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Elsevier

Cellular, Molecular, Physiological, and Behavioral Aspects of Traumatic Brain Injury

  • 1st Edition - May 10, 2022
  • Latest edition
  • Editors: Rajkumar Rajendram, Victor R. Preedy, Colin R. Martin
  • Language: English

Traumatic brain injury has complex etiology and may arise as a consequence of physical abuse, violence, war, vehicle collisions, working in the construction industry, and sp… Read more

Description

Traumatic brain injury has complex etiology and may arise as a consequence of physical abuse, violence, war, vehicle collisions, working in the construction industry, and sports. Cellular, Molecular, Physiological, and Behavioral Aspects of Traumatic Brain Injury will improve readers’ understanding of the detailed processes arising from traumatic brain injury. Featuring chapters on neuroinflammation, metabolism, and psychology, this volume discusses the impact of these injuries on neurological and body systems to better understand underlying pathways. This book will be relevant for neuroscientists, neurologists, clinicians, and anyone working to better understand traumatic brain injury.

Key features

  • Summarizes the neuroscience of traumatic brain injury, including cellular and molecular biology
  • Contains chapter abstracts, key facts, dictionary, and summary points to aid in understanding
  • Features chapters on signaling and hormonal events
  • Includes plasticity and gene expression
  • Examines health and stress behaviors after traumatic brain injury

Readership

Neuroscientists, neurologists, clinicians, health scientists, public health workers, doctors, and research scientists. Undergraduates, postgraduate, lecturers and academic professors

Table of contents

I. Setting The Scene and Introductory Chapters

1. Fall-related traumatic brain injuries: The role of the neck
Jacob Sosnoff and Tobia Zanotto

2. The implications of sex and gender in traumatic brain injury
Tatyana Mollayeva

3. Concussion and sports injuries the role of repetitive head injury exposure
Brian D. Stemper

4. Traumatic brain injury and molecular biology: a new narrative
Asma Akbar Ladak, Sarosh Irfan Madhani, Fatima Gauhar, Kiran Aftab, Fatima Mubarak and Syed Ather Enam

5. Features of Decompressive Craniectomy in Traumatic Brain Injury: History, Effects, Management and New Trends
Zefferino Rossini

6. Management of Traumatic Brain Injury in Accordance With Contemporary Guidelines: Treatment, Monitorization and Thresholds
Gregory W.J. Hawryluk and Buse Sarigul

II. Cellular and Molecular Aspects of Traumatic Brain Injury



7. Neuroinflammatory responses in traumatic brain injury
J Narayanan, T. Tamilanban, V. Chitra and M.K Kathiravan

8. Seizures in traumatic brain injury: a focus on cellular aspects
Thara Tunthanathip

9. Linking traumatic brain injury, neural stem and progenitor cells
Li Cai

10. The microglia in traumatic brain injury
Ramesh Raghupathi, Dana Lengel and JIMMY HUH

11. Dendritic spine plasticity and traumatic brain injury
Ye Xiong, Asim Mahmood and Michael Chopp

12. Immune response and traumatic brain injury
Sandy Shultz and Mujun Sun

13. The adaptive immune system in traumatic brain injury: a focus on T and B lymphocytes
Maria Daglas, Robert Medcalf and Maithili Sashindranath

14. Regulatory T cells and traumatic brain injury
Michael K.E. Schäfer

15. The role of prokineticin 2 in traumatic brain injury
Marimelia A. Porcionatto

16. Na+/K+- ATPase activity and traumatic brain injury
L.F.F. Royes

17. Pyruvate dehydrogenase complex enzymes, metabolic enzymes and energy derangement in traumatic brain injury
Giacomo Lazzarino, Patrick O’Halloran, Valentina Di Pietro, Renata Mangione, Barbara Tavazzi, Angela Maria Amorini, giuseppe lazzarino and Stefano Signoretti

18. Angiopoietin-1/Tie-2 and traumatic brain injury
Yutaka Koyama and Shotaro Michinaga

19. Brain microdialysis and applications to drug therapy in severe traumatic brain injury
N. Ketharanathan, U. Rohlwink, A. Figaji, Enno Wildschut, D. Tibboel and Elizabeth Cunera maria de Lange

20. Comparing radiation and traumatic brain injuries: new narrative
Steve Kornguth

21. Electrolytes and traumatic brain injury: a focus on sodium
Yvonne Lui and Hemal Grover

22. WNT genes and their role in traumatic brain injury
Linyi Chen, Min-Zong Liang and Chu-Yuan Chang

III. Physiological and Metabolic Effects



23. Circuit Reorganization After Diffuse Axonal Injury: Utility of the Whisker Barrel Circuit
Theresa Currier Thomas and Gokul Krishna

