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Elsevier

Atomic Force Microscopy for Nanoscale Biophysics

From Single Molecules to Living Cells

  • 1st Edition - February 15, 2023
  • Latest edition
  • Author: Mi Li
  • Language: English

Atomic Force Microscopy for Nanoscale Biophysics: From Single Molecules to Living Cells summarizes the applications of atomic force microscopy for the investigation of biomol… Read more

Description

Atomic Force Microscopy for Nanoscale Biophysics: From Single Molecules to Living Cells summarizes the applications of atomic force microscopy for the investigation of biomolecules and cells. The book discusses the methodology of AFM-based biomedical detection, diverse biological systems, and the combination of AFM with other complementary techniques. These state-of-the-art chapters empower researchers to address biological issues through the application of atomic force microscopy. Atomic force microscopy (AFM) is a unique, multifunctional tool for investigating the structures and properties of living biological systems under aqueous conditions with unprecedented spatiotemporal resolution.

Key features

  • Summarizes the recent progress of atomic force microscopy in biomedical applications
  • Presents the methods and skills of applying atomic force microscopy
  • Aids researchers in investigating the nanoscale biophysics of diverse biological systems

Readership

Researchers in Biophysics, Cell Biology, Molecular Biology, Biochemistry, Material Science and related Biomedical fields. Graduate Students

Table of contents

1. Fundamentals and methods of AFM for biophysics

2. Imaging and force detection of DNA by AFM

3. High-resolution imaging and force spectroscopy of membrane proteins by AFM

4. Characterizing the nanostructures and properties of hydrogels by AFM

5. Detecting the behaviours of single virus by AFM

6. Nanoscale imaging and force probing of single microbial cells by AFM

7. Investigating the structures and mechanics of single animal cells by AFM

8. Combining AFM with complementary techniques: Hybrid AFM for biophysics

9. Conclusion and future perspectives

Product details

  • Edition: 1
  • Latest edition
  • Published: February 15, 2023
  • Language: English

About the author

ML

Mi Li

Mi Li PhD is a Full Professor at Shenyang Institute of Automation Chinese Academy of Sciences, Shenyang, China. Mi Li received the Ph.D. degree in 2015 from Shenyang Institute of Automation (SIA) Chinese Academy of Sciences, Shenyang, China, after which he continues academic career at SIA until now. Since 2009, Mi Li has been engaged in the studies of atomic force microscopy (AFM) and its biomedical applications ranging from molecules and organelles to cells as well as hydrogels, to reveal the role of micro/nanoscale biophysical cues in regulating life activities. Mi Li has conducted long-term visitor studies at The Ohio State University, Columbus, USA and ETH Zurich, Switzerland, respectively for academic research regarding AFM. Mi Li has won the National Natural Science Foundation of China for Excellent Young Scholars (2019), the IEEE Senior Member (2020), the Outstanding Doctoral Dissertation Award of Chinese Academy of Sciences (2016) and the Springer Theses (2018).
Affiliations and expertise
Professor, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, Liaoning province, China

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