Skip to main content

Comparative Mammalian Immunology

The Evolution and Diversity of the Immune Systems of Mammals

  • 1st Edition - February 9, 2023
  • Latest edition
  • Author: Ian R. Tizard
  • Language: English

Comparative Mammalian Immunology: The Evolution and Diversity of the Immune Systems of Mammals provides a review on the current knowledge of mammalian immune systems from a compara… Read more

World Book Day celebration

Where learning shapes lives

Up to 25% off trusted resources that support research, study, and discovery.

Description

Comparative Mammalian Immunology: The Evolution and Diversity of the Immune Systems of Mammals provides a review on the current knowledge of mammalian immune systems from a comparative viewpoint. This reference encompasses recent work on the immune systems of marine mammals, bats and marsupials in addition to other lesser-known species, with the immune systems of humans and laboratory mice as components of chapters on primates and rodents respectively. The book also makes use of the most recent studies on the genomic sequences of the mammals to identify both common and unique features of each mammal's immune system.

The book elucidates the complex, but coordinated and controlled series of interactions involving cells and molecules that has evolved to protect the host against disease. Mammals consist of a highly diverse group of animals in which the immune system has been subjected to a variety of selective pressures. This is reflected in differences in the organization and function of their immune systems, and is especially seen in those gene families characterized by complexity and polymorphism.

Key features

  • Demonstrates multiple diverse pathways and mechanisms to optimize resistance and survival in the face of infectious diseases
  • Shows the clear patterns of emergence of different immunologic traits among the diverse orders of mammals
  • Reflects issues with innate or adaptive immune systems
  • Serves as a comprehensive review of the current state of knowledge of the immune system of each mammalian order

Readership

Immunologists, Comparative Biologists, Evolutionary Scientists, Mammologists, Geneticists Possibly some Veterinarians and interested laypersons Advanced

Table of contents

SECTION 1: MAMMALIAN IMMUNOLOGY

1. The phylogeny of the mammals

2. The evolution of viviparity

3. The evolution of lactation

4. Endothermy

5. The mammalian microbiota and its role in the evolution of the immune system

6. Innate immunity in mammals

7. The evolution of the major histocompatibility complex and kir receptors

8. The generation of b cell and t cell antigen diversity

9. Mammalian lymphoid systems

10. Mammalian longevity and aging

SECTION 2: MAMMALIAN ORDERS

11. Monotremes: Echidnas and platypus

12. Marsupials: Koalas and kangaroos

13. Placentals: Cetartiodactyla: camels and llamas

14. Cetartiodactyla: Pigs and peccaries

15. Ruminants: Cattle, and sheep

16. Cetaceans: Dolphins and whales

17. Chiropterans: Bats

18. Carnivora

19. Perissodactyls: Horses

20. Lagomorphs: Rabbits

21. Rodents: Rats and mice

22. Primates: Monkeys, apes, and humans

23. Paenungulates: Elephants and sirenians

24. Xenarthrans: Sloths and anteaters

25. Synthesis

Product details

  • Edition: 1
  • Latest edition
  • Published: February 24, 2023
  • Language: English

About the author

IT

Ian R. Tizard

Ian R. Tizard, BVMS, BSc, PhD, DSc (Hons), DACVM, is a Diplomate of the American College of Veterinary Microbiologists and a University Distinguished Professor Emeritus of Immunology, Department of Veterinary Pathobiology, The Texas Veterinary Medical Center at Texas A &M University (TAMU), College Station, Texas, USA. Dr. Tizard earned his Bachelor of Veterinary Medicine and Surgery from the University of Edinburgh, Scotland, in 1965. He then completed a Bachelor of Science in Pathology and a PhD in Immunology. After completing his studies, Dr. Tizard became a Post-Doctoral Fellow at the University of Guelph, where he remained as a professor until 1982 when he moved to TAMU. Dr. Tizard wrote the first standardized textbook on Veterinary Immunology in 1977. This text, now in its 11th edition, is used worldwide, and has played a major role in establishing Immunology among the key disciplines.

Affiliations and expertise
University Distinguished Professor of Immunology Emeritus, Department of Veterinary Pathobiology, Texas A&M University, College Station, Texas, USA

View book on ScienceDirect

Read Comparative Mammalian Immunology on ScienceDirect