24. Neuroendocrine Abnormalities Following Traumatic Brain Injury
Jehane Dagher and Benjamin Green

25. Thyroid hormone actions in the setting of traumatic brain injury
Adomas Bunevicius

26. Testosterone: features and role in treating traumatic brain injury
L. Portela

27. The rate of empty sella (ES) in traumatic brain injury: links with endocrine profiles
Fausto Fama, Alessandro Sindoni, Ulla Feldt-Rasmussen, Salvatore Benvenga and Marianne Klose

28. Traumatic brain injury. Interrelationship with sleep
Rachel Rowe

29. Pubety and traumatic brain injury
Rachel Rowe

30. Role of endocannabinoids in the escalation of alcohol use following traumatic brain injury
Patricia E. Molina, Zachary Stielper, Scott Edwards and Nicholas Gilpin

31. Imaging connectivity and functional brain networks in mild traumatic brain injury
Maria M. D'Souza, Mukesh Kumar, Jeanne D'Souza, Prabhjot Kaur and Pawan Kumar

32. Multi-shell diffusion MR imaging and brain microstructure after mild traumatic brain injury: A focus on working memory
Sohae Chung, Els Fieremans, Joseph Rath and Yvonne Lui

33. Monitoring real-time changes in physiology: impact of pediatric traumatic brain injury
Brian Appavu

34. Blood gasses, arterial and end-tidal carbon dioxide in traumatic brain injury
Jen-Ting Yang, Chun-Yu Wu, and David R. Wright

35. Disturbances of cerebral microcirculation in traumatic brain injury: the role of changes in microcirculatory biomarkers
Alexey O. Trofimov

IV. Behavioural and Psychological Effects



36. Social cognition in traumatic brain injury
Philippe Allain

37. Physical exercise: effects on cognitive function after traumatic brain injury
Margalida Coll, Laura Amorós-Aguilar, David Costa-Miserachs, Isabel Portell-Cortés and Meritxell Torras-Garcia

38. Linking cognitive function, diffuse traumatic brain injury and dementia
Lyndsey Collins-Praino

39. Neuropsychological Functioning of Children and Youth after Traumatic Brain Injury
Paula Karina Perez-Delgadillo, Daniela Ramos-Usuga, Nini Lucia Muñoz-Perez and Juan Arango Arango-Lasprilla

40. Behavioral effects of traumatic brain injury: use of guanosine
Felix Alexandre Antunes Soares and Fernando Dobrachinski

41. Recognizing emotions and effects of traumatic brain injury
Alessia Celeghin, Ylenia Camassa Nahi, Blanca Tasso and Olga Dal Monte

42. Cognitive Communication Connections and Higher-Level Language with Traumatic Brain Injured Population
J. Koebli

43. Self-awareness after severe traumatic brain injury: from impairment of Self-awareness to psychological adjustment
U. Bivona, Susanna Lucatello and Alberto Costa

44. Disentangling antecedents from consequences of traumatic brain injury: The need for prospective longitudinal studies
Sheilagh Hodgins and G. Guberman

45. Linking sleeping patterns and quality of life in childhood traumatic brain injury
Edith Botchway

　

Product details

  • Edition: 1
  • Latest edition
  • Published: May 10, 2022
  • Language: English

About the editors

RR

Rajkumar Rajendram

Dr Rajkumar Rajendram is a clinician scientist with a focus on internal medicine, anaesthesia, intensive care and peri-operative medicine. He graduated with distinctions from Guy’s, King’s and St. Thomas Medical School, King’s College London in 2001. As an undergraduate he was awarded several prizes, merits and distinctions in pre-clinical and clinical subjects.

Dr Rajendram began his post-graduate medical training in general medicine and intensive care in Oxford. He attained membership of the Royal College of Physicians (MRCP) in 2004 and completed specialist training in acute and general medicine in Oxford in 2010. Dr Rajendram subsequently practiced as a Consultant in Acute General Medicine at the John Radcliffe Hospital, Oxford.

