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Heavy Metal Toxicity and Neurodegeneration

  • 1st Edition - August 13, 2025
  • Latest edition
  • Editors: Prasann Kumar, Neha Gogia
  • Language: English

Heavy Metal Toxicity and Neurodegeneration delves into the intricate relationship between heavy metals and neurodegenerative diseases. It synthesizes and presents the latest resear… Read more

Description

Heavy Metal Toxicity and Neurodegeneration delves into the intricate relationship between heavy metals and neurodegenerative diseases. It synthesizes and presents the latest research findings, shedding light on the mechanisms by which heavy metals cause neuronal damage and contribute to disease progression. By integrating various perspectives and collating diverse studies, this book serves as an invaluable resource for those seeking to understand the profound impact of heavy metals on neurological health. In addition to detailing the mechanisms involved, the book highlights the importance of early detection and preventive measures.

It caters to researchers, clinicians, policymakers, and students, offering a comprehensive and accessible overview that bridges the gap between theory and practical application. This scholarly work is poised to inform and guide future research and policy decisions in the field of neurodegenerative disease.

Key features

  • Provides a comprehensive overview of how heavy metals interact with biological systems, particularly the nervous system
  • Explains the mechanisms through which metals contribute to neurodegenerative diseases
  • Highlights the public health implications of heavy metal exposure, including its impact on vulnerable populations such as children and older people

Readership

Researchers and clinicians interested in neurodegenerative diseases, neurology, public health and toxicology

Table of contents

1. Biological pathways of heavy metal toxicity
Mridu Kulwant and Divya Patel

2. Mechanisms of neurodegeneration induced by heavy metals
Prasann Kumar

3. Lead toxicity and its impact on cognitive function
K. Jaisuriyan and Prasann Kumar

4. Mercury poisoning: effects on the central nervous system
Neha Gogia and Prasann Kumar

5. Arsenic exposure and neurotoxic effects
Prasann Kumar

6. Cadmium and its role in neurodegenerative diseases
Prasann Kumar

7. Chromium toxicity: neurological implications
Prasann Kumar

8. Interactions between heavy metals and neuroinflammatory processes
Debjani Choudhury and Prasann Kumar

9. Oxidative stress and heavy metal induced neuronal damage
Patan Ruksar and Prasann Kumar

10. Genetic susceptibility to heavy metal toxicity
Prasann Kumar

11. Role of glutathione in heavy metal detoxification
Prasann Kumar

12. Heavy metals and Alzheimer’s disease: a review
Bushra Bashir, Sapna Jarial, Shivalika Sood and Sukriti Vishwas

13. Parkinson's disease and heavy metal exposure
Amit Raj and Prasann Kumar

14. Multiple sclerosis: the impact of heavy metals
Prabhjot Singh Jassal and Tusha Yadav

15. Heavy metals and amyotrophic lateral sclerosis
Amit Raj and Prasann Kumar

16. Neurodevelopmental disorders linked to heavy metal exposure
Mastu Patel and Prasann Kumar

17. Childhood exposure to heavy metals and long-term neurodevelopmental effects
Mastu Patel and Prasann Kumar

18. Environmental sources of heavy metals and their impacts on human health
Monika Sharma and Prasann Kumar

19. Biomarkers of heavy metal–induced neurotoxicity: insights into mechanisms and disease impact
Krupanshi Bharadava, Sanjay Kumar and Radhey Shyam Kaushal

20. Diagnostic techniques for heavy metal induced neurotoxicity
Prasann Kumar

21. Prevention and mitigation strategies for heavy metal exposure
Makey Sri Chakra Naga Vardhan, Ashok S. Dambale, Prasann Kumar and Nilabja Banerjee

22. Therapeutic approaches for heavy metal detoxification
Prasann Kumar

23. Dietary interventions for reducing heavy metal toxicity
Prasann Kumar and Shipa Rani Dey

24. Pharmacological treatments for neurodegeneration due to heavy metals
Prasann Kumar

25. The role of chelation therapy in heavy metal detoxification
Venkata Suneel Kumar Velugolu and Prasann Kumar

26. Impact of heavy metals on neuroplasticity
Prasann Kumar and Shipa Rani Dey

27. Heavy metal toxicity and psychiatric disorders
Debjani Choudhury and Prasann Kumar

28. Epidemiological studies on heavy metal exposure and neurodegeneration
Debjani Choudhury and Prasann Kumar

29. Regulatory standards and guidelines for heavy metal exposure
B. Gopika and Prasann Kumar

Product details

  • Edition: 1
  • Latest edition
  • Published: August 14, 2025
  • Language: English

About the editors

PK

Prasann Kumar

Dr. Prasann Kumar, assistant professor cum research intensive faculty in the Department of Agronomy, School of Agricultural (ICAR-Accredited), Lovely Professional University, Punjab, specializes in stress physiology, plant tissue culture, physiology of plantmicrobe/pathogen interaction, and biodiversity management. Dr. Kumar has completed the International Agricultural Rural Development Programme from Cornell University, Ithaca, New York, United States. He has received a doctorate from Banaras Hindu University, Varanasi. He also has authored 40 books published by national and international publishers, which find a place in national as well as various Overseas Institutions’ libraries. He has guided 19 MSc students for their thesis.
Affiliations and expertise
Assistant Professor, Department of Agronomy, School of Agricultural (ICAR-Accredited), Lovely Professional University, Punjab, India

NG

Neha Gogia

Dr. Gogia is a Post-Doctoral Associate at Yale. Having completed her PhD degree at the University of Dayton, and Cornell University’s International Agriculture and Rural Development Program (IARD) she was awarded the Gerald L. Willis Award of Excellence for Outstanding Teaching in 2019. Her current work focuses on understanding cellular and molecular mechanisms underlying polyglutamine diseases, namely the identification and validation of genetic modifiers which can serve as potential therapeutic targets and can ameliorate the onset or progression of neurodegenerative diseases.
Affiliations and expertise
Post-Doctoral Associate, Yale University, Connecticut, USA

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