Applications of Fluoropolymers in Medical Devices
- 1st Edition - November 1, 2026
- Latest edition
- Author: Sina Ebnesajjad
- Language: English
Fluorinated polymers have exceptional properties such as chemical resistance, neutral surfaces, modest mechanical properties, low coefficient of friction, resistance to flex… Read more
Description
Description
Fluorinated polymers have exceptional properties such as chemical resistance, neutral surfaces, modest mechanical properties, low coefficient of friction, resistance to flex fatigue and excellent performance at extreme high and low temperatures. Owing to these properties, fluoropolymers have been widely used in biomedical applications. Applications of Fluoropolymers in Medical Devices provides practical and comprehensive information on the structure, characteristics, properties, and processing methods of fluoropolymers commonly used for biomedical applications, along with a thorough description of several different medical devices containing fluoropolymers. The first part of this book describes material biocompatibility and fluoropolymers used in medical devices. Fluoropolymer types, properties and processing of parts, shapes, coatings and PTFE, such as microporous membrane and ePTFE, are discussed. The second part describes important devices containing fluoropolymers, and include a detailed overview of the design, fabrication methods, applications, and competitive materials of these devices. This book is the most authoritative reference to the subject available, and a valuable reference to scientists and engineers working in the medical device and technology areas.
Key features
Key features
- Discusses the fundamentals of fluoropolymers and their applications in medical devices, making it ideal for readers in industrial and research roles
- Describes important devices containing fluoropolymers, from sutures and catheters to tissue meshes and cardiovascular devices
- Provides insights into the safety of fluoropolymers
- Includes classification and regulation of medical devices dictated by the US Food and Drug Administration
Readership
Readership
Scientists and engineers working in the medical device and technology areas. Device researchers and designers, fluoropolymer manufacturers, and also research scientists at academic medical centers would benefit from this bookRegulatory agencies, standards organizations, and industry associations.
