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Diagnostic Pathology: Cardiovascular

  • 3rd Edition - February 14, 2023
  • Latest edition
  • Authors: Dylan V. Miller, Monica P. Revelo
  • Language: English

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all aspects of ca… Read more

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Description

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all aspects of cardiovascular pathology, including new cardiac devices, molecular panels and genetics, the latest tumor classifications, up-to-date COVID-19 information, and imaging, this volume incorporates the most recent scientific and technical knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Cardiovascular is a visually stunning, one-stop resource for every practicing pathologist, resident, student, or fellow as an ideal day-to-day reference or as a reliable training resource.

Key features

  • Covers all areas of cardiovascular pathology, organizing chapters by how specimens are most often encountered in practice—biopsy, explant and surgical specimens, and autopsy—as well as by anatomic site
  • Contains significantly updated information throughout (text, images, illustrations, and references) including the latest World Health Organization and International Collaboration on Cancer Reporting tumor classifications, as well as new details related to staging and grading of tumors of the heart, and COVID-19 information
  • Evaluates a new generation of cardiac devices in surgical and autopsy specimens in both images and text
  • Includes new material on genetics and sudden cardiac death and cardiomyopathy, and recent recommended amyloid treatment therapies
  • Features nearly 1,500 images, including carefully annotated histology and gross pathology photographs, vivid medical illustrations, photomicrographs, and electron micrographs to help practicing and in-training pathologists reach a confident diagnosis
  • Employs consistently templated chapters, bulleted content, key facts, a variety of tables, annotated images, pertinent references, and an extensive index for quick, expert reference at the point of care
  • Includes an eBook version that enables you to access all text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud

Readership

Anatomic and clinical pathologists in practice, as well as pathologists at all levels of training

Table of contents

SECTION 1: HEART, ENDOMYOCARDIAL BIOPSY
CONGENITAL/GENETIC

4 Endocardial Fibroelastosis Syndrome
Monica P. Revelo, MD, PhD

6 Arrhythmogenic Cardiomyopathy
Dylan V. Miller, MD, Jagdish Butany, MBBS, MS, FRCPC, and Monica P. Revelo, MD, PhD

12 Fatty Acid Metabolic Disorders
Monica P. Revelo, MD, PhD

14 Mitochondrial Myopathies
Monica P. Revelo, MD, PhD

18 Muscular Dystrophies
Monica P. Revelo, MD, PhD

22 Glycogen Storage Diseases
Monica P. Revelo, MD, PhD

24 Fabry Disease, Heart
Monica P. Revelo, MD, PhD

28 LAMP2 Mutation (Danon Disease)
Jagdish Butany, MBBS, MS, FRCPC, Amar Ibrahim, MB, ChB, MSc, and Monica P. Revelo, MD, PhD

