Skip to main content
Elsevier
View Cart

Current Topics in iPSCs Technology

  • 1st Edition, Volume 17 - January 18, 2022
  • Latest edition
  • Editor: Alexander Birbrair
  • Language: English

Current Topics in iPSCs provides a deep analysis of the underlying fundamentals that support short and mid-term developments and milestones in the business of mesenchymal stem cell… Read more

World Book Day celebration

Where learning shapes lives

Up to 25% off trusted resources that support research, study, and discovery.

Explore resources

Description

Current Topics in iPSCs provides a deep analysis of the underlying fundamentals that support short and mid-term developments and milestones in the business of mesenchymal stem cell therapies. This volume explores the next frontier of MSC therapies and how the transformational potential of therapeutic adult cells will be realised in all therapy areas. The impacts of clinical and economic benefits are dissected throughout each of the chapters. Written by thought leaders in the field for those curious about the interface of science and business.

Key features

  • Explores the strategy at the forefront of the science of mesenchymal stem cells
  • Provides an overview of all therapy areas where MSC and MSC-derived products can be used therapeutically
  • Depicts transformational changes in healthcare that enable the implementation of MSC-powered technology platforms

Readership

Researchers and scientists in stem cell therapy, cell biology, regenerative medicine, and organ transplantation; Graduate and undergraduate students in the above fields

Table of contents

1. Regulatory and Policy Considerations in iPSC Research

2. HiPSCs for Population Genetics

3. Using Human Induced Pluripotent Stem Cells to Advance Personalized/Precision Medicine

4. hiPSC disease modeling with 3D organoids: Bioengineering perspective

5. The Differentiation of Embryonic Stem Cells and Induced Pluripotent Stem Cells into Airway and Alveolar Epithelial Cells

6. Transplantation of iPSC-derived human kidney organoids

7. An update on clinical applications of iPSCs from a genomic point of view

8. DNA Damage and Replication in Induced Pluripotent Stem Cells

9. Epigenetic modifications in induced pluripotent stem cells to boost myogenic commitment

10. Applications for Induced Pluripotent Stem Cells (iPSC) in Reproductive Medicine

11. iPSCs in Insulin Resistance, Type 2 Diabetes and the Metabolic Syndrome

12. Induced pluripotent stem cells for cystic fibrosis

13. Exploring 15q13.3 Copy Number Variants in iPSCs

14. Human induced pluripotent stem cells for modeling Brugada syndrome

15. iPSCs for Erythromycin Arrhythmogenicity Testing

16. Therapeutic Potential of Induced Pluripotent Stem Cell derived Extracellular Vesicles: Quo Vadis? Terra Incognito

17. Proteomic Approach for Creation of the Protein Marker Panels to Control for Quality of Human Induced Pluripotent Stem Cells (hiPSCs)

18. Application of induced pluripotent stem cells in tissue engineering

19. Application of iPSC-derived secretome in regenerative medicine

20. iPSCs and toxicology: predictive tool for present and future

21. Rejuvenation through iPSCs and reprogramming in vivo and in vitro

Product details

  • Edition: 1
  • Latest edition
  • Volume: 17
  • Published: January 18, 2022
  • Language: English

About the editor

AB

Alexander Birbrair

Dr. Alexander Birbrair received his bachelor’s biomedical degree from Santa Cruz State University in Brazil. He completed his PhD in Neuroscience, in the field of stem cell biology, at the Wake Forest School of Medicine under the mentorship of Osvaldo Delbono. Then, he joined as a postdoc in stem cell biology at Paul Frenette’s laboratory at Albert Einstein School of Medicine in New York. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. His research is funded by the Serrapilheira Institute, CNPq, CAPES, and FAPEMIG. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC), and, in 2019, he was elected member of the Global Young Academy (GYA), and in 2021, he was elected affiliate member of The World Academy of Sciences (TWAS). He is the Founding Editor and Editor-in-Chief of Current Tissue Microenvironment Reports, and Associate Editor of Molecular Biotechnology. Alexander also serves in the editorial board of several other international journals: Stem Cell Reviews and Reports, Stem Cell Research, Stem Cells and Development, and Histology and Histopathology.
Affiliations and expertise
Department of Pathology, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil Department of Radiology, Columbia University Medical Center, Medical Center, USA

View book on ScienceDirect

Read Current Topics in iPSCs Technology on ScienceDirect