Table of contents
Table of contents
1. Introduction
1.1 Definition of Medical Devices
1.2 Applications of Medical Devices
1.3 Classification of Medical Devices
1.3.1 Diagnostic
1.3.2 Therapeutic
1.3.3 Implants
1.4 Medical Device Materials
1.5 Applications of Polymers in Medical Devices
2. Biocompatibility and Regulatory Compliance
2.1 Material Biocompatibility
2.2 Assessment of Compatibility
2.2.1 Testing Strategies
2.3 Biocompatibility Test Methods
2.4 Biocompatibility of Fluoropolymers
3. Fundamental Characteristics and Properties of Fluorinated Polymers
3.1 Uniqueness of Fluorine
3.2 Role C-F Bond in Fluoropolymers
3.3 Fluoropolymer Types: Homopolymers and Copolymers
4. Modification of Fluoropolymer Surfaces
4.1 Perfluorinated and Partially Fluorinated Surfaces.
4.2 Methods for Surface modification of Fluoropolymers
4.3 Surface Tuning and Grafting of PTFE by Plasma Treatment
5. Assessment of Fluoropolymers for use in Medical Devices
5.1 Introduction
5.2 Polymer characterization
5.3 Sterilization
5.4 Chemical resistance
5.5 Identification of extractable and leachable material
5.6 Biocompatibility
5.7 Shelf life and stability
6. Fluoropolymer Parts for Medical Devices
6.1 Microporous Membranes
6.2 Films and Sheets
6.3 Tubes (e.g. heat shrink)
6.4 Rods
6.5 Densified Films
7. Sterilization and Disinfection of Fluoropolymer Parts
7.1 Introduction
7.2 Definitions of Sterilization and Disinfection
7.3 Commercial Sterilization Methods
7.4 Advantages/disadvantages of Sterilization Methods
8. Introducers
8.1 Introduction to Access (access, needles, wire, catheter)
8.2 Introducer types
8.3 Micro-introducers
8.4 Peel-away introducer
8.5 Tracheal tube introducers
9. Sutures (Sina Ebnesajjad)
9.1 Introduction and Types (PTFE, PTFE Coated)
9.2 Mono and Multi Filament
9.3 Surgical
9.4 Dental
10. Lead Assemblies (Patents)
10.1 Introduction
10.2 Types
10.3 Cardiac Devices
11. Catheters (Ali Ashter)
11.1 Introduction and Types
11.2 Multilumen Catheters
11.3 Guiding Catheters (active or passive manipulation)
11.4 External Catheters
11.5 MicroCatheters
11.6 Catheter Balloons
12. Cardiovascular Devices
12.1 Vascular Implants
12.2 Covered Stents
12.3 Prosthetic Heart Valves
12.4 Vena Cava Filters
13. ePTFE Tissue Meshes
14. Arteriovenous ePTFE Grafts for Dialysis
14.1 Introduction and Types
14.1.1 Access
14.2 Dialysis
15. Ligament Reconstruction and Replacement
16. Other Devices
16.1 Coated wire
16.2 Closure Device
16.3 Microfiltration Media
16.4 PTFE Coated Electrodes
16.5 Electrosurgical blades
16.6 Forceps
16.7 Surgical (Suture) Needles
17.7.1 Tapered Needles
17.7.2 Cutting Suturing Needles
16.8 Hypodermic Needles
16.9 Mini-Vacutron
17. Radiopacity
17.1 Introduction
17.2 Fluoroscopy and X-ray Imaging
17.3 Additives to impart Radiopacity
17.4 Applications of Radiopaque Devices
1.1 Definition of Medical Devices
1.2 Applications of Medical Devices
1.3 Classification of Medical Devices
1.3.1 Diagnostic
1.3.2 Therapeutic
1.3.3 Implants
1.4 Medical Device Materials
1.5 Applications of Polymers in Medical Devices
2. Biocompatibility and Regulatory Compliance
2.1 Material Biocompatibility
2.2 Assessment of Compatibility
2.2.1 Testing Strategies
2.3 Biocompatibility Test Methods
2.4 Biocompatibility of Fluoropolymers
3. Fundamental Characteristics and Properties of Fluorinated Polymers
3.1 Uniqueness of Fluorine
3.2 Role C-F Bond in Fluoropolymers
3.3 Fluoropolymer Types: Homopolymers and Copolymers
4. Modification of Fluoropolymer Surfaces
4.1 Perfluorinated and Partially Fluorinated Surfaces.
4.2 Methods for Surface modification of Fluoropolymers
4.3 Surface Tuning and Grafting of PTFE by Plasma Treatment
5. Assessment of Fluoropolymers for use in Medical Devices
5.1 Introduction
5.2 Polymer characterization
5.3 Sterilization
5.4 Chemical resistance
5.5 Identification of extractable and leachable material
5.6 Biocompatibility
5.7 Shelf life and stability
6. Fluoropolymer Parts for Medical Devices
6.1 Microporous Membranes
6.2 Films and Sheets
6.3 Tubes (e.g. heat shrink)
6.4 Rods
6.5 Densified Films
7. Sterilization and Disinfection of Fluoropolymer Parts
7.1 Introduction
7.2 Definitions of Sterilization and Disinfection
7.3 Commercial Sterilization Methods
7.4 Advantages/disadvantages of Sterilization Methods
8. Introducers
8.1 Introduction to Access (access, needles, wire, catheter)
8.2 Introducer types
8.3 Micro-introducers
8.4 Peel-away introducer
8.5 Tracheal tube introducers
9. Sutures (Sina Ebnesajjad)
9.1 Introduction and Types (PTFE, PTFE Coated)
9.2 Mono and Multi Filament
9.3 Surgical
9.4 Dental
10. Lead Assemblies (Patents)
10.1 Introduction
10.2 Types
10.3 Cardiac Devices
11. Catheters (Ali Ashter)
11.1 Introduction and Types
11.2 Multilumen Catheters
11.3 Guiding Catheters (active or passive manipulation)
11.4 External Catheters
11.5 MicroCatheters
11.6 Catheter Balloons
12. Cardiovascular Devices
12.1 Vascular Implants
12.2 Covered Stents
12.3 Prosthetic Heart Valves
12.4 Vena Cava Filters
13. ePTFE Tissue Meshes
14. Arteriovenous ePTFE Grafts for Dialysis
14.1 Introduction and Types
14.1.1 Access
14.2 Dialysis
15. Ligament Reconstruction and Replacement
16. Other Devices
16.1 Coated wire
16.2 Closure Device
16.3 Microfiltration Media
16.4 PTFE Coated Electrodes
16.5 Electrosurgical blades
16.6 Forceps
16.7 Surgical (Suture) Needles
17.7.1 Tapered Needles
17.7.2 Cutting Suturing Needles
16.8 Hypodermic Needles
16.9 Mini-Vacutron
17. Radiopacity
17.1 Introduction
17.2 Fluoroscopy and X-ray Imaging
17.3 Additives to impart Radiopacity
17.4 Applications of Radiopaque Devices
Product details
Product details
- Edition: 1
- Latest edition
- Published: November 1, 2026
- Language: English
About the author
About the author
SE
Sina Ebnesajjad
Sina Ebnesajjad is the series editor of Plastics Design Library (PDL) published in the William Andrew imprint of Elsevier. This Series is a unique series, comprising technology and applications handbooks, data books and practical guides tailored to the needs of practitioners. Sina was the editor-in-chief of William Andrew Publishing from 2005 to 2007, which was acquired by Elsevier in 2009.
He retired as a Senior Technology Associate in 2005 from the DuPont fluoropolymers after nearly 24 years of service. Sina founded of FluoroConsultants Group, LLC in 2006 where he continues to work. Sina earned his Bachelor of Science from the School of Engineering of the University of Tehran in 1976, Master of Science and PhD from the University of Michigan, Ann Arbor, all in Chemical Engineering.
He is author, editor and co-author of fifteen technical and data books including five handbooks on fluoropolymers technology and applications. He is author and co-author of three books in surface preparation and adhesion of materials, two of which are in their second editions. Sina has been involved with technical writing and publishing since 1974.
His experiences include fluoropolymer technologies (polytetrafluoroethylene and its copolymers) including polymerization, finishing, fabrication, product development, failure analysis, market development and technical service. Sina holds six patents.
Affiliations and expertise
Fluoroconsultants Group, Chadds Ford, PA, USA