ACQUIRED

30 Amyloid Deposition, Heart
Elizabeth H. Hammond, MD and Monica P. Revelo, MD, PhD

38 Hemochromatosis, Heart
Philippe Romeo, MD and Monica P. Revelo, MD, PhD

40 Anthracycline Cardiotoxicity
Brandon T. Larsen, MD, PhD and Monica P. Revelo, MD, PhD

42 Catecholamine Cardiomyopathy
Monica P. Revelo, MD, PhD

44 Cocaine Cardiotoxicity
Dylan V. Miller, MD and Brian J. Hall, MD

46 Immune Checkpoint Inhibitor Toxicity
Monica P. Revelo, MD, PhD and Dylan V. Miller, MD

INFLAMMATORY

50 Lymphocytic Myocarditis
Monica P. Revelo, MD, PhD

54 Giant Cell Myocarditis
Brandon T. Larsen, MD, PhD and Monica P. Revelo, MD, PhD

56 Eosinophilic (Löffler) Myocarditis
Monica P. Revelo, MD, PhD

60 Sarcoidosis, Heart
Monica P. Revelo, MD, PhD

62 Acute Rheumatic Carditis
Monica P. Revelo, MD, PhD

66 Eosinophilic Granulomatosis With Polyangiitis
Monica P. Revelo, MD, PhD

68 Viral Myocarditis
Dylan V. Miller, MD, Brian J. Hall, MD, and Nikhil Sangle, MD, FRCPath

70 Toxoplasmosis, Heart
Monica P. Revelo, MD, PhD

72 Chagas Disease, Heart
Dylan V. Miller, MD and Brian J. Hall, MD

76 Lyme Disease and Rickettsial Myocarditis
Dylan V. Miller, MD and Brian J. Hall, MD

80 SARS-CoV-2 (COVID-19)-Related Cardiovascular Disease
Dylan V. Miller, MD and Monica P. Revelo, MD, PhD

84 Lupus Erythematosus, Heart
Monica P. Revelo, MD, PhD

TRANSPLANT REJECTION

90 Acute Cellular Transplant Rejection, Heart
Elizabeth H. Hammond, MD and Monica P. Revelo, MD, PhD

96 Antibody-Mediated Transplant Rejection, Heart
Elizabeth H. Hammond, MD and Monica P. Revelo, MD, PhD

102 Quilty Lesions
Billie Fyfe, MD and Monica P. Revelo, MD, PhD

106 Previous Biopsy Sites, Heart Transplant
Billie Fyfe, MD and Monica P. Revelo, MD, PhD

108 Posttransplant Lymphoproliferative Disorder, Heart
Dylan V. Miller, MD, Brian J. Hall, MD, and Nikhil Sangle, MD, FRCPath

