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Elsevier

Inflammation and Natural Products

  • 1st Edition - January 19, 2021
  • Latest edition
  • Editors: Sreeraj Gopi, Augustine Amalraj, Ajaikumar B. Kunnumakkara, Sabu Thomas
  • Language: English

Inflammation and Natural Products brings together research in the area of the natural products and their anti-inflammatory action in medical, nutraceutical and food products,… Read more

Description

Inflammation and Natural Products brings together research in the area of the natural products and their anti-inflammatory action in medical, nutraceutical and food products, addressing specific chronic inflammatory diseases like cancer and the mechanistic aspects of the mode of action of some key natural products. Inflammation is a complicated process, driven by infection or injury or genetic changes, which results in triggering signalling cascades, activation of transcription factors, gene expression, increased levels of inflammatory enzymes, and release of various oxidants and pro-inflammatory molecules in inflammatory cells. Excessive oxidants and inflammatory mediators have a harmful effect on normal tissue, including toxicity, loss of barrier function, abnormal cell proliferation, inhibiting normal function of tissues and organs and finally leading to systemic disorders. The emerging development of natural product formulations utilizing the unique anti-inflammatory compounds such as polyphenols, polysaccharides, terpenes, fatty acids, proteins and several other bioactive components has shown notable successes. Inflammation and Natural Products: Recent Development and Current Status provides a comprehensive resource, ranging from detailed explanation on inflammation to molecular docking strategies for naturally occurring compounds with anti-inflammatory activity. It is useful for graduate students, academic and professionals in the fields of pharmaceutical and medical sciences and specialists from natural product-related industries.

Key features

  • Increases the knowledge of anti-inflammatory activities of natural products and their mechanism of action
  • Provides a new perspective and forward-thinking ideas to researchers, the scientific community and industry
  • Intensifies the understanding of synergistic action of biologically active naturally occurring molecules and their biological activities against inflammation

Readership

Graduate students, academics and professionals in the fields of pharmaceutical and medical sciences and specialists from natural products-related industry

Table of contents

1. Inflammation - Symptoms, Reactions and Biochemistry

2. Molecular and genetic inflammation networks in major human diseases

3. Natural products in inflammation: The emerging trends and prospective goals

4. Natural products as modulator of signaling in inflammation

5. Natural products with anti-inflammatory activities against autoimmune myocarditis

6. Multi-target approach for natural products in inflammation

7. Anti-inflammatory activity of natural dietary flavonoids

8. Anti-inflammatory effects of turmeric and ginger

9. Potential anti-inflammatory natural products from marine algae

10. Natural product derived drugs for the treatment of inflammatory bowel diseases

11. Smart drug delivery systems of natural products for inflammation: from fundamentals to the clinic

12. Systems pharmacology and molecular docking strategies prioritize natural molecules as anti-inflammatory agents

13. Formulations, supplements and diets for anti-inflammation

14. Values of natural products to future anti-inflammatory pharmaceutical discovery

15. Metabolomic study of natural products in toxicity evaluation and toxicology biomarker identification

Product details

  • Edition: 1
  • Latest edition
  • Published: January 21, 2021
  • Language: English

About the editors

SG

Sreeraj Gopi

Dr. Sreeraj Gopi is the Co-Founder and Director of Molecules Food solutions Pvt Ltd, Zingon Naturals Pvt Ltd. He was the Chief Scientist at Plant Lipids Pvt Ltd. and Chief Scientific Officer at Aurea Biolabs Pvt Ltd., He has also served as an adjunct professor at universities including Stockholm University, Sweden, Siberian Federal University, Russia, and Mahatma Gandhi University, India. He completed his doctorate in organic chemistry and nanotechnology, and nano drug delivery working in the area of natural products, isolation, and biological activities. He published more than 175 international articles and filed more than 75 patents, in the US and Europe. At Plant Lipids, he developed many innovative products and technologies, and is responsible for driving the research team to excellence, as well as, implementing new projects, presenting scientific seminars to various customers. He was listed world's top 2% scientist list by Standford University.

Affiliations and expertise
Co-Founder and Director of Molecules Food Solutions Pvt Ltd, Zingon Naturals Pvt Ltd., India

AA

Augustine Amalraj

Dr. Augustine Amalraj is currently working as a Senior Scientist in the Department of Research and Development at Molecules Food Solutions Private Limited, Koratty, Thrissur, Kerala, India. He was worked as a Deputy Manager in the Department of Research and Development at Plant Lipids Private Limited and Aurea Biolabs Private Limited, Cochin, India. He obtained his Doctoral degree in Chemistry from Gandhigram Rural Institute – Deemed University, Gandhigram, Tamil Nadu, India. His research interests are in applied chemistry, food chemistry, natural product chemistry, environmental chemistry, chemosensors, and polymer and nanocomposite materials. He has published more than 60 research articles in international journals, as well as 22 book chapters, co-edited 10 books and filed 3 patents. He was listed among the top 2% of scientists in the world by Stanford University.
Affiliations and expertise
Senior Scientist, Department of Research and Development, Molecules Food Solutions Private Limited, Kerala, India

AK

Ajaikumar B. Kunnumakkara

Prof. Ajaikumar Kunnumakkara, is a faculty member in the Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Assam, India. He is also an Honorary Chair Professor in Nanoscience and Nanotechnology. He is the principal investigator of Unit of Excellence in cancer drug discovery (DBT, Govt. of India) and the coordinator of DBT (India) - AIST (Japan) International Laboratory for Advanced Biomedicine. He earned his doctorate in 2006 from Amala Cancer Research Center, Thrissur, affiliated with University of Calicut, Kerala, India. Dr. Kunnumakkara did postdoctoral work at the University of Texas MD Anderson Cancer Center, Houston, Texas, USA (2005–2008) and the National Cancer Institute of National Institutes of Health (2008–2010) where he was subsequently employed as an NIH Scientist until 2012. Dr. Kunnumakkara has also edited four monographs. He is an elected Fellow of Royal Society of Medicine, UK as well as belonging to many other esteemed institutions.
Affiliations and expertise
Indian Institute of Technology Guwahati, India

ST

Sabu Thomas

Prof. Sabu Thomas is a globally renowned scientist and one of the leading researchers in polymer science and nanotechnology. He currently serves as Professor of Polymer Science & Engineering and was the former Vice Chancellor of Mahatma Gandhi University, Kerala, India. Prof. Thomas is internationally recognized for his pioneering work on polymer blends, nanocomposites, green materials, and sustainable polymers.

Affiliations and expertise
Professor, Mahatma Gandhi University, Kottayam, Kerala, India; Department of Physics and Electronics, Christ University, Bangalore, India; Center of Excellence in Polymeric Materials for Medical Practice Devices, Department of Chemical Engineering, Faculty of Engineering, Chulalongkorn University, Bangkok, Thailand; TrEST Research Park, Trivandrum, Kerala, India

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