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Elsevier

Clinical Aspects of Multiple Sclerosis Essentials and Current Updates

  • 1st Edition - January 13, 2024
  • Latest edition
  • Editors: Shitiz Sriwastava, Evanthia Bernitsas
  • Language: English

Clinical Aspects of Multiple Sclerosis Essentials and Current Updates offers readers a comprehensive and up-to-date analysis of multiple sclerosis (MS) and its related disorders,… Read more

Description

Clinical Aspects of Multiple Sclerosis Essentials and Current Updates offers readers a comprehensive and up-to-date analysis of multiple sclerosis (MS) and its related disorders, providing the latest research findings and insights to ensure readers are well informed. This book thoroughly examines the underlying genetic factors contributing to the development of the disease while emphasizing the significant role of vitamin D in both the pathogenesis and treatment of MS. Furthermore, this book provides essential information on current treatment guidelines for effectively managing MS during pregnancy. This includes a specific focus on optimizing outcomes and addressing the complexities involved, healthcare professionals are equipped to handle the challenges presented by this specific patient population. Overall, this book delivers meticulous, updated, and extensive information on all aspects of MS, from demographic features and etiopathogenesis to the latest diagnostic and therapeutic interventions. With a focus on delivering valuable knowledge and practical insights, Clinical Aspects of Multiple Sclerosis Essentials and Current Updates serves as an essential resource for healthcare professionals and researchers seeking a deeper understanding of MS.

Key features

  • Explores the practical applications of optical coherence tomography (OCT) and OCT angiography (OCTA) in assessing MS.
  • Delves into utilizing advanced imaging modalities and corresponding radiological findings for the diagnosis and monitoring.
  • Includes cutting-edge technologies: 7 Tesla (7T) magnetic resonance imaging (MRI), diffusion tensor imaging (DTI), positron emission tomography (PET), and magnetic resonance spectroscopy (MR spectroscopy).

Readership

General Neurologists, Neuroimmunologist, Rheumatologist, Emergency Medicine Physicians, Neuro critical Physician, Physician assistants, Nurse practitioner Interventional Neurologists, Intensivists, Patients with MS, Researchers, Medical Students, Pharmacologists Medical school mentor, instructor, teachers, medial lab scientific researcher, neurosurgeons, pediatric physician and resident, OBG-GYN

Table of contents

  1. Introduction of multiple sclerosis and its subtypes, including the new terms clinically isolated syndrome and radiologically isolated syndrome, and diagnostic criteria including McDonald 2017 updates
  2. Introduction to neuromyelitis optica spectrum disorders
  3. Multiple sclerosis epidemiology, epigenetics, and causative factors
  4. Nonmultiple sclerosis demyelinating disorders and common mimickers and masquerading of multiple sclerosis
  5. Current and emerging therapies in multiple sclerosis and practice guidelines
  6. Pediatric multiple sclerosis and current guidelines on DMT therapy in pediatric MS
  7. Prepregnancy, pregnancy, and postpregnancy planning in patients with multiple sclerosis
  8. Rare variant of multiple sclerosis
  9. Imaging of multiple sclerosis, related disorders, and emerging concepts
  10. Application of optical coherence tomography and angiography in multiple sclerosis
  11. Cognitive impairment in multiple sclerosis

Review quotes

"...[a] comprehensive guide covers recent advances in multiple sclerosis (MS), neuromyelitis optica spectrum disorders, and conditions that can mimic MS like Behcet’s disease, Susac syndrome, adult-onset leukodystrophies, sarcoidosis, and Sjogren’s syndrome. [P]rovide insights into research and clinical developments for neuroscientists, neurologists, and students in training who want to learn more about MS [which] includes management of special pediatric and pregnant populations and differentiation of MS from related neuro-immunologic conditions that often mimic it....[Has] a helpful table of contents that provides a nice outline of the topics....Each chapter starts with a helpful list of abbreviations, subheadings, figures, and tables, and ends with a comprehensive list of references. [W]ell-written and offers a useful introduction to MS, encompassing both pathogenesis and diagnostic criteria. It does a great job of reviewing several key topics related to complex diseases like MS, and the many advances that have developed over the past few decades. [P]rovides clinicians with a helpful framework to help with understanding, diagnosis, and treating patients with this disease. For researchers, it highlights many areas where additional research is needed and it describes tools, such as optical coherence tomography (OCT) and OCT angiography, that can be useful in this pursuit. [W]ell-organized and its inclusion of related disorders, which can frequently mimic MS, will help readers distinguish and differentiate. The extensive list of references at the end of each chapter helps provide directions for further study. Lastly, readers are left with inspiration to develop their own insights on these complex diseases that affect so many patients worldwide."—©Doody’s Review Service, 2024, Nara Michaelson, MD (Massachusetts General Hospital)

Product details

  • Edition: 1
  • Latest edition
  • Published: January 16, 2024
  • Language: English

About the editors

SS

Shitiz Sriwastava

Dr. Shitiz K. Sriwastava, MD, is an Assistant Professor in the Department of Neurology with the Division of Multiple Sclerosis and Neuroimmunology at the University of Texas Health Science Center – Houston (UTHealth). He is a board-certified neurologist specialized in multiple sclerosis (MS). During his fellowship training and residency at Wayne State, he performed clinical research on MS and related autoimmune disorders of the central nervous system. He has had many years of experience in MS related clinical trials as a fellow or co-investigator. Dr. Sriwastava has a keen interest in identifying prognostic markers to predict the initiation and progression of MS especially early neurogenerative changes and also DTI studies in MS. He is currently a member of the American Academy of Neurology. His clinical, basic and translational studies in neuroimmunologic diseases have resulted in 50 peer reviewed papers and reports, published abstracts from national and international meetings.

Affiliations and expertise
Assistant Professor, Department of Neurology with the Division of Multiple Sclerosis and Neuroimmunology, The University of Texas Health Science Center at Houston, USA

EB

Evanthia Bernitsas

Evanthia Triantafylou-Bernitsas, MD, joined the Department of Neurology at Wayne State University in 2011. She has completed a neurology residency at Case Western Reserve University and Neuroimmunology Fellowships at the University of Michigan and Baylor College of Medicine. She is the Director of the Multiple Sclerosis Center at Wayne State School of Medicine and Professor of Neurology. Her clinical research focuses on aggressive forms of MS, new immunomodulatory therapies and symptomatic interventions. Dr. Bernitsas directs a very active clinical research program and she is the principal investigator on numerous clinical and investigator-initiated trials. Currently, she serves as the Editor-in Chief in the Neuroimaging section of the Brain Sciences journal. She has published extensively and served in several committees and advisory boards.

Affiliations and expertise
Department of Neurology, Wayne State University, USA

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