110 Harvesting Injury/Acute Ischemia, Heart
Billie Fyfe, MD and Monica P. Revelo, MD, PhD

SECTION 2: HEART, RESECTION
HEART EXPLANT

116 Hypertrophic Cardiomyopathy
Vidhya Nair, MBBS, MD, FRCPC and Monica P. Revelo, MD, PhD

122 Idiopathic Dilated Cardiomyopathy
Dylan V. Miller, MD

126 Ischemic Heart Disease
Vidhya Nair, MBBS, MD, FRCPC and Monica P. Revelo, MD, PhD

130 Overview of Coronary Artery Stents
Dylan V. Miller, MD

134 Cardiac Allograft Vasculopathy
Monica P. Revelo, MD, PhD

140 Radiation Injury, Heart
Dylan V. Miller, MD and Philippe Romeo, MD

142 Cardiac Conduction System Disease
Dylan V. Miller, MD

150 Ventricular Assist Devices
Dylan V. Miller, MD

156 Approach to Cardiomyopathy (Worksheet)
Dylan V. Miller, MD

158 Approach to Cardiomyopathy Diagnosis
Dylan V. Miller, MD

SECTION 3: HEART, TUMORS
BENIGN

166 Cardiac Myxoma
Dylan V. Miller, MD and Joseph J. Maleszewski, MD

172 Papillary Fibroelastoma
Dylan V. Miller, MD and Joseph J. Maleszewski, MD

176 Cardiac Rhabdomyoma
Dylan V. Miller, MD and Joseph J. Maleszewski, MD

180 Cardiac Fibroma
Dylan V. Miller, MD and Joseph J. Maleszewski, MD

184 Ectopic Tissues, Heart
Dylan V. Miller, MD and Joseph J. Maleszewski, MD

186 Lipomatous Hypertrophy of Atrial Septum
Dylan V. Miller, MD and Billie Fyfe, MD

MALIGNANT

188 Cardiac Lymphoma
Dylan V. Miller, MD, Brian J. Hall, MD, and Nikhil Sangle, MD, FRCPath

190 Cardiac Angiosarcoma
Joseph J. Maleszewski, MD and Monica P. Revelo, MD, PhD

194 Cardiac Sarcoma, Other
Dylan V. Miller, MD and Joseph J. Maleszewski, MD

198 Cardiac Metastases
Dylan V. Miller, MD and Jagdish Butany, MBBS, MS, FRCPC

SECTION 4: CARDIAC VALVES, NATIVE
AORTIC

206 Unicommissural Aortic Valve
Dylan V. Miller, MD and Jagdish Butany, MBBS, MS, FRCPC

210 Bicuspid Aortic Valve
Jagdish Butany, MBBS, MS, FRCPC, Amar Ibrahim, MB, ChB, MSc, and Monica P. Revelo, MD, PhD

214 Senile Calcific Aortic Stenosis
Monica P. Revelo, MD, PhD

218 Discrete Membranous Subaortic Stenosis
Dylan V. Miller, MD

MITRAL


220 Myxomatous Mitral Valve Disease
Dylan V. Miller, MD and Philippe Romeo, MD

224 Rheumatic Heart Disease
Dylan V. Miller, MD and Philippe Romeo, MD

TRICUSPID

228 Carcinoid Heart Disease
Joseph J. Maleszewski, MD and Monica P. Revelo, MD, PhD

232 Ebstein Anomaly
Dylan V. Miller, MD and Philippe Romeo, MD

PULMONARY

234 Congenital Pulmonary Stenosis
Dylan V. Miller, MD and Brian J. Hall, MD

ENDOCARDITIS

236 Endocarditis, Native Valve
Vidhya Nair, MBBS, MD, FRCPC and Monica P. Revelo, MD, PhD

240 Nonbacterial Thrombotic Endocarditis
Vidhya Nair, MBBS, MD, FRCPC and Monica P. Revelo, MD, PhD

SECTION 5: CARDIAC VALVES
PROSTHETIC

246 Leaflet Degeneration, Prosthetic Valves
Jagdish Butany, MBBS, MS, FRCPC and Monica P. Revelo, MD, PhD

250 Thrombosis of Prosthetic Valves
Dylan V. Miller, MD, Jagdish Butany, MBBS, MS, FRCPC, and Amar Ibrahim, MB, ChB, MSc

252 Endocarditis, Prosthetic Valve
Dylan V. Miller, MD and Jagdish Butany, MBBS, MS, FRCPC

258 Mechanical Heart Valve Prostheses: Modes of Failure
Dylan V. Miller, MD, Jagdish Butany, MBBS, MS, FRCPC, and Amar Ibrahim, MB, ChB, MSc

