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Blood Banking and Transfusion Medicine

Basic Principles and Practice

  • 2nd Edition - October 18, 2006
  • Latest edition
  • Authors: Christopher D. Hillyer, Leslie E. Silberstein, Paul M. Ness, Kenneth C. Anderson, John D. Roback
  • Language: English

Ever since the discovery of blood types early in the last century, transfusion medicine has evolved at a breakneck pace. This second edition of Blood Banking and Transfusion… Read more

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Description

Ever since the discovery of blood types early in the last century, transfusion medicine has evolved at a breakneck pace. This second edition of Blood Banking and Transfusion Medicine is exactly what you need to keep up. It combines scientific foundations with today's most practical approaches to the specialty. From blood collection and storage to testing and transfusing blood components, and finally cellular engineering, you'll find coverage here that's second to none. New advances in molecular genetics and the scientific mechanisms underlying the field are also covered, with an emphasis on the clinical implications for treatment. Whether you're new to the field or an old pro, this book belongs in your reference library.

Key features

  • Integrates scientific foundations with clinical relevance to more clearly explain the science and its application to clinical practice.
  • Highlights advances in the use of blood products and new methods of disease treatment while providing the most up-to-date information on these fast-moving topics

Readership

Hematologists

Table of contents

Part I. History


1. A Brief History of Blood Transfusion

Part II. Blood Banking

A. Immunohematology

i. Basic Principles


2. Principles of the Immune System Central to Transfusion Medicine

3. Principles of the Complement System Central to Transfusion Medicine

4. Principles of Red Blood Cell Allo- and Autoantibody Formation and Function

ii. Red Blood Cell, Platelet and Leukocyte Antigens and Antibodies


5. Membrane Blood Group Antigens and Antibodies

6. ABO and Related Antigens and Antibodies

7. Rh, Kell, Duffy, and Kidd Antigens and Antibodies

8. Other Blood Group Antigens and Antibodies

9. Human Platelet Antigens and Antibodies

10. HLA and Granulocyte Antigens and Antibodies

B. Blood Donation, Manufacturing, Testing and Storage


11. Blood Donation and Collection

12. Blood Manufacturing: Component Preparation, Storage and Transportation

13. Red Blood Cell Metabolism During Storage: Basic Principles and Practical Aspects

14. Infectious Disease Testing: Basic Principles and Practical Aspects

C. Regulatory, Quality and Legal Principles


15. Regulatory Principles and Issues Central to Blood Banking and Transfusion Medicine

16. Quality Assurance, Control and Improvement and Accreditation

17. Legal Principles and Issues Central to Transfusion Medicine

D. Specific Blood Components


18. Packed Red Blood Cell and Related Products

19. Fresh Frozen Plasma and Related Products

20. Cryoprecipitate and Related Products

21. Albumin

22. IVIg and Derivatives

23. Platelets and Related Products

24. Granulocytes

25. Coagulation Factor Preparations

E. Special Processes and Products


26. Leukocyte Reduced Products

27. Virus Safe Products: Pathogen Reduction and Inactivation

28. Irradiated Products

29. Washed and/or Volume Reduced Blood Components

30. Blood Management: Conservation, Salvage and Alternatives to Allogeneic Transfusion

31. Blood Substitutes: Basic Principles and Pracitcal Aspects

III. Transfusion Medicine

A. Transfusion in Specific Clinical Settings


32. Red Blood Cell Transfusion: Surgical and Traumatic Blood Loss and Anemia

33. Post-Transfusion Red Blood Cell and Platelet Survical and Kinetics: Basic Principles and Practical Aspects

34. Transfusion of the Patient with Congenital Coagulation Defects

35. Transfusion of the Patient with Acquired Coagulation Defects

36. Obstetric and Intrauterine Transfusion

37. Transfusion of the Neonates and Pediatric Patients

38. Transfusion of the Hemoglobinopathy Patient

39. Transfusion to Bone Marrow or Solid Organ Transplant Recipients

40. Transfusion of the Platelet Refractory Patient

41. Transfusion of the Patient with an Autoimmune Hemolytic Anemia

42. Transfusion in Economically-Restricted Countries and Developing Countries

B. Complications of Transfusion

i. Infectious Complications


43. Hepatitis A, B, and Non-A, Non-B, Non-C Viruses

44. Hepatitis C

45. HIV, HTLV, and Other Retroviruses

46. Human Herpesvirus Infections

