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Elsevier

Exosomal RNA

Role in Human Diseases and Therapy

  • 1st Edition - March 29, 2024
  • Latest edition
  • Editors: Debalina Bhattacharya, Mainak Mukhopadhyay, Kursad Turksen
  • Language: English

Exosomal RNA: Role in Human Diseases and Therapy provides an in-depth study of exosomes and their RNA in the context of a variety of diseases. The book explores the diagnosti… Read more

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Description

Exosomal RNA: Role in Human Diseases and Therapy provides an in-depth study of exosomes and their RNA in the context of a variety of diseases. The book explores the diagnostic and therapeutic potential of exosomal RNA as biomarkers across a range of different conditions, including cancer, type 2 diabetes, cardiovascular and renal disease, as well as bacterial infections and tissue repair. The link between exosomal RNA expression and neurodegenerative disease is also explored. The book goes on to share the significance of exosomal RNA in preserving cellular function, with special attention given to their role in the autophagy process.

This book also gives an overview of the isolation, characterization, and potential applications of exosomal RNA, providing researchers with an understanding of how they can be manipulated and utilized for the treatment of various diseases and conditions. This is an ideal reference for researchers in the field of molecular biology, cell biology, and related fields, as well as those involved in the development of therapeutics and personalized medicine.

Key features

  • Provides an introduction into exosomal RNA and their potential as predictive and diagnostic biomarkers for various conditions
  • Considers exosomal RNA in a variety of human disorders, including metabolic diseases, inflammatory diseases, and cancer
  • Discusses the role of exosomal RNA in preserving the cellular environment and its role in the autophagy process

Readership

Researchers and postgraduate students in the field of molecular biology, cell biology, therapeutics and related fields, Clinicians working with exosomes and exosomal RNA across different disease settings

Table of contents

1. Exosomal RNA: An Introduction

2. Biogenesis of exosome and exosomal RNA and its characterization

3. Exosomal RNA in cancer progression

4. Exosomal RNA as biomarker in cancer diagnostics and therapy

5. Exosomal RNA and autophagy

6. Exosomal RNA in type

2 diabetics and other metabolic diseases

7. Exosomal RNA in immunological diseases

8. Extracellular vesicles (EVs) and their connection with brain immune cells in the context of neurodegenerative diseases

9. Exosomal RNA in aging related diseases

10. Exosomal RNA in cardiovascular diseases

11. Exosomal RNA in renal diseases

12. Exosomal RNA in bacterial infections

13. Role of Exosomal RNA in wound healing and tissue repair

14. Role of Exosomal RNA in other diseases

Product details

  • Edition: 1
  • Latest edition
  • Published: March 29, 2024
  • Language: English

About the editors

DB

Debalina Bhattacharya

Debalina Bhattacharya is currently working as an Assistant Professor in the Department of Microbiology, Maulana Azad College, West Bengal, India. Previously, she worked as a postdoctoral fellow in the Department of Biotechnology and Department of Biochemistry, University of Calcutta, West Bengal, India. She holds a PhD in bionanotechnology from Jadavpur University, West Bengal, India. She has been awarded UGC DS Kothari Post-Doctoral Fellowship in 2015 and DST-SERB National Post-Doctoral fellowship in 2018. She has co-authored 24 peer-reviewed research articles and review articles and 17 book chapters. She has also previously co-edited a book with Elsevier, "Exosomal RNA: Role in Human Diseases and Therapy".
Affiliations and expertise
Assistant Professor, Department of Microbiology, Maulana Azad College, Kolkata, West Bengal, India

MM

Mainak Mukhopadhyay

Dr. Mainak Mukhopadhyay is currently working as Associate Professor at the Department of Biosciences, JIS University, Kolkata, India. Previously, he worked as a research fellow at ONGC Energy Centre, Delhi, India. He holds a PhD in Bioenergy from the Agricultural and Food Engineering Department, Indian Institute of Technology Kharagpur, India. He has been awarded the Petrotech Research Fellowship in 2008. In 2016 he was awarded the Early Career Research Award from DST-SERB. In addition to editing two books, he has co-authored 13 peer-reviewed papers, 19 book chapters and filled 3 patents. He has also co-edited another book with Elsevier, "Exosomal RNA: Role in Human Diseases and Therapy".
Affiliations and expertise
Associate Professor, Department of Biosciences, JIS University, Agarpara, Kolkata, India

KT

Kursad Turksen

Professor Kursad Turksen received his PhD from the University of Toronto in the area of osteoprogenitor biology and cell selection methodologies. He then did postdoctoral training at the Howard Hughes Medical Institute, University of Chicago, USA, studying epidermal biology through the use of genetically-altered mouse models. He joined the Ottawa Hospital Research Institute where he rose to the position of Senior Scientist in the Division of Regenerative Medicine. His research interests focus on stem cell biology, with a particular interest in the Claudin family of tight junction proteins and their role in epidermal lineage commitment and progression during development in health and disease. Dr. Turksen is currently series editor of Stem Cells and Regenerative Medicine (Springer Nature) and Cell Biology and Regenerative Medicine (Springer Nature).
Affiliations and expertise
Senior Scientist, Ottawa Hospital Research Institute, Ottawa

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