Genome Damage
Repair and Adaptation Across Life
- 1st Edition - September 1, 2026
- Latest edition
- Editors: Vinod K. Kannaujiya, Ganesh K. Maurya, Rajesh P. Rastogi
- Language: English
Genome Damage: Repair and Adaptation Across Life explores the significance of nucleic acid damage from environmental pollutants, UV radiation, and other stressors that can lead t… Read more
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Description
Description
Genome Damage: Repair and Adaptation Across Life explores the significance of nucleic acid damage from environmental pollutants, UV radiation, and other stressors that can lead to mutations, genetic instability, and various diseases, including cancer. This book delves into the mechanisms of DNA and RNA repair, which are crucial for maintaining cellular health and enabling evolutionary adaptations. It examines these intricate processes across microbes, plants, and animals, providing a comprehensive understanding of how genetic materials are regulated and repaired under diverse environmental conditions.
Other sections cover a wide range of topics, including advanced molecular mechanisms of nucleotide repair, UV-induced damage, apoptosis cell death and autophagy, genetic instability in crops, and the role of post-translational modifications in DNA repair, the detection and quantification of DNA damage, the impact of synthetic chemicals and climate change on nucleic acids, and the therapeutic significance of DNA repair mechanisms. The book closes with a look towards future perspectives.
Other sections cover a wide range of topics, including advanced molecular mechanisms of nucleotide repair, UV-induced damage, apoptosis cell death and autophagy, genetic instability in crops, and the role of post-translational modifications in DNA repair, the detection and quantification of DNA damage, the impact of synthetic chemicals and climate change on nucleic acids, and the therapeutic significance of DNA repair mechanisms. The book closes with a look towards future perspectives.
Key features
Key features
- Covers nucleic acid damage and repair mechanisms across a range of organisms
- Provides insights into environmental adaptability and the evolutionary significance of genetic mutations
- Discusses detection and prevention strategies for DNA damage
- Offers therapeutic applications for genetic disorders, including cancer and aging-related diseases
Readership
Readership
Molecular biologists and advanced students working with DNA damage and repair of microbial, plant and animal communities; Students and researchers across cytogenetics, evolutionary biology, microbiology, ecotoxicology, plant biotechnology, pharmaceutical science and related areas
Table of contents
Table of contents
1. Genome research: basic concept and recent advances
2. Nucleotide repair mechanism: fundamental to molecular advances
3. Nucleotide damage and its role in the evolution of microbes
4. UV mediated damage and repair in bacterial communities
5. Oxidative stress and nucleotide mutagenesis in microbes
6. DNA Photolyase: Properties and mode of action
7. DNA repair in extremophiles
8. Genetic instability in crop plants: evolution and modern perspectives
9. UV-induced DNA damage and repair in higher plants
10. Ionizing radiation induced mammalian cell damage and repairs
11. Non ionizing radiation induced DNA damage and repair in animals
12. Oxidative DNA damage: repair mechanisms and associated disorder in humans
13. Responses of cell checkpoint on DNA mutagenesis
14. DNA damage and autophagy: mechanisms and significance
15. Role of Post translational modification in DNA repair
16. Detection of DNA damage and repair: a technological development
17. Cellular quantification of DNA damage and its repair
18. Eco-toxicity of synthetic chemicals and DNA health
19. Effects of climate change on nucleic acid composition
20. RNA damage and repair mechanism
21. DNA damage and cancer: advances, risk assessment and opportunities
22. Metal stress and DNA mutagenesis
23. Recent development in photonic induced photorepair mechanism
24. Apoptosis cell death and DNA damage
25. Significance of plant nutraceuticals in DNA repair
26. Significance of algal green chemicals in repair mechanism
27. DNA damage and repair: a disease specific therapeutic significance
28. DNA damage and aging: Concept, feasibility, and significance
29. SOS response and molecular check point repair
30. DNA damage and recombination repair during DNA replication
31. Structural and dynamical signatures of DNA damage
32. Impacts of nanoparticles on DNA damage and repair
33. Bioprospecting of active metabolites for repair of DNA damage
34. DNA photosensitization-application and future perspectives
35. DNA damage and repair: Future perspectives
2. Nucleotide repair mechanism: fundamental to molecular advances
3. Nucleotide damage and its role in the evolution of microbes
4. UV mediated damage and repair in bacterial communities
5. Oxidative stress and nucleotide mutagenesis in microbes
6. DNA Photolyase: Properties and mode of action
7. DNA repair in extremophiles
8. Genetic instability in crop plants: evolution and modern perspectives
