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Elsevier

Ayurvedic Herbal Preparations in Neurological Disorders

  • 1st Edition - August 7, 2023
  • Latest edition
  • Editors: Murali Muralidhara, Padmanabhan S. Rajini
  • Language: English

Ayurvedic Herbal Preparations in Neurological Disorders provides a comprehensive and mechanistic understanding of the therapeutic potential of many ayurvedic herbal preparati… Read more

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Description

Ayurvedic Herbal Preparations in Neurological Disorders provides a comprehensive and mechanistic understanding of the therapeutic potential of many ayurvedic herbal preparations in disease management. Examining research data for evidence-based ayurvedic approaches, this volume begins with a focused introduction to major ayurvedic plants, discussing various mechanisms underlying their neuromodulatory potential in preclinical and clinical settings. Major subsets of ayurvedic plants are discussed, including Bacopa monnieri, Centella asiatica, Withania somnifera, and others. This volume outlines the importance of integrative approaches along with existing treatments in the intervention/management of Alzheimer’s disease, Parkinson’s disease, depressive mood disorders, epilepsy, schizophrenia, and more.

More than a mere compilation of studies, this volume identifies relevant gaps for future research avenues and encourages interdisciplinary collaboration and sharing of knowledge to together identify the most efficacious ayurvedic approaches. Highlighting recent developments (e.g., Ayurgenomics, Ayurahar) and other pertinent research for neuroprotection, this book is crucial for anyone researching or working in the field of neurological disorder treatment and prevention.

Key features

  • Provides a focused introduction to major Ayurvedic plants and their therapeutic potential in the management of neurodegenerative diseases
  • Discusses various mechanisms underlying the neuromodulatory potential of several ayurvedic herbal preparations in preclinical and clinical settings
  • Examines major subsets of ayurvedic plants (e.g., Bacopa monnieri, Centella asiatica, Withaniasomnifera, and others) and potential of several other plants in various neurological disorders
  • Outlines the importance of integrative approaches along with existing treatments in the intervention/management of depressive mood disorders, epilepsy, schizophrenia, and more
  • Highlights recent developments (e.g., Ayurgenomics, Ayurahar) and other pertinent research for neuroprotection

Readership

Neuroscientists, neurologists, researchers, biomedical scientists, pharmacologists, other clinicians, graduate students in biological and biomedical sciences

Table of contents

1. Ayurvedic herbal plants in Neurological disorders- status / Scope as golden nuggets

2. Overview of approaches in Ayurveda for neurological health and disorder

3. Polyherbalism - a panacea for management of neurodegenerative disorders

4. Insights on the neuroprotective strategies to alleviate neurodegenerative conditions: Role of Ayurvedic herbals and their bioactives: Clinical aspects

5. Multiple broad spectrum neuromodulatory effects of Bacopa monneri and Centella asiatica in preclinical/ clinical models: mechanistic considerations

6. Exploring the neuro-ameliorative propensity of Withania somnifera - Indian Ginseng

7. Indian Spices and their bioactives in Neurological disorders

8. Synaptic and mitochondrial alterations in Traumatic Brain Injury (TBI): Neuroprotective effects of phytochemicals/ herbal products.

9. Dietary Regulation of miRNAs involved in neurodegenerative diseases: Role of nutraceuticals/Ayurvedic herbals

10. Propensity of Ayurvedic herbs as modulators of Gut microbiome: Implications in Neurological disorders

11. Novel genetic modulators of neurodegenerative diseases as specific therapeutic agents

12. Therapeutic propensity of Natural polyphenols in Neurodegenerative disorders: Mechanistic insights

13. Phytochemicals for neurodegeneration and neuroinflammation: Medicine of the future or a mirage?

14. Plant-derived cognition enhancers for the management of Alzheimer's disease

15. Role of Ayurvedic herbs in the management of major depressive disorders(MDD)

16. Mass spectrometry-based approaches for identification of the molecular mechanism of action of Ayurvedic herbal medicines in PD

