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Chesley's Hypertensive Disorders in Pregnancy

  • 3rd Edition - April 16, 2009
  • Editors: James M. Roberts, Gary F. Cunningham, Marshall D. Lindheimer
  • Language: English

Hypertensive disorders remain one the major causes of maternal and fetal morbidity and death. It is also a leading cause of preterm birth now known to be a risk factor in remote… Read more

Description

Hypertensive disorders remain one the major causes of maternal and fetal morbidity and death. It is also a leading cause of preterm birth now known to be a risk factor in remote cardiovascular disease. Despite this, the hypertensive disorders remain marginally studied, and their management is commonly controversial. Chesley’s Hypertensive Disorders in Pregnancy remains one of the beacons to guide this field, recognized for its uniqueness and utility. The Third Edition continues this tradition, focusing on prediction, prevention, and management for clinicians, and is an essential reference text for clinical and basic investigators alike. Differing from other texts devoted to preeclampsia, it covers the whole gamut of high blood pressure, not just preeclampsia.

Readership

The audience for this book remains wide and includes a) Obstetricians, especially those who care for high risk pregnancies (Maternal Fetal Medicine sub-specialists); b) Internists, primarily nephrologists, cardiologists, and any consultants who focus on either hypertensive disorders, or a new field dubbed "obstetric medicine". It is especially relative to growing groups from a variety of disciplines who are involved in preeclampsia research, including cardiovascular, renal, and placenta- focused basic studies, as well as clinical trials. For example the American and International Societies of Nephrology, as well as the American Society of Hypertension have or will highlight symposia relating to progress and management of hypertension in pregnancy. This trend will surely continue with updates at the time of the books publication.

Table of contents


Chapter 1 Introduction, History, Controversies, and Definitions

Chapter 2 The Clinical Spectrum of Preeclampsia

Chapter 3 Epidemiology of Pregnancy-Related Hypertension

Chapter 4 Genetic Factors in the Etiology of Preeclampsia/Eclampsia

Chapter 5 The Placenta in Normal Pregnancy and Preeclampsia

Chapter 6 Angiogenesis and Preeclampsia

Chapter 7 Metabolic Syndrome and Preeclampsia

Chapter 8 Immunology of Normal Pregnancy and Preeclampsia

Chapter 9 Endothelial Cell Dysfunction and Oxidative Stress

Chapter 10 Animal Models

Chapter 11 Tests to Predict Preeclampsia

Chapter 12 Prevention of Preeclampsia and Eclampsia

Chapter 13 Cerebrovascular (Patho)Physiology in Preeclampsia/Eclampsia

Chapter 14 Cardiovascular Alterations in Normal and Preeclamptic Pregnancy

Chapter 15 Normal and Abnormal Volume Homeostasis

Chapter 16 Agonistic Autoantibody-Mediated Disease

Chapter 17 The Kidney in Normal Pregnancy and Preeclampsia

Chapter 18 Platelets, Coagulation, and the Liver

Chapter 19 Chronic Hypertension and Pregnancy

Chapter 20 Antihypertensive Treatment

Chapter 21 Management


Review quotes

Reviews of the second edition:
"Preeclampsia remains a lethal enigma of pregnancy. Encompassing more than just hypertension, it can include abnormalities of platelet behavior and clotting mechanisms and of endothelial, hepatic, and renal function. The first edition of Leon Chesley's Hypertensive Disorders in Pregnancy (1978) was a scholarly monograph, written by a scientist with a passionate interest in the condition. Since then, the number of maternal deaths from preeclampsia and eclampsia per million pregnancies has been halved in developed countries. Nevertheless, preeclampsia, together with eclampsia, remains one of the two most frequently cited causes of maternal death in the West. The second edition is a multiauthored book. The three editors are researchers who have made a particular effort to achieve a degree of homogeneity in the presentation. The contents are divided into six main sections, each overseen by one of the three editors. Each chapter is also coauthored by one of the editors, which has resulted in coherence in the writing among chapters. Most of the chapters begin with a paragraph about how the topic was considered by Chesley that emphasizes the forward-looking and comprehensive nature of his interest...This book is an authoritative compilation of knowledge in the area, with many references from the second half of the 1990s. It should certainly be in the library of every academic department." —The New England Journal of Medicine

