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Human Organs-on-a-Chip Technology

  • 1st Edition - June 18, 2024
  • Latest edition
  • Editor: P.V. Mohanan
  • Language: English

Human Organs-on-a-Chip Technology focuses on technology advancement from “organ-on-a-chip”, “multi organs-on-a-chip”, and the newest stage of “human organs-on-a-chip." Chap… Read more

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Description

Human Organs-on-a-Chip Technology focuses on technology advancement from “organ-on-a-chip”, “multi organs-on-a-chip”, and the newest stage of “human organs-on-a-chip." Chapters investigate the design, simulation studies, device development, and application of microfluidic systems. In addition, they offer expert perspectives on the development of an alternative test system in the biological evaluation of drugs, cosmetics, chemicals, medical devices, and many others. Lastly, the book addresses issues related to the development of microfluidic devices and alternative test systems in biological and biomedical research.

Key features

  • Explores organs-on-a-chip technology, from the basics, to advanced developments and existing challenges and recent research trends and applications
  • Reviews every aspect of microfluidic devices, including biological evaluation and targeted delivery
  • Includes the latest information on regulatory updates

Readership

Graduate students, researcher, and professionals in biomedical engineering

Table of contents

1. Basics of Microfluidics technology

2. The Physics and Engineering of Flow in Organ on a Chip Devices

3. Importance of Soft lithography

4. Development of microfluidic devices

5. Microfluidics based point of care devices

6. Microfluidics, Organs-on-a-chip and 3D printing

7.Microfluidic platforms: applications and challenges

8. Design and simulation study of Organ-on-a-chip

9. Primary Cell culture for Organ-on-a-chip

10. Vascularisation in organs-on-a-chip

11. Organ-on-a-chip in nanotechnology

12. Organs-on-a-chip in precision medicine

13. Foeto-placental organ-on-a-chip

14. Organs-on-a-chip in drug development

15. Organ-on-a-chip for multianalyte monitoring

16. Organ-on-a-chip for Blood-brain-barrier studies

17. Organs on a chip models for sensor

18. Innovative ‘organs-on-a-chip’ technology for marine drug development

19. Exposure-on-a-chip as a model for inhalation toxicology and pharmacology research

20. Brain-on-chip

21. Recent breakthrough in organ-on-a-chip

22. 3D printed microfluidic chips

23. 3D tissue and Organ-on-a-chip models

24. Vascularisation of organoids in microfluidic chips

25. Multiorgans-on-a-chip: Design and applications

26. Multiorgans-on-a-chip for subacute toxicity

27. Multiorgans-on-a-chip for acute toxicity

28. Human organs-on-a-chip for biological evaluation

29. Human organs-on-a-chip for cancer modelling

Product details

  • Edition: 1
  • Latest edition
  • Published: June 18, 2024
  • Language: English

About the editor

PM

P.V. Mohanan

Dr. Mohanan FNASc, is the Head of the Division of Toxicology, Sree Chitra Tirunal Institute for Medical Sciences and Technology (Govt. of India). He is a visiting professor and visiting researcher at Toyo University, Japan and a Certified Biological Safety Specialist. Previously, he was a JSPS Post doctoral Fellow at the University of Tsukuba, Japan in the field of Neurotoxicity. He joined Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Govt. of India in 1989 and has spent 33 years of professional life working there. As a toxicologist he has been intimately associated with all the medical devices/technologies developed at SCTIMST. He received the lifetime achievement award from the Society of Toxicology India, for the outstanding contribution in the field of toxicology. He also patented an ELISA kit for the measurement of pyrogenicity. Mohanan made significant contributions for the development of medical device regulations in India. He has authored 231 publications and edited 6 books. Presently he is the secretary general of the Society of Toxicology, India.
Affiliations and expertise
Scientist-G and Head, Toxicology Division, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Govt. of India, India

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