Essential Guide to Neurodegenerative Disorders
Mechanistic, Diagnostic and Therapeutic Advances
- 1st Edition - November 24, 2024
- Latest edition
- Editor: Wael Mohamed
- Language: English
Handbook of Neurodegenerative Disorders: Mechanism, Diagnostic and Therapeutic Advances provides a comprehensive review on the current biomedical studies aimed at identi… Read more
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Description
Description
Handbook of Neurodegenerative Disorders: Mechanism, Diagnostic and Therapeutic Advances provides a comprehensive review on the current biomedical studies aimed at identifying the underlying causes of neurodegeneration. This book reviews the most recent developments in molecular and cellular processes altered during neurodegeneration. Divided into four parts, the first covers the mechanism of cell death in neurodegeneration. The second section reviews the recent progress in gene and gene products in neurodegeneration, including Huntington's disease, Parkinson's disease, Friedreich' s ataxia, and spinal muscular atrophy. The final sections cover the current and future diagnostic techniques of neurodegenerative disorders along with therapeutic approaches.
Key features
Key features
- Reviews big data and neurodegeneration disorders, including gene mapping
- Examines the structural basis of protein assembly into amyloid filaments in neurodegenerative disease
- Covers the progress and challenges of pharmacotherapy of neurodegenerative disorders
Readership
Readership
Student, Researchers and Clinician in Neuroscience, Neurology and Movement disorders
Table of contents
Table of contents
Part-I: Mechanism of cell death in neurodegeneration
1. Pathways in AD
2. Shared signalling pathways in Alzheimer’s and metabolic disease
3. Abeta pathology in AD and its potential to seed and propagate
4. Single-cell approaches to identify shared and distinct signatures across neurodegenerative diseases
5. Modelling of neurodegenerative disease using brain organoids
6. The structural basis of protein assembly into amyloid filaments in neurodegenerative disease-Benjamin
7. Blood brain barrier in neurodegenerative disorders
8. Protein misfolding in neurodegeneration
9. Neuroinflammation and neurodegeneration
10. Gut-Brain Axis in neurodegeneration
11. Modelling Neural Circuits in Parkinson’s Disease
12. Neuropathology of Parkinsonism in Alzheimer’s Disease
13. Huntington Disease updates
14. Neuroinflammation in neurodegeneration
Part-II: Gene and gene products in neurodegeneration
15. Big data and neurodegeneration disorders
16. Genomics and PD
17. RNA Binding Proteins and the Genesis of Neurodegenerative Diseases-Ahmed Moustafa, Egypt
18. Molecular Genetics of Huntington’s Disease
19. neuronopathic LSDs: opportunities and challenges
20. Nutrigenomics and PD
21. Genes and MS: updates
22. Genetic mapping and big data in ALS
Part-III: Present and future diagnostic approaches of neurodegenerative disorders
23. Biomarkers in AD
24. Biomarkers of PD
25. HMGB complex in PD diagnosis
26. Psychological assessment of PD patients
Part-IV: Present and future therapeutics of neurodegenerative disorders
27. Pharmacotherapy of neurodegenerative disorders: challenges and hopes
28. Advanced Drug Delivery Nanosystems: Perspectives and Regulatory Issues
29. Towards the Development of a Device to Improve the Gait of Patients Suffering from Parkinson’s Disease
30. Developing Antisense Therapies for Neurodegenerative Diseases
31. Advances in Gene Therapies for the CNS
32. Nutrition and PD
33. Stem cell therapy in NDG disorders
1. Pathways in AD
2. Shared signalling pathways in Alzheimer’s and metabolic disease
3. Abeta pathology in AD and its potential to seed and propagate
4. Single-cell approaches to identify shared and distinct signatures across neurodegenerative diseases
5. Modelling of neurodegenerative disease using brain organoids
6. The structural basis of protein assembly into amyloid filaments in neurodegenerative disease-Benjamin
7. Blood brain barrier in neurodegenerative disorders
8. Protein misfolding in neurodegeneration
9. Neuroinflammation and neurodegeneration
10. Gut-Brain Axis in neurodegeneration
11. Modelling Neural Circuits in Parkinson’s Disease
12. Neuropathology of Parkinsonism in Alzheimer’s Disease
13. Huntington Disease updates
14. Neuroinflammation in neurodegeneration
Part-II: Gene and gene products in neurodegeneration
15. Big data and neurodegeneration disorders
16. Genomics and PD
17. RNA Binding Proteins and the Genesis of Neurodegenerative Diseases-Ahmed Moustafa, Egypt
18. Molecular Genetics of Huntington’s Disease
19. neuronopathic LSDs: opportunities and challenges
20. Nutrigenomics and PD
21. Genes and MS: updates
22. Genetic mapping and big data in ALS
Part-III: Present and future diagnostic approaches of neurodegenerative disorders
23. Biomarkers in AD
24. Biomarkers of PD
25. HMGB complex in PD diagnosis
26. Psychological assessment of PD patients
Part-IV: Present and future therapeutics of neurodegenerative disorders
27. Pharmacotherapy of neurodegenerative disorders: challenges and hopes
28. Advanced Drug Delivery Nanosystems: Perspectives and Regulatory Issues
29. Towards the Development of a Device to Improve the Gait of Patients Suffering from Parkinson’s Disease
30. Developing Antisense Therapies for Neurodegenerative Diseases
31. Advances in Gene Therapies for the CNS
32. Nutrition and PD
33. Stem cell therapy in NDG disorders
Product details
Product details
- Edition: 1
- Latest edition
- Published: November 24, 2024
- Language: English
About the editor
About the editor
WM
Wael Mohamed
Dr. Wael Mohamed Yousef Mohamed is Professor of Basic Medical Science at the International Islamic University Malaysia, with over 20 years of experience in translational brain research and longevity science. He earned his MD and MSc in Clinical Pharmacology from Meoufia Medical School, Egypt, and his PhD in Neuroscience from The Pennsylvania State University. His research focuses on aging-related neurodegeneration, particularly Alzheimer’s and Parkinson’s diseases, aiming to understand the biological mechanisms of aging and develop therapies to extend healthspan. Dr. Mohamed investigates how aging influences neurodegenerative processes and seeks targeted interventions to promote healthy longevity. He is a member of leading neuroscience societies, including the Society for Neuroscience. His prior editorial work with Elsevier includes titles on neurodegenerative and movement disorders, reflecting his expertise in aging, neurodegeneration, and longevity.
Affiliations and expertise
Neuroscientist and Pharmacologist, Kulliyyah of Medicine, International Islamic University Malaysia; Founder and Chair, AfrAbia PD Genomic Consortium, MalaysiaView book on ScienceDirect
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