechanism

12. Screening of antidiabetic drugs: in-vitro approaches

13. Animal models for screening of antidiabetic drugs from natural sources

14. Molecular Mechanisms of secondary metabolites as antidiabetic agents

15. Network pharmacology approach for antidiabetic drugs from natural sources

Section 4: Natural antidiabetics: Nature to clinic and market

16. Recent advances in natural antidiabetics

17. Antidiabetic drugs: Marketed formulations and case studies

18. Antidiabetic drugs: Patent case studies

19. Natural antidiabetic herbs and drug interactions

Product details

  • Edition: 1
  • Latest edition
  • Published: June 12, 2025
  • Language: English

About the editors

SG

Shailendra S. Gurav

Dr Shailendra S. Gurav has a Doctorate in the Faculty of Medicine from RTM University Nagpur, India and is currently affiliated as a Professor at Goa College of Pharmacy, Goa, India. Dr Gurav is the recipient of the ‘Senior Research Fellowship’ of the ‘Indian Council of Medical Research’, New Delhi, India and was also awarded the ‘International Travel Fellowship’ by ICMR, CICS, and the Phytochemical Society of Europe and Asia. He serves as 'Advisor' for 'American Herbal Pharmacopeia', Associate Editor for the Journal of Ayurveda and Integrative Medicine (Elsevier), Guest Editor for Frontiers in Pharmacology, and Editorial Board member and Reviewer for several International journals. He has published more than 80 research papers in International and National peer-reviewed journals. Currently, 11 book chapters, 02 books, and 04 Indian patents are in his credit. His research interests are Ayurveda Biology, Natural Products Research, Computational Biology and Herbal Nanotechnology.

Affiliations and expertise
Professor, Goa College of Pharmacy, Goa, India

UO

Uchenna Estella Odoh

Prof. Mrs. Uchenna Estella Odoh holds B. Sc degree in Pure and Industrial Chemistry, Master’s Degree in Pharmaceutical and Medicinal Chemistry, Master’s Degree in Pharmacognosy and Environmental Medicines and Ph.D in Pharmaceutical and Medicinal Chemistry all from the University of Nigeria, Nsukka. She is a Professor in the Department of Pharmacognosy and Environmental

Affiliations and expertise
Professor, Department of Pharmacognosy and Environmental, University of Nigeria Nsukka, Nigeria

NG

Nilambari S Gurav

Dr. Nilambari S. Gurav has a Doctorate in Pharmaceutical Sciences from SGBA University Amaravati, India and currently affiliated as an Assistant Professor at PES’s Rajaram and Tarabai Bandekar College of Pharmacy,Ponda, Goa University, India. Dr. Gurav is the recipient of the ‘Junior Research Fellowship’ of University Grants Commission, New Delhi, India. She has published more than 50 research papers in International and National peer-reviewed journals. Currently, 07 book chapters, 02 books, and 04 Indian patents are in her credit. Her research interests are Ayurveda Biology, Natural Products Research, Computational Biology and Herbal Nanotechnology.

Affiliations and expertise
Assistant Professor, PES’s Rajaram and Tarabai Bandekar College of Pharmacy, Ponda, Goa University, India

YK

Yogesh A. Kulkarni

Dr. Yogesh A. Kulkarni works as an Associate Professor and Associate Dean at Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, SVKM’s NMIMS, Mumbai. He has 17 years of teaching and research experience. His research focuses on the pharmacology of natural products. He is studying the effects of various natural products on diabetes and its complications. He has published 105 papers in the journal of repute. Dr. Yogesh has authored 09 books, 26 book chapters and filed 02 patents. He has fetched over Rs.1.5 crore in research funding from various agencies. He is the recipient of the prestigious “DST-INSPIRE Faculty Award” given by Govt. of India.

Affiliations and expertise
Associate Professor and Associate Dean, Shobhaben Pratapbhai Patel School of Pharmacy and Technology Management, SVKM’s NMIMS, Mumbai, India

RC

Rupesh Chikhale

Dr Rupesh V. Chikhale earned his Ph.D. in Pharmaceutical Sciences from Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, Maharashtra (India) in 2015. He specializes in medicinal chemistry and computer-aided drug discovery. He works as a postdoc at the University of Manchester and the UCL School of Pharmacy, London, UK.
Affiliations and expertise
University of Manchester and UCL School of Pharmacy, London, UK

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