47. Bacterial Infections: Bacterial Contamination, Testing and Post Transfusion Complications

48. Other Viral, Bacterial and Prion-Based Infectious Complications

ii. Non-Infectious Complications


49. Acute and Delayed Hemolytic Transfusion Reactions

50. Febrile, Allergic, and Other Noninfectious Transfusion Reactions

51. Transfusion-Related Acute Lung Injury

52. Transfusion-Related Immunomodulation

53. Post-Transfusion Engraftment Syndromes: Microchimerism and TA-GvHD

C. Therapeutic Apheresis


54. Therapeutic Apheresis: Basic Principles and Practical Aspects

55. Therapeutic Plasma Exchange

56. Therapeutic Cytapheresis

D. Cellular Therapies and Tissue Banking


57. The Role of Transfusion Medicine in Cellular Therapies

58. Bone Marrow and Peripheral Blood Stem Cells: Collection, Processing and Transfusion

59. Umbilical Cord Blood Stem Cells: Collection, Processing and Transfusion

60. Mononuclear Cell-Based Preparations

61. Tissue Banking in the Hospital Setting

Product details

  • Edition: 2
  • Latest edition
  • Published: October 18, 2006
  • Language: English

About the authors

CH

Christopher D. Hillyer

Christopher D. Hillyer, MD, is President and CEO of New York Blood Center and Professor, Department of Medicine, Weill Cornell Medical College, New York, NY. Previously, he was the tenured, endowed Distinguished Service Professor, Department of Pathology and Laboratory Medicine, Emory University School of Medicine and served as director of the Emory Center for Transfusion and Cellular Therapies with responsibility for all aspects of clinical and academic transfusion medicine at Emory’s seven principle hospitals. Dr. Hillyer is an editor of twelve textbooks in transfusion medicine, author of over 160 articles pertaining to transfusion, human immunodeficiency virus, and herpes viruses, most notably cytomegalovirus. Nationally recognized as an expert in hematology and blood transfusion, Dr. Hillyer is also a past-president, board of directors of AABB and a former trustee of the National Blood Foundation. Dr. Hillyer has been awarded many million dollars in research funding from the National Institutes of Health, the Centers for Disease Control and Prevention and other agencies. He was an associate editor of Transfusion and serves on several other editorial boards. Dr. Hillyer was formally recognized for his work in Africa as part of the AABB/Emory cooperative agreement from the President’s Emergency Plan For AIDS Relief (PEPFAR), and is a recipient of two Tiffany Awards from the American Red Cross where he also served as a medical director and a member of their national Medical Advisory Board. He also received the 2014 Emily Cooley Award from AABB for his “significant commitment and contributions to the field of transfusion medicine through extensive teaching, mentoring and professional leadership, and the countless clinical, scientific and innovative resource materials he has created to educate others”. He is a co-founder of Transfusion & Transplantation Technologies, Inc (3Ti) and holds over 20 patents or patents pending. Dr. Hillyer is board certified in transfusion medicine, hematology, medical oncology and internal medicine. He received his BS from Trinity College, and his MD from the University of Rochester School of Medicine, with postgraduate training and fellowships in hematology-oncology, transfusion medicine and bone marrow transplantation at Tufts-New England Medical Center.
Affiliations and expertise
President and Chief Executive Officer, New York Blood Center and Professor, Department of Medicine, Weill Cornell Medical College, New York, NY, USA

LS

Leslie E. Silberstein

Affiliations and expertise
Director, Transfusion Medicine, Professor of Pathology, Boston Children’s Hospital, Harvard Medical School, Boston, Massachussetts

PN

Paul M. Ness

Affiliations and expertise
Director, Transfusion Medicine Division, Johns Hopkins Medical Institutions; Professor, Pathology, Medicine, and Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA

KA

Kenneth C. Anderson

Affiliations and expertise
Chief, Division of Hematologic Neoplasia; Director, Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute; Kraft Family Professor of Medicine, Joint Program in Transfusion Medicine, Harvard Medical School, Boston, MA

JR

John D. Roback

Affiliations and expertise
Associate Director, Transfusion Medicine Program; Associate Professor, Department of Pathology and Laboratory Medicine, Emory University, School of Medicine, Atlanta, GA, USA

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