Current Topics in Bioenergetics

Contributors

Preface

Contents of Previous Volumes

Structure of Cytochrome Oxidase Redox Centers in Native and Modified Forms: An EXAFS Study

I. Introduction

II. General Background

III. EXAFS Studies on the Resting Enzyme

IV. Cu EXAFS

V. Fe EXAFS

VI. EXAFS Study on the Pulsed Oxidase

VII. Chemical Studies

VIII. The Active Site of Cytochrome Oxidase in Its Resting (S-Bridged) and Pulsed (Nonbridged) Forms

IX. Summary

References

X-Ray and Neutron Diffraction for Probing the Interactions of Small Molecules with Membrane Structures

I. Overview

II. Small Molecule-Membrane Systems Employed

III. Neutron Diffraction Approach

IV. X-Ray Diffraction Approach

V. Drug "Conformation" and Orientation in Biological Membranes

VI. Molecular Model for Drug Binding to Cardiac Sarcolemmal Receptors

VII. Conclusions

References


19F NMR Investigations of Membranes

I. Introduction

II. Types of Nuclei Used in Membrane Studies by NMR

III. Theoretical Aspects of 19F NMR as Applied to Membrane Systems

IV. 19F NMR Studies of Model Membrane Systems

V. 19F NMR Studies of Bacterial Membrane Lipids

VI. A Strategy For Investigating Protein-Lipid Interactions in Membranes Using 19F NMR

VII. Perturbations Produced by Substituting 19F Atoms for 1H Atoms in Membrane Lipids and Proteins

VIII. Summary

References

Metal Ion NMR: Application to Biological Systems

I. Introduction

II. Theory

III. Applications

References

Circular Dichroism Studies of Electron-Transport Components

I. Introduction

II. Methodology

III. Intrinsic Circular Dichroism Spectra

IV. Extrinsic Circular Dichroism Spectra

References

Index