9. UV-induced DNA damage and repair in higher plants
10. Ionizing radiation induced mammalian cell damage and repairs
11. Non ionizing radiation induced DNA damage and repair in animals
12. Oxidative DNA damage: repair mechanisms and associated disorder in humans
13. Responses of cell checkpoint on DNA mutagenesis
14. DNA damage and autophagy: mechanisms and significance
15. Role of Post translational modification in DNA repair
16. Detection of DNA damage and repair: a technological development
17. Cellular quantification of DNA damage and its repair
18. Eco-toxicity of synthetic chemicals and DNA health
19. Effects of climate change on nucleic acid composition
20. RNA damage and repair mechanism
21. DNA damage and cancer: advances, risk assessment and opportunities
22. Metal stress and DNA mutagenesis
23. Recent development in photonic induced photorepair mechanism
24. Apoptosis cell death and DNA damage
25. Significance of plant nutraceuticals in DNA repair
26. Significance of algal green chemicals in repair mechanism
27. DNA damage and repair: a disease specific therapeutic significance
28. DNA damage and aging: Concept, feasibility, and significance
29. SOS response and molecular check point repair
30. DNA damage and recombination repair during DNA replication
31. Structural and dynamical signatures of DNA damage
32. Impacts of nanoparticles on DNA damage and repair
33. Bioprospecting of active metabolites for repair of DNA damage
34. DNA photosensitization-application and future perspectives
35. DNA damage and repair: Future perspectives
Product details
Product details
- Edition: 1
- Latest edition
- Published: September 1, 2026
- Language: English
About the editors
About the editors
VK
Vinod K. Kannaujiya
Dr. Vinod Kumar Kannaujiya is an assistant professor in the Department of Botany, MMV, Banaras Hindu University, India. He earned his MSc and PhD degrees in Botany from the Centre of Advanced Study in Botany, Banaras Hindu University. He has been working on the ultraviolet stress response of cyanobacteria including value-added enzymes, proteins, pigments, and natural compounds. He has been awarded with prestigious fellowships from the Council of Scientific and Industrial Research, New Delhi, India. He has also been awarded the Dr. D.S. Kothari Post-Doctoral Fellowship from University Grant Commission, New Delhi, India, and he has received a UGC-Startup project grant from UGC, New Delhi, India. Dr. Kannaujiya is a life member fellow of the Indian Photobiology Society. Thus far, Dr. Kannaujiya has published over 49 original research papers, reviews, and book chapters.
Affiliations and expertise
Assistant professor, Department of Botany, MMV, Banaras Hindu University, IndiaGM
Ganesh K. Maurya
Dr. Ganesh Kumar Maurya is an assistant professor in the Department of Zoology, MMV, Banaras Hindu University, Varanasi, India. He received his M.Sc. degree in Zoology from the Centre of Advanced Study in Zoology, Banaras Hindu University, Varanasi, India and Ph.D. in Life Science from Bhabha Atomic Research Centre, HBNI, Mumbai, India. He has been working on genome maintenance under oxidative stress including Gamma radiation in the polyextremophile Deinococcus radiodurans. Beside this, he is also working on the antibiotic resistance and phage therapy against the pathogenic bacteria. He has received gold medals in M.Sc. and Ph.D. He is the recipient of a prestigious ‘Young Scientist Award from National Academy of Sciences, India’. He is also the recipient of UGC-Startup, SRG-SERB, IoE project grant from various funding agencies. He is a life member fellow of the Society of Biological Chemist (India). He has published over 25 original research papers, reviews, and book chapters.
Affiliations and expertise
Assistant Professor Department of Zoology, MMV, Banaras Hindu University, Varanasi, IndiaRR
Rajesh P. Rastogi
Dr. Rajesh P Rastogi is currently working as a Scientist/Joint Director at the Ministry of Environment, Forest and Climate Change, New Delhi, India. He completed his Ph. D. on UV-induced DNA Damage and Repair at Banaras Hindu University, Varanasi, India. Dr. Rastogi is the recipient of some national and international awards and fellowships. He was a visiting scientist at Friedrich Alexander University, Nuremberg, Germany and served as a visiting professor of biochemistry at Chulalongkorn University, Thailand. His major research areas are freshwater or marine algae and cyanobacterial ecology and biotechnology, plant physiology, photochemistry, photobiology, molecular microbiology and stress biology. Dr. Rastogi has already published more than 100 referred international peer reviewed research papers, review articles in high impact journals of international repute. He has also published several book chapters and five books from renowned international publishers (Elsevier/Springer/Nova). He is serving as an editorial board member of some national and international journals and is life member of several scientific organizations.
Affiliations and expertise
Scientist/Joint Director Environment Impact Assessment Division, Ministry of Environment, Forest and Climate Change, New Delhi, India