Skip to main content
Elsevier

Degenerative Cervical Myelopathy

From Basic Science to Clinical Practice

  • 1st Edition - November 23, 2023
  • Latest edition
  • Editor: Michael G. Fehlings
  • Language: English

Degenerative Cervical Myelopathy: From Basic Science to Clinical Practice lays the foundation for understanding DCM manifestation, pathophysiology, diagnosis and treatment… Read more

Data Mining & ML

Unlock the cutting edge

Up to 20% on trusted resources. Build expertise with data mining, ML methods.

Explore now

Description

Degenerative Cervical Myelopathy: From Basic Science to Clinical Practice lays the foundation for understanding DCM manifestation, pathophysiology, diagnosis and treatment strategies. The book covers the latest basic and clinical research, updates on patient management strategies, and discusses promising neuroprotective therapies for the future of DCM care. Written by international experts across a range of topics related to degenerative cervical myelopathy, the book helps readers understand the challenges and future directions of patient management.

As degenerative cervical myelopathy (DCM) is the leading cause of spinal cord dysfunction and one of the most common indications for spinal surgery worldwide, the term DCM encompasses a group of chronic, non-traumatic spinal cord injuries that occur due to degenerative changes in the cervical spine (e.g. disc spondylosis or repetitive dynamic injury from hyper-mobility).

Key features

  • Covers recent clinical trial advancements and the impact of trial findings
  • Presents recent clinical guidelines for the management of degenerative cervical myelopathy, providing readers with insights regarding the translation of research from bench to bedside
  • Provides readers with the skills needed to understand the translational pathway using real-life examples

Readership

Orthopaedic Surgeons, Neurosurgeons, Clinical Spine Fellows, Residents, Clinical and Basic Researchers, Public Health Organizations, Ergonomists, Medical Students, Rehabilitation Specialists, Neurologists, Physiatrists, Physiotherapists, Chiropractors, Family Physicians, General Internists, reference for anyone interested in better understanding degenerative changes to the cervical spine, undergraduate and graduate level neuroscience, molecular biology, anatomy, genetics, and motor behavior students with an interest in nervous system injury, members of industry and policy makers who are looking to better understand degenerative cervical myelopathy management practices

Table of contents

1. Overview of DCM

2. Anatomy and Physiology of Cervical Spine and Cervical Spinal Cord

3. Epidemiology, Genetics and Classification of DCM

4. Pathophysiology of DCM

5. Clinical Assessment Tools

6. Imaging of DCM

7. Electrophysiological Assessment of DCM

8. Assessment of Cervical Alignment and Deformity

9. Patient Trajectory and Natural History

10. Role of the Primary Care Practitioner in the Assessment and Management of DCM

11. RECODE Priorities

12. Overview of Management Options for DCM (reference current guidelines)

13. Prehabilitation and Rehabilitation for DCM

14. Decision Making in Surgical Management of DCM

15. Anterior Surgical Approaches to Treat DCM

16. Posterior Surgical Approaches to Treat DCM – Cervical Laminectomy

17. Posterior Surgical Approaches to Treat DCM – Cervical Laminoplasty

18. Serological, Genetic and Imaging Biomarkers

19. Nonoperative Management of DCM (including potential neuroprotective strategies)

20. Neuroregenerative Strategies for DCM

21. State of the Art and Future Directions of DCM

Review quotes

"...provides an overview of the relevant anatomy and physiology of cervical spine disease and how to appropriately apply this knowledge clinically. The detailed table of contents is well organized and allows easy navigation to topics of interest. [It] serves as a useful resource for spine surgeons in both training and practice to review foundational knowledge necessary for the diagnosis and work-up of degenerative cervical disease, surgical approaches and techniques, non-operative management, and for primary care providers in treatment of these patients.... Overall, this book is easy to navigate with the detailed table of contents,... remains comprehensive with strong references. I recommend this textbook to senior spine surgeons who are currently in training or in practice and have an interest in research." Review by Sophia Peng, MD (University of Illinois at Chicago College of Medicine), ©Doody's Review Service, 2025.

Product details

  • Edition: 1
  • Latest edition
  • Published: November 23, 2023
  • Language: English

About the editor

MF

Michael G. Fehlings

Dr. Fehlings is the Vice Chair Research for the Department of Surgery at the University of Toronto and Head of the Spinal Program at Toronto Western Hospital, University Health Network. Dr. Fehlings is a Professor of Neurosurgery at the University of Toronto, holds the Gerry and Tootsie Halbert Chair in Neural Repair and Regeneration, is a Scientist at the McEwen Centre for Regenerative Medicine and a McLaughlin Scholar in Molecular Medicine. In the fall of 2008, Dr. Fehlings was appointed the inaugural Director of the University of Toronto Neuroscience Program (which he held until June 2012) and is currently Co-Director of the University of Toronto Spine Program. Dr. Fehlings combines an active clinical practice in complex spinal surgery with a translationally oriented research program focused on discovering novel treatments to improve functional outcomes following spinal cord injury (SCI).
Affiliations and expertise
Professor, Vice Chair Research, Department of Surgery, Halbert Chair in Neural Repair and Regeneration, Co-Chairman Spinal Program, University of Toronto; Head Spinal Program, McEwen Centre for Regenerative Medicine, Toronto Western Hospital

View book on ScienceDirect

Read Degenerative Cervical Myelopathy on ScienceDirect