Basic and Clinical Aspects of Veterinary Immunology

Contributors

Preface

Structural and Functional Characteristics of Immunoglobulins of the Common Domestic Species

I. Introduction

II. Classification of Immunoglobulins in Animal Species

III. Immunoglobulins in Fetal and Germfree Life

IV. Immunoglobulins in the Materno-Neonatal Relationship

V. Ontogeny, Transport, and Function of Intestinal Immunoglobulin

VI. Immunoglobulins in the Nasolacrimal Fluids

VII. Effector Mechanisms in Mucosal Immunity

References

Primary and Secondary Immune Deficiencies of Domestic Animals

I. Introduction

II. Overview of Immune Responses

III. Classification of Immune Deficiencies

IV. Detection and Characterization of Immune Deficiency Disorders

V. Immune Deficiencies of Domestic Animals

VI. Summary

References

Mechanisms of Immunity in Bacterial Infections

I. Parasitism and Pathogenicity

II. Mechanisms of Immunity

III. Antigenic Variation in Bacteria—Occurrence and Possible Contribution to Disease

References

The Immune System and Helminth Infection in Domestic Species

I. Introduction

II. Survival Mechanisms of Helminths in Their Hosts

III. Immunological Basis for Seasonal Variation in Gastrointestinal Nematode Burdens of Ruminants

IV. Protective Mechanisms in Helminth Infections

V. Physiological and Morphological Alterations of Nematodes Induced by Immune Reactions

VI. Trematodes

VII. Cestodes

VIII. Conclusion

References

Mechanisms of Viral Immunopathology

I. Introduction

II. Inflammatory Responses Mediated by T Cells

III. Immune Complex-Mediated Inflammatory Responses

IV. Allergic Immunopathologic Responses to Viruses

V. Immunologic Destruction of Virus-Infected Cells

VI. Initiation of Autoimmune Responses

VII. Initiation of Lymphoid Neoplasms

VIII. Direct Effects of Viruses on the Immune System

IX. Speculations

References

Immunology of a Persistent Retrovirus Infection—Equine Infectious Anemia

I. Introduction

II. Virus Characteristics

III. Virion Surface Glycoproteins

IV. Major Internal Virion Polypeptide (p29)

V. Viral-Infected Cell Membrane Antigen

VI. Anemia

VII. Immunosuppression

VIII. Viral Persistence

IX. Discussion

References

Immunology and Pathogenesis of African Animal Trypanosomiasis

I. Introduction

II. Trypanosomes

III. Immunology

IV. Pathogenesis

V. Conclusions

References

Tumor Immunology in Domestic Animals

I. Immune Surveillance

II. Tumor Antigens

III. Antitumor Immune Effector Mechanisms

IV. Immunotherapy of Cancer

V. Virus-Associated Tumors of Cats

VI. Avian Tumors Caused by Retroviruses

VII. Marek’s Disease

VIII. Bovine Leukosis

IX. Transmissible Venereal Sarcoma of Dogs

References

Applications of Transplantation Immunology in the Dog

I. Introduction

II. Current Status of Histocompatibility Testing in Dogs

III. Transplantation Immunology in Dogs

IV. New Applications of Transplantation Immunology in Dogs

V. Conclusions

References

Effects of Environmental Contaminants on the Immune System

I. Introduction

II. Detection of Altered Immune Function

III. Data Suggestive of Immune Interference

IV. Heavy Metals

V. Industrial Chemicals

VI. Pesticides

VII. Conclusions

References

Subject Index

Contents of Previous Volumes