260 Catheter-Deployed Valve Therapies
Dylan V. Miller, MD and Monica P. Revelo, MD, PhD

SECTION 6: PERICARDIUM
INFLAMMATORY

268 Acute Pericarditis
Monica P. Revelo, MD, PhD

272 Constrictive Pericarditis
Monica P. Revelo, MD, PhD

274 Tuberculous Pericarditis
Monica P. Revelo, MD, PhD

TUMORS

276 Lymphoma, Pericardium
Dylan V. Miller, MD

278 Metastatic Tumor, Pericardium
Billie Fyfe, MD and Monica P. Revelo, MD, PhD

282 Mesothelioma, Pericardium
Dylan V. Miller, MD and Joseph J. Maleszewski, MD

286 Mesothelial/Monocytic Incidental Cardiac Excrescence
Dylan V. Miller, MD

SECTION 7: VASCULAR DISEASE
ENDARTERECTOMY/ATHERECTOMY/THROMBECTOMY

290 Overview of Peripheral Vascular Specimens
Dylan V. Miller, MD and Billie Fyfe, MD

296 Thromboembolus, Vascular
Billie Fyfe, MD and Monica P. Revelo, MD, PhD

THORACIC AORTA


300 Aortic Degenerative Diseases
Dylan V. Miller, MD and Brandon T. Larsen, MD, PhD

308 Genetic Diseases of the Aorta
Joseph J. Maleszewski, MD and Monica P. Revelo, MD, PhD

312 Noninfectious Aortitis
Dylan V. Miller, MD

316 Takayasu Arteritis
Dylan V. Miller, MD

320 Aortic Dissection
Dylan V. Miller, MD and Billie Fyfe, MD

324 Aortic Coarctation
Dylan V. Miller, MD and Monica P. Revelo, MD, PhD

ABDOMINAL AORTA

328 Aortic Atherosclerosis and Complications
Billie Fyfe, MD and Monica P. Revelo, MD, PhD

334 Chronic Periaortitis and IgG4-Related Disease
Dylan V. Miller, MD

336 Mycotic Aneurysm
Monica P. Revelo, MD, PhD

CORONARY ARTERIES

340 Atherosclerosis, Coronary
Monica P. Revelo, MD, PhD

344 Coronary Artery Dissection
Monica P. Revelo, MD, PhD

348 Kawasaki Disease
Vidhya Nair, MBBS, MD, FRCPC and Monica P. Revelo, MD, PhD

352 Coronary Artery Emboli
Monica P. Revelo, MD, PhD

TEMPORAL ARTERIES

354 Giant Cell/Temporal Arteritis
Dylan V. Miller, MD and Monica P. Revelo, MD, PhD

PERIPHERAL VESSELS

358 Buerger Disease (Thromboangiitis Obliterans)
Dylan V. Miller, MD and Jagdish Butany, MBBS, MS, FRCPC

362 Fibromuscular Dysplasia
Dylan V. Miller, MD and A. Brad Farris, III, MD

368 Segmental Arterial Mediolysis
Dylan V. Miller, MD

370 Mönckeberg Medial Calcific Sclerosis
Brandon T. Larsen, MD, PhD and Monica P. Revelo, MD, PhD

372 Behçet Disease
Dylan V. Miller, MD and Brandon T. Larsen, MD, PhD

376 Infectious Vasculitis
Dylan V. Miller, MD and Brandon T. Larsen, MD, PhD

382 Lymphocytic Venulitis
Monica P. Revelo, MD, PhD

384 Varicosities
Dylan V. Miller, MD and Billie Fyfe, MD

386 Hypertensive Renovascular Diseases
Dylan V. Miller, MD, A. Brad Farris, III, MD, and Brandon T. Larsen, MD, PhD

VASCULAR TISSUE GRAFTS


390 Vascular Graft Pseudoaneurysm
Jagdish Butany, MBBS, MS, FRCPC, Pooja Gupta, MBBS, DNB, and Monica P. Revelo, MD, PhD

SECTION 8: VASCULAR TUMORS
BENIGN

396 Hemangioma
Dylan V. Miller, MD and Brandon T. Larsen, MD, PhD

406 Angiomyolipoma
Dylan V. Miller, MD, Satish K. Tickoo, MD, and Victor E. Reuter, MD

410 Glomus Tumor
Dylan V. Miller, MD and Brandon T. Larsen, MD, PhD

418 Cystic Lymphangioma
Monica P. Revelo, MD, PhD

420 Arteriovenous Malformations
Dylan V. Miller, MD

MALIGNANT

424 Epithelioid Hemangioendothelioma
Dylan V. Miller, MD and Brandon T. Larsen, MD, PhD

428 Kaposi Sarcoma
Dylan V. Miller, MD and Brandon T. Larsen, MD, PhD

434 Angiosarcoma
Dylan V. Miller, MD and Brandon T. Larsen, MD, PhD

SECTION 9: AUTOPSY
CARDIAC

442 Coronary Artery Bypass Grafting
Dylan V. Miller, MD

446 Valve Replacement (Including Transcatheter)
Dylan V. Miller, MD and Brandon T. Larsen, MD, PhD

452 Infective Endocarditis
Dylan V. Miller, MD

458 Ventricular Assist Device Insertion
Dylan V. Miller, MD and Brandon T. Larsen, MD, PhD

462 Heart Transplant
Dylan V. Miller, MD

VASCULAR

468 Thoracic Aortic Aneurysm Repair
Dylan V. Miller, MD, Billie Fyfe, MD, and George P. Batsides, MD

474 Abdominal Aortic Aneurysm
Dylan V. Miller, MD and Billie Fyfe, MD

478 Cerebral Aneurysm and Vascular Malformation
Dylan V. Miller, MD and Roy H. Rhodes, MD, PhD

Review quotes

"This book is the cardiovascular volume from the Elsevier Diagnostic Pathology series. The content spans the full range of cardiovascular conditions, from pericardium, to heart, to blood vessels, addressing both neoplastic and non-neoplastic pathologies. The previous edition was published in 2018." -©Doody’s Review Service, 2024, Catherine S Morris, MD (University of Michigan Medical School)

Product details

  • Edition: 3
  • Latest edition
  • Published: February 14, 2023
  • Language: English

About the authors

DM

Dylan V. Miller

Dylan V. Miller is a Professor (Clinical) at the University of Utah School of Medicine's Department of Pathology and is Director of Electron Microscopy and Immunostains at Intermountain Central Laboratory in Salt Lake City, Utah
Affiliations and expertise
Professor (Clinical), Department of Pathology, University of Utah School of Medicine, Director of Electron Microscopy and Immunostains, Intermountain Central Laboratory, Salt Lake City, Utah, USA

MR

Monica P. Revelo

Monica P. Revelo is a Professor at the University of Utah School of Medicine's Department of Pathology, and is Medical Director of Renal and Cardiovascular Pathology at ARUP Laboratories in Salt Lake City, Utah
Affiliations and expertise
Professor, Department of Pathology, University of Utah School of Medicine, Medical Director of Renal and Cardiovascular Pathology, ARUP Laboratories, Salt Lake City, Utah, USA