Dr Rajendram also trained in anaesthesia and intensive care in London and was awarded a fellowship of the Royal College of Anaesthetists (FRCA) in 2009. He completed advanced training in regional anaesthesia and intensive care. He was awarded a fellowship of the Faculty of Intensive Care Medicine (FFICM) in 2013 and obtained the European diploma of intensive care medicine (EDIC) in 2014. He then moved to the Royal Free London Hospitals as a Consultant in Intensive Care, Anaesthesia and Peri-operative Medicine. He has been a fellow of the Royal College of Physicians of Edinburgh (FRCP Edin) and the Royal College of Physicians of London (FRCP Lond) since 2017 and 2019 respectively. He is currently a Consultant in Internal Medicine at King Abdulaziz Medical City, National Guard Heath Affairs, Riyadh, Saudi Arabia.

Dr Rajendram’s focus on improving outcomes from Coronavirus Disease 2019 (COVID-19) has involved research on point of care ultrasound and phenotypes of COVID-19. Dr Rajendram also recognises that nutritional support is a fundamental aspect of medical care. This is particularly important for patients with COVID-19. As a clinician scientist he has therefore devoted significant time and effort into nutritional science research and education. He is an affiliated member of the Nutritional Sciences Research Division of King’s College London and has published over 400 textbook chapters, review articles, peer-reviewed papers and abstracts.

Affiliations and expertise
Consultant, Medical Protocol Department, King Abdulaziz Medical City, Ministry of National Guard Heath Affairs, Riyadh, Saudi Arabia

VP

Victor R. Preedy

Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRSC, FRCPath graduated with an Honours Degree in Biology and Physiology with Pharmacology. After gaining his University of London PhD, he received his Membership of the Royal College of Pathologists. He was later awarded his second doctorate (DSc), for his contribution to protein metabolism in health and disease. He is Professor of Clinical Biochemistry (Hon) at King’s College Hospital and Emeritus Professor of Nutritional Biochemistry at King’s College London. He has Honorary Professorships at the University of Hull, and the University of Suffolk. Professor Preedy was the Founding Director and then long-term Director of the Genomics Centre at King’s College London from 2006 to 2020. Professor Preedy has been awarded fellowships of the Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health, the Royal Society for Public Health, the Royal Society of Chemistry and the Royal Society of Medicine. He carried out research when attached to the National Heart Hospital (part of Imperial College London), The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with international research groups in Finland, Japan, Australia, USA, and Germany. To his credit, Professor Preedy has published over 750 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and edited books.
Affiliations and expertise
Professor, Department of Clinical Biochemistry, King’s College Hospital, London, UK; Emeritus Professor, Faculty of Life Sciences and Medicine, King’s College London, UK; Visiting Professor, University of Hull, UK

CM

Colin R. Martin

Colin R. Martin RN, BSc, MSc, PhD, MBA, YCAP, FHEA, C.Psychol, AFBPsS, C.Sci is Professor of Clinical Psychobiology and Applied Psychoneuroimmunology and Clinical Director of the Institute of Health and Wellbeing at the University of Suffolk, UK. He is a Chartered Health Psychologist and a Chartered Scientist. He also trained in analytical biochemistry, this aspect reflecting the psychobiological focus of much of his research within mental health. He has published or has in press well over 300 research papers and book chapters. He is a keen book author and editor having written and/or edited more than 50 books. These outputs include the prophetic insight into the treatment of neurological disease, Handbook of Behavior, Food and Nutrition (2011), Nanomedicine and the Nervous System (2012), Oxidative Stress and Dietary Antioxidants in Neurological Disease (2020), Zika Virus Impact, Diagnosis, Control and Models (2021), Factors Affecting Neurodevelopment: Genetics, Neurology, Behavior and Diet (2021), Diagnosis and Treatment of Spinal Cord Injury (2022), The Neurobiology, Physiology, and Psychology of Pain (2022) and The Handbook of Lifespan Cognitive Behavioral Therapy: Childhood, Adolescence, Pregnancy, Adulthood, and Aging (2023). Professor Martin is particularly interested in all aspects of the relationship between underlying physiological substrates and behavior, particularly in how these relationships manifest in both acute and chronic psychiatric disorder. He has published original research germane to significant mental health disorders including the areas of schizophrenia, anxiety, depression, self-esteem, alcohol and drug dependency, high secure forensic mental health and personality disorder. He has a keen interest in the impact of postviral illness and is actively involved in clinical research post-Covid pandemic and in particular, the impact of Long Covid on psychological, neurological, physiological and social functioning. He is involved in collaborative International research with many European and Non-European countries.
Affiliations and expertise
Visiting Professor of Perinatal Wellbeing, Institute for Health and Wellbeing, University of Suffolk, Ipswich, UK

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