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Current Developments in Biotechnology and Bioengineering

Functional Genomics and Metabolic Engineering

  • 1st Edition - September 15, 2016
  • Latest edition
  • Editors: P. Gunasekaran, Santosh Noronha, Ashok Pandey
  • Language: English

Current Developments in Biotechnology and Bioengineering: Functional Genomics and Metabolic Engineering provides extensive coverage of new developments, state-of-the-art technolog… Read more

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Description

Current Developments in Biotechnology and Bioengineering: Functional Genomics and Metabolic Engineering provides extensive coverage of new developments, state-of-the-art technologies, and potential future trends in the field, compiling the latest ideas from across the entire arena of biotechnology and bioengineering.

This volume provides data-based scientific knowledge and state-of-art information on functional genomics and metabolic engineering. It covers the core subjects of functional genomics, such as epigenomics, metagenomics, genomics of extremophiles, genomics studies in nutrient transport, genomics of miRNA, and genomics of pathogenesis.

An overview of metabolic engineering theories and approaches is supported with specific important examples of secondary metabolites, including Streptomyces, pentose utilization in E. coli, bacterial ethanol fermentation, yeast mediated benzaldehyde biotransformation, carotenoid production, acetic acid production by E. coli, and NADH regeneration.

Key features

  • Provides state-of-the-art information and applications of functional genomics and metabolic engineering as applied to biotechnology
  • Supports the education and understanding of biotechnology education and R&D
  • Demonstrates new means of enabling cells to produce valuable proteins, polypeptides, and primary and secondary metabolites

Readership

Postgraduate and PhD students and researchers in academia, government and corporate research in the area of bioengineering/biochemical engineering, biomedical/biological engineering and industrial biotechnology

Table of contents

Section 1: Functional Genomics1. Functional epigenomics 2. Functional Metagenomics3. Functional genomics of extremophiles4. Functional genomics studies in nutrient transport5. Functional genomics of miRNA6. Functional genomics of pathogenesis

Section 2: Metabolic Engineering7. Overview of metabolic engineering theories and approaches8. Polyketide synthesis 9. Secondary metabolites from Streptomyces 10. Pentose utilization in E. coli 11. Bacterial ethanol fermentation 12. Yeast mediated benzaldehyde biotransformation 13. Carotenoid production14. Acetic acid production by E. coli 15. NADH regeneration

Product details

  • Edition: 1
  • Latest edition
  • Published: September 16, 2016
  • Language: English

About the editors

PG

P. Gunasekaran

Prof. P. Gunasekaran is a Senior Professor of Microbiology in India. He has 33 years of teaching and research experience in Microbiology, Biotechnology and Genomics. He obtained his Bachelor’s Degree in Chemistry (1974) and Master’s Degree in Biology (1976) from Madurai Kamaraj University, Madurai. Subsequently, he obtained his Doctorate Degree in Microbiology (1980) from Haryana Agricultural University, Hisar. He started his career as a Lecturer cum Curator in Microbiology at Punjab University, Chandigarh in 1980 and became a Faculty of Madurai Kamaraj University in 1981. Presently, he is serving as the Vice-Chancellor of Thiruvalluvar University, Vellore.

Prof. P. Gunasekaran has made significant contributions in Industrial Microbiology especially on ethanol fermentation technology and microbial enzyme technology. His research has been focused mainly on Zymomonas mobilis, an ethanol producing bacterium. In addition to the research on Z. mobilis, he has made significant contributions in process optimization and production of various industrial enzymes from different bacterial and fungal sources. He visited several countries worldwide including USA, UK, France, Mexico, Japan, South Korea and Hungary to conduct colloborative research programs.

He has introduced a new postgraduate course, M.Sc. Genomics at MKU, for the first time in India, Under the UGC-supported Centre for Excellence in Genomic Sciences (CEGS) programme. He elevated this course to a new hight as Integrated M.Sc.–Ph.D. course in Genomics, for the first time in India with the support of DBT-supported Interdisciplinary Programme of Life Sciences (IPLS). With the support from the UGC, New Delhi he has established Networking Research Centre in Biological Sciences (NRCBS) with State of the Art research laboratory facility which cater the need of the researchers from any time from any where in the country.

He has guided 36 Ph.D students in his career and 4 students are waiting for final viva voce examination. He is presently guiding 8 Ph.D students at MKU. He has published 150 Research articles in National and International Journals with a cumulative imapct foctor of 250 and his reserach articles has been cited 1923 time in various journal artilces with a h-index of 23 and i10 index of 50. In addition, he has contributed 28 book chapters in books published by leading publishers such as Springer. He has presented his research findings in more than 200 National and International conferences. He is serving as the Editor of three International journals such as Applied Biotechnology and Biotechnology (USA), Journal of Microbiology and Biotechnology (South Korea) and Indian Journal of Microbiology (India). In addition, he served as the Guest Editor of special issues in leading Indian journals such as Current Science, Journal of Scientific Research, Indian Journal of Biotechnology and Indian Journal of Experimental Biology.

At national level, he has been elected as the President of Biotechnology Research Society of India (BRSI), India, twice consecutively (2011- 13 and 2013-16). He served as the President of Association of Microbiologists of India (AMI), India for the year 2008-2009. During his tenure, the AMI had tie-up with international societies such as American Society for Microbiology (ASM) and International Society for Microbial Ecology (ISME). The official journal of the AMI, Indian Journal of Microbiology has been published published by Springer. He has chaired and served as a member of several Committee, Councils and Boards of various fundsing agencies. He has organized two International Conferences and more than 25 workshops /summer schools/ winter schools.

Affiliations and expertise
Vice-Chancellor, Thiruvalluvar University, Vellore, India

SN

Santosh Noronha

Dr Santosh Noronha is a biochemical engineer by training who has evolved multidisciplinary interests. He has focused on understanding various metabolic and regulatory aspects of microbial systems, towards rationally manipulating their productivity for production of therapeutics. He is Assistant Professor in the Department of Chemical Engineering, Indian Institute of technology, Mumbai, India.
Affiliations and expertise
Assistant Professor in the Department of Chemical Engineering, Indian Institute of technology, Mumbai, India

AP

Ashok Pandey

Prof. Ashok Pandey is currently Executive Director, Centre for Energy and Environmental Sustainability-India, Lucknow. His major research and technological development interests are industrial and environmental biotechnology and energy biosciences, focusing on biomass to biofuels and chemicals, waste to wealth and energy, etc.

Affiliations and expertise
Executive Director, Centre for Energy and Environmental Sustainability-India, Lucknow, India

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