17. Insights into the efficacy of {i|Drosophila} as a predictive preclinical model to understand the mechanism of neuroprotection of Ayurvedic herbals

18. Caenorhabditis elegans models to study mode of action of Ayurvedic Nootropics at behavioral, cellular and molecular level

19. Utilization of Zebra fish as a preclinical model for obtaining insights on molecular mechanisms of neuroprotective role of ayurvedic herbal preparations

20. Acorus calamus in Neurological Disorders: A critical overview

21. Ayurvedic herbs and their potential as anti-aging therapies

22. Ayurvedic herbs and Yoga as immunomodulators

23. Yoga as a therapeutic intervention for the management of NDD

24. Benefits and concerns of nanotechnology in Ayurvedic medicine for neurological diseases.

25. Neuroprotective potential of plant-based bioactive polysaccharides: Molecular mechanisms and therapeutic advances

26. Ayurvedic herbals in Neurological disorders: Challenges, Limitations and Future perspectives

Review quotes

"…offers a compilation of chapters exploring the application of Ayurvedic medicine in addressing neurological disorders…. [A]ims to provide a thorough and detailed exploration of the utilization of Ayurvedic herbal preparations for managing neurological disorders....[A] valuable resource for advancing both research and practice in the field…. Color diagrams add a refreshing dimension to the reading experience, providing a welcome break from the monotony of black-and-white text…. [S]erves as an asset for both clinicians and researchers, offering up-to-date evidence pertinent to expanding treatments in neurological disease. [W]ell-structured format ensures easy access for clinicians seeking specific information while providing ample insight for researchers to guide future investigations....Highly recommended for those committed to the study of integrative medicine, particularly those intent to integrate proven herbal remedies into neurological disease treatments."— ©Doody’s Review Service, 2024, Paul Joseph Ratte, ND (Northwestern Health Sciences University)

Product details

  • Edition: 1
  • Latest edition
  • Published: August 9, 2023
  • Language: English

About the editors

MM

Murali Muralidhara

Dr. Muralidhara is Chief Scientist and former Head of the Department of Biochemistry and Nutrition at CSIR (Central Food Technological Research Institute). Having mentored 15 Doctoral candidates and 25 Master’s students, he has published 12 book chapters and 96 papers in peer-reviewed journals. A toxicologist by training, he has extensive research experience in the area of neurotoxicology with special reference to the neuromodulatory effects of Ayurvedic herbal plants, spice active principles, and nutraceuticals in cell models, Drosophila, and rodent models to understand underlyin molecular, biochemical, and oxidative stress mechanisms. He has worked primarily with three Ayurvedic plants (Bacopa monneri, Centella asiatica and Withania sominfera) in various preclinical models. His research has also looked at the modulatory potential of selected Ayurvedic herbal plants under experimentally induced hyperglycemic state in pregnant rats, and the protective effects of pro/prebiotics against toxicant-induced neuropathological conditions
Affiliations and expertise
Chief scientist (Retd), Dept of Biochemistry, CSIR- Central Food Technological Research Institute, Mysore, India

PR

Padmanabhan S. Rajini

Dr. Rajini is Senior Principal Scientist at CSIR (Central Food Technological Research Institute). She has pioneered in the area of pesticide toxicology, amelioration of toxicity by dietary components, and developed small animal models (C. elegans and Drosophila) for studying mechanistic toxicology. Her research focus has been the identification of novel food/plant-based components for prophylactic and ameliorative strategies to combat xenobiotic toxicity and ensuing disease progression. Her studies have addressed causes and probable mitigation of hyperglycemia, neurological disorders (Parkinson’s disease in particular), hypertension, and gastrointestinal disorders. Dr. Rajini has mentored 14 Doctoral candidates and 15 Master’s students and has published 5 book chapters and 64 papers in peer reviewed journals.
Affiliations and expertise
Senior Principal Scientist (Retd), Dept of Food Protectants & Infestation, Control, CSIR- Central Food Technological Research Institute, Mysore, India

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