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Hypercortisolism: Diagnosis and Differential Diagnosis

  • 1st Edition, Volume 132 - June 1, 2026
  • Latest edition
  • Editor: Marta Araujo Castro
  • Language: English

Hypercortisolism: Diagnosis and Differential Diagnosis, Volume 132 presents a comprehensive series of chapters focused on the various aspects of endogenous hypercortisolism as con… Read more

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Description

Hypercortisolism: Diagnosis and Differential Diagnosis, Volume 132 presents a comprehensive series of chapters focused on the various aspects of endogenous hypercortisolism as contributed by an international team of specialists in endocrinology. Chapters in this new release include Cushing´s syndrome: Clinical presentation and associated comorbidities, Biochemical diagnosis of hypercortisolism: when and how?, ACTH independent Cushing syndrome: diagnosis and etiology, Bilateral macronodular and micronodular hyperplasia: biochemical, radiological and genetic diagnosis, Differential diagnosis between endogenous Cushing´s syndrome and pseudoCushing, and much more.

Additional chapters delve into Differential diagnosis of ACTH dependent Cushing´s syndrome: hormonal and radiological studies, Ectopic Cushing´s syndrome: clinical presentation and diagnosis, Cyclic Cushing´s syndrome, Mild autonomous cortisol secretion: diagnosis, Cushing´s syndrome and pregnancy: clinical presentation and diagnosis, Molecular profile of Cushing´s syndrome, Cardiometabolic comorbidities in overt Cushing´s syndrome, and New tools for the diagnosis of hypercortisolism.

Key features

  • Includes tactics on the proper diagnosis of hypercortisolism, a serious, multisystemic disease that, if left untreated, can lead to severe complications and increased mortality, including cardiovascular events, diabetes, and infections
  • Covers the diagnosis of hypercortisolism and how it is complex due to non-specific symptoms, the existence of multiple potential causes, and the variability of test results
  • Distinguishes between true hypercortisolism and conditions with similar symptoms, including their differences, especially in cases like subclinical, cyclic or pseudo-Cushing's syndrome

Readership

For the following medical specialties: Endocrinology, Internal Medicine, Clinical biochemical, Genetics; and Family Medicine

Table of contents

1. Cushing´s syndrome: Clinical presentation and associated comorbidities.
Alín Abreu Lomba

2. Biochemical diagnosis of hypercortisolism: when and how?
Anna Aulinas Masó

3. ACTH independent Cushing syndrome: diagnosis and etiology
Andres Ortiz

4. Bilateral macronodular and micronodular hyperplasia: biochemical, radiological and genetic diagnosis
Víctor Navas Moreno Sr., Mónica Marazuela, Carolina Sager La Ganga and María Sara Tapia Sanchiz

5. Differential diagnosis between endogenous Cushing´s syndrome and pseudoCushing
Ahmed Alaa Abdul-Aziz

6. Differential diagnosis of ACTH dependent Cushing´s syndrome: hormonal and radiological studies
Wilfredo Antonio Rivera Martín

7. Ectopic Cushing´s syndrome: clinical presentation and diagnosis
Valentina Morrelli and Antonio Musolino

8. Cyclic Cushing´s syndrome
Elisabeth Nowak

9. Mild autonomous cortisol secretion: diagnosis
Sara Donato

10. Cushing´s syndrome and pregnancy: clinical presentation and diagnosis
Betina Biagetti Sr.

11. Molecular profile of Cushing´s syndrome
Alejandro Ibáñez-Costa and Justo Castaño

12. Cardiometabolic comorbidities in overt Cushing´s syndrome
Laura Gonzalez

13. New tools for the diagnosis of hypercortisolism
Felicia A. Hanzu and Felicia Alexandfra Hanzu

Product details

  • Edition: 1
  • Latest edition
  • Volume: 132
  • Published: June 1, 2026
  • Language: English

About the editor

MC

Marta Araujo Castro

Marta Araujo-Castro, MD., PhD., is an endocrinologist of the Endocrinology and Nutrition Department of the Ramón y Cajal University Hospital in Madrid, Spain. She is the coordinator of the Neuroendocrinology & Adrenal Unit of the Endocrinology Department of her hospital. Her main clinical focus and research is on pituitary and adrenal gland disorders. She is the principal investigator and coordinator of the ACRO-SPAIN Registry, the SPAIN-ALDO Registry and the PHEO-PARA-RISK Study of the Spanish Society of Endocrinology & Nutrition (SEEN). Furthermore, in the last years she has received several awards related to adrenal and pituitary disorders (Cushing´s syndrome, acromegaly, adrenal incidentalomas, pheochromocytomas and so on). She is the current coordinator of the adrenal diseases group of the SEEN, a member of the scientific board of the working group of Aldosterone Producing Adenomas (APA) of ENSAT, coordinator of the Pituitary Committee of the Ramón y Cajal University Hospital and the principal investigator of the group of Endocrine-Metabolic, Digestive and Nutrition Surgery of the Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS).

She has more than 150 Medline listed manuscripts, cited >1000 times. More information

Dr. Araujo-Castro is a member of the SEEN, the European Endocrine Society (ESE), Spanish Group of Neuroendocrine Tumors (GETNE), European Network for the Study of Adrenal Tumors (ENSAT), Endocrine Society, SEEN and other many medical societies.

She actively participates in several national and international congresses with presentations related to adrenal pathology. Moreover, Dra. Araujo-Castro is a professor of the master’s degree in Endocrine Oncology Pathology at TECH University; she holds the title of master’s degree in research Methodology in Health Sciences of the Laboratory of Applied Statistics of the Autonomous University of Barcelona (UAB) (Spain) and the Diploma in Statistics in Health Sciences of the UAB.

about my professional profile below:

Researchgate: https://www.researchgate.net/profile/Marta-Araujo-Castro

Twitter: Marta_Araujo_C

ORCID: https://orcid.org/0000-0002-0519-0072

Affiliations and expertise
Ramón y Cajal University Hospital, Madrid, Spain