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Elsevier

Antimicrobial Peptides

Challenges and Future Perspectives

  • 1st Edition - November 23, 2022
  • Latest edition
  • Editors: K. Sreejith, K. Ajesh
  • Language: English

Antimicrobial Peptides: Challenges and Future Perspectives covers the latest developments about antimicrobial peptides in the scenario of drug resistance. The book is divided i… Read more

Description

Antimicrobial Peptides: Challenges and Future Perspectives covers the latest developments about antimicrobial peptides in the scenario of drug resistance. The book is divided into 16 chapters arranged in sequence and preceded by chapters on historical developments and their role as regulatory molecules in innate defense mechanism. Emphasis is given to purification techniques and characterization suitable for interdisciplinary research. Chapters provide an inventory of various antimicrobial peptides, from a diverse array of organisms such as bacteria, fungi, insects, amphibians, plants and mammals. A section on marine ecosystem broadens readers understanding on marine based antimicrobial peptides.

Additional sections provide an informative overview on peptides with antiviral properties and those targeting multi-drug resistant bacteria. Recent reports and mechanism on resistance against antimicrobial peptides are also provided, along with key insights into the challenges and future perspectives of peptide drug development.

Key features

  • Emphasizes antimicrobial peptides targeting various human viruses and multidrug resistant bacteria
  • Written by internationally recognized experts who provide readers with a wide and useful perspective
  • Provides in-depth resources for undertaking a research work in antimicrobial peptides with the inclusion of chapters on purification techniques and structural details
  • Addresses the possibility and availability of peptide antibiotics in the global drug market
  • Serves as a complete resource from the discovery to drug development of peptide antibiotics

Readership

students as well as teachers and researchers in microbiology, molecular biology, biochemistry, and other allied disciplines

Table of contents

1. Historical developments of antimicrobial peptide research

2. Biosynthesis of peptide antibiotics and innate immunity

3. Antimicrobial peptides: features and mode of action

4. Purification techniques and characterisation of antimicrobial peptides

5. Peptide antibiotics from bacteria

6. Antimicrobial peptides of fungal origin

7. Insect peptides with antimicrobial effect

8. Amphibian host defence peptides

9. Plant derived antimicrobial peptides

10. Mammalian antimicrobial peptides

11. Antimicrobial peptides from marine environment

12. Peptides with antiviral activities

13. Peptide antibiotics against MDR bacteria

14. Antimicrobial peptide resistance

15. Recent advances and challenges in peptide drug development

16. Future perspective of peptide antibiotic market

Product details

  • Edition: 1
  • Latest edition
  • Published: November 23, 2022
  • Language: English

About the editors

KS

K. Sreejith

He is also the Research Director of Kannur University since 2018. Dr. Sreejith has received MPhil in Biophysics and PhD in Biochemistry from Mahatma Gandhi University, Kerala, India. He has more than 19 years of teaching and research experience. His area of research is antimicrobial peptides and proteins, anti inflammatory compounds and cancer biology. Since 2008, his team has contributed extensively in the aforementioned area with publications appearing in the Journal of Applied Microbiology, Applied Biochemistry and Biotechnology, Peptides, Mycopathologia. He has presented papers in the II International conference on antimicrobial research, Lisbon, Portugal-2012 and European Congress of Clinical Microbiology & Infectious Diseases (ECCMID), Amsterdam (Netherlands) in 2016. He is a life member of Indian Peptide Society (IPS). Since 2003 he has been serving Kannur University in its Board of studies in Microbiology as a member and from 2010 onwards he is the Chairman. He is having collaboration with researchers, Dr Sudarslal, Professor, School of Biotechnology, Amrita Vishwa Vidyapeetham, Kerala, India, and Dr C Arunan, School of Chemical Sciences, Mahatma Gandhi University, Kerala, India
Affiliations and expertise
Professor, Department of Biotechnology and Microbiology, Kannur University, Kerala, India

KA

K. Ajesh

He has completed his masters in Microbiology from Kuvempu University, Karnataka, India and received PhD in Microbiology from Kannur University, Kerala India. His area of research is peptide antibiotics, biofilms, drug resistance and Phage therapy. He has more than five years of teaching and research experience. His contribution in antimicrobial peptides and drug resistance appeared in various journals including-peptides, Journal of Applied microbiology, Applied Biochemistry & Biotechnology, Mycopathologia. He has been Board of studies member in Microbiology (2014-18) and Chairman, Board of Examiners in Biotechnology and Microbiology (2012-15), Kannur University. He is a reviewer of Journal of Bacteriology and Mycology. He is a member of Indian Peptide Society (IPS), Indian Initiative for Management of Antibiotic Resistance (IIMAR) and International Society for Viruses of Microorganisms (ISVM).
Affiliations and expertise
Faculty, Department of Biotechnology and Microbiology, Kannur University, India

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