"This book is useful for investigators and physicians in the field of hypertension in pregnancy. It is a well-documented book and each chapter is written by an expert in the field. 4 stars!"—Doody

Product details

About the editors

JR

James M. Roberts

Dr. Roberts’ research is interdisciplinary and involves fundamental, clinical, behavioral and epidemiological studies. He has been involved in several seminal studies of preeclampsia including the recognition of preeclampsia as involving endothelial dysfunction and being more than hypertension in pregnancy. He currently is involved in global health research as part of the Global Pregnancy Collaboration, a consortium of 40 centers world-wide that facilitates collaborative research. He is a co-investigator on studies in Brazil and South Africa. He chaired the ACOG Hypertension Task Force and was co-chair of the NHLBI NIH workshop on research on pregnancy hypertension.
Affiliations and expertise
Senior Scientist, Magee Women’s Research Institute, Professor, Obstetrics, Gynecology, Reproductive Sciences, Epidemiology, and Clinical and Translational ResearchUniversity of Pittsburgh, Pittsburgh, PA, USA

GC

Gary F. Cunningham

F. Gary Cunningham, MD is holder of the Miguel and Beatrice Distinguished Chair of Obstetrics and Gynecology at the University of Texas Southwestern Medical Center. He is also chair emeritus of the Department of Obstetrics and Gynecology, having served in that position for 22 years. Dr. Cunningham received his MD degree from the Louisiana State University School of Medicine and completed a residency in Obstetrics and Gynecology at Charity Hospital of New Orleans. Following this, he completed a fellowship in Maternal-Fetal Medicine at UT Southwestern and Parkland Hospital in Dallas, Texas. His early career was influenced by Dr. Jack Pritchard, and together they performed extensive clinical and laboratory research in preeclampsia and eclampsia, coagulopathies and other hematological complications of pregnancy, as well as a myriad of medical and surgical disorders complicating pregnancy. He has served as an examiner for the American Board of Obstetrics and Gynecology, served as tor for an NIH consensus conference, and is a member of the Society for Maternal-Fetal Medicine, Society for Gynecologic Investigation, and the American Gynecological and Obstetrical Society. Dr. Cunningham has served as senior editor of the 18th through 24th editions of Williams Obstetrics.
Affiliations and expertise
Professor and Beatrice and Miguel Elias Distinguished Chair in Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, USA

ML

Marshall D. Lindheimer

Dr. Marshall Lindheimer, a professor (emeritus) of Medicine, Obstetrics & Gynecology, and Clinical Pharmacology at the University of Chicago is a longtime admirer and was a longtime friend of the late Leon Chesley. Chief Editor of the second and third editions of this text and leader of the search for its current chief editor, Dr. Lindheimer prefers to be called “editor emeritus” despite continuing to comment and publish in the area of the hypertension and renal disease in pregnancy. His CV contains over 400 publications including a monograph, other edited texts, reviews, text chapters and articles devoted to both basic and clinical research. Boarded in Internal Medicine and Nephrology, he is the recipient of many awards and honors that include an honorary membership in the Society of Maternal Fetal Medicine and an ad eundem of the Royal College of Obstetrics and Gynecology London. He has received an Honoris Causa degree from Bern University, the Chesley award from the International Society for the Study of Hypertension in Pregnancy, the Belding Scribner Award from the American Society of Nephrology and the Joseph Bolivar DeLee Humanitarian award from the Board of Directors at Lying-in Hospital, Chicago. Both the National Kidney Foundation of Illinois and the Preeclampsia Foundation have honored him as well. Of note on his wall is a congratulatory letter from President Obama, recognizing his accomplishments in regard to the health of pregnant women and their unborn children.
Affiliations and expertise
Professor Emeritus, Department of Obstetrics and Gynecology and Medicine, and the Committee on Clinical Pharmacology, The University of Chicago, IL, USA

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