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Bioactive Materials for Soft Tissue Regeneration

  • 1st Edition - June 4, 2024
  • Latest edition
  • Editors: Jiang Chang, Bin Li, Chengtie Wu
  • Language: English

Bioactive Materials for Soft Tissue Regeneration covers human tissue and its classification as hard tissue such as bone and soft tissue like skin, muscle, tendon, blood vessel, n… Read more

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Description

Bioactive Materials for Soft Tissue Regeneration covers human tissue and its classification as hard tissue such as bone and soft tissue like skin, muscle, tendon, blood vessel, nerve etc., and including organs such as heart, liver, lung. Regenerative medicine deals with both hard tissue and soft tissue regeneration and is one of the most important part of the modern medicine with significant clinical needs including general surgery, plastic surgery, burn and wound healing, cardiovascular disease treatments. Based on the authors’ previous research and review of the international advances in hard tissue regeneration, this book focuses on the hard tissue regeneration using bioactive materials.

Sections cover biomaterials for entire human tissue regeneration, which is key important for research and development in the field of biomedical engineering and the medical device industry. Readers will find this to be a comprehensive review of the most updated advances of the research in bioactive materials for soft tissue repair and regeneration, along with perspectives for future directions of research and development in this field.

Key features

  • Covers recent development of bioactive materials for soft tissue regeneration
  • Provides basic principles for design of bioactive materials for tissue regeneration
  • Includes future perspectives surrounding the development of bioactive materials that will be valuable to the readers

Readership

Academics and researchers in materials science, biomedical engineering and engineering, R&D scientists working in biomedical and pharmaceutical industries

Table of contents

1. Introduction biomaterials


2. Biological effect of materials chemistry on soft tissue regeneration

2.1. Introduction 2.2. Fabrication of biomaterials with different chemical composition 2.2.1. Polymer materials with bioactive modification 2.2.2. Bioceramics and bioactive glasses with different chemical composition 2.3. Bioactive effect of materials with different chemical composition 2.3.1. Regulation of cellular activity by biomaterials with different chemical composition 2.3.1.1. Regulation of stem cells by biomaterials with different chemical composition 2.3.1.2. Regulation of tissue specific cells by biomaterials with different chemical composition 2.3.1.3. Regulation of macrophages by biomaterials with different chemical composition 2.3.2. Soft tissue regeneration regulated by biomaterials with different chemical composition 2.4. Multi-functional biomaterials with different functional components for soft tissue regeneration 2.5. Concluding remarks References


3. Biological effect of materials structure on soft tissue regeneration

3.1. Introduction 3.2. Fabrication of biomaterials with multi-scale structure 3.2.1. Fabrication of biomaterials with micro-scale structure 3.2.2. Fabrication of biomaterials with nano-scale structure 3.3. Effect of materials structure on tissue regeneration 3.3.1. Effect of microstructure on cellular activity 3.3.1.1 Regulation of stem cells by materials structure 3.3.1.2 Regulation of tissue specific cells by materials structure 3.3.1.3. Regulation of macrophages by materials structure 3.4. Effect of multi-scale structure on tissue regeneration 3.5. Concluding remarks References


4. Biological effects of material mechanics and its application in soft tissue regeneration

4.1 Introduction 4.2. Biomaterials with adjustable mechanics 4.2.1. 2D materials 4.2.2. 3D materials 4.2.3 Gradient materials 4.3. Effect of material mechanics on cell adhesion, spreading, migration and proliferation 4.3.1 Stiffness 4.3.2 Viscoelasticity 4.4. Effect of material mechanics on cell differentiation 4.4.1 Stiffness 4.4.2 Viscoelasticity 4.5. Molecular basis of cellular modulation by mechanics 4.5.1 Matrix stiffness and viscoelasticity 4.5.2 Other modulation factors through mechanotransduction (Topography, chemical composition, mechanical stress?) 4.6. Regeneration of soft tissues by material mechanics 4.6.1 Cartilage 4.6.2 Nerve 4.6.3 Blood vessel 4.6.4 Intervertebral disc 4.6.4 Other tissues (skin, tendon/ligament…) 4.7. Concluding remarks References

Product details

  • Edition: 1
  • Latest edition
  • Published: June 14, 2024
  • Language: English

About the editors

JC

Jiang Chang

Jiang Chang is a professor at the Shanghai Institute of Ceramics, Chinese Academy of Sciences, China, and an Associate of the University of Manitoba Transport Institute. He is one of the leading young scholars worldwide in the field of transport economics and policy in the sectors of aviation, rail and maritime. He has received numerous prestigious accolades such as the Associates’ Achievement Award for Outstanding Business Research. His research focuses on bioactive materials for tissue regeneration and tissue engineering and the mechanisms of the interaction between biomaterials and cells. Professor Chang has over 300 scientific papers published in international peer-reviewed scientific journals and 70 patents in the field of biomedical materials.
Affiliations and expertise
Assistant Professor, Transport and Supply Chain Management, University of Manitoba, Canada

BL

Bin Li

Today, Dr. Li’s research is focused on statistics and machine learning. He has published >75 peer reviewed research papers with >1,300 citations of his work.
Affiliations and expertise
Department of Experimental Statistics Louisiana State University Baton Rouge, Louisiana, USA

CW

Chengtie Wu

Prof. Chengtie Wu is now working at Shanghai Institute of Ceramics, Chinese Academy of Sciences (SIC, CAS). He completed his Ph.D in 2006, and then he worked in the University of Sydney, Queensland University of Technology and Dresden University of Technology where he was awarded Vice-Chancellor Research Fellow and Alexander von Humboldt Fellow. In 2012, Dr Wu has been recruited to work in SIC, CAS. Prof Wu’s research focuses on 3D Printing of Bioactive Inorganic Materials for Tissue Engineering. Up to now, Prof Wu has published more than 200 SCI peer-review journal papers. He is now the Associate editors for “Applied Materials Today” and “Journal of Inorganic Materials”, as well as the editorial board member of “Acta Biomaterialia”.
Affiliations and expertise
Shanghai Institute of Ceramics, Chinese Academy of Sciences (SIC, CAS), Shanghai, People's Republic of China

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