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Ionotropic Cross-Linking of Biopolymers

Applications in Drug Delivery

  • 1st Edition - April 15, 2024
  • Latest edition
  • Editors: Amit Kumar Nayak, Md Saquib Hasnain
  • Language: English

Ionotropic Cross-Linking of Biopolymers: Applications in Drug Delivery provides in-depth insights and presents the latest advances in ionotropic cross-linked biopolymeric system… Read more

Description

Ionotropic Cross-Linking of Biopolymers: Applications in Drug Delivery provides in-depth insights and presents the latest advances in ionotropic cross-linked biopolymeric systems for drug delivery and related applications. Sections introduce the fundamentals of ionotropic cross-linking of biopolymers, including mechanisms, chemistry, cross-linking methods and gelation. Additional content delves into ionotropically cross-linked biopolymers based on a range of sources, including alginate, pectinate, carboxymethyl cellulose, gellan gum, chitosan, carboxymethylated gums, plant polysaccharide blends, and synthetic polymer blends. This is followed by a section focusing on ionotropically cross-linked biopolymeric systems, such as polymeric nanoparticles, microparticles, beads, and reinforced matrices.

The last part of the book explores specific advanced drug delivery applications, before considering future opportunities and challenges in the field. This is a valuable resource for researchers and advanced students across polymer science, biomaterials, biomedicine, pharmaceutics, biotechnology, and chemistry, as well as scientists and R&D personnel working in pharmacy, drug delivery, and materials for biomedicine.

Key features

  • Explains chemistry, mechanisms, preparation methods and applications of biopolymeric systems
  • Covers a range of biopolymer sources, including alginate, pectinate, gellan gum, chitosan, and others
  • Guides the reader to cutting-edge applications in drug delivery, drug release, cell delivery and tissue engineering

Readership

Researchers and advanced students across polymer science, biomaterials, biomedicine, pharmaceutics, healthcare, biotechnology, and chemistry, Scientists and R&D working in pharmacy, drug delivery, and materials for biomedicine

Table of contents

Section 1: Introduction and fundamentals

1. Ionotropic cross-linking of biopolymers: Basics and mechanism

2. Fundamentals and applications of ionic biopolymers

3. Ionic biopolysaccharides and their uses in ionotropically cross-linked hydrogels for controlled drug delivery

4. Ionotropic cross-linking methods of different types of biopolymeric hydrogels

5. Ionotropic gelation in advanced drug delivery

Section 2: Ionotropically cross-linked biopolymers

6. Ionotropically cross-linked alginate-based systems in drug delivery

7. Ionotropically cross-linked pectinate-based systems for drug delivery

8. Ionotropically cross-linked carboxymethyl cellulose-based systems for drug delivery

9. Ionotropically cross-linked gellan gum-based matrices in drug delivery

10. Ionotropically cross-linked chitosan-based drug delivery systems

11. Ionotropically cross-linked carboxymethylated gums-based systems in drug delivery

12. Plant polysaccharides-blended ionotropically cross-linked biopolymeric matrices for sustained drug release

13. Synthetic polymers-blended ionotropically cross-linked biopolymeric matrices for sustained drug release

Section 3: Ionotropically cross-linked biopolymeric systems

14. Ionotropically cross-linked polymeric nanoparticles for drug delivery

15. Ionotropically cross-linked polymeric microparticles for drug delivery

16. Ionotropically cross-linked polymeric beads for drug delivery

17. Clay-reinforced ionotropically cross-linked biopolymeric matrices for drug release

18. Ceramics-reinforced ionotropically cross-linked biopolymeric matrices for drug release

19. Ionotropically cross-linked interpenetrated polymeric networks for drug delivery

20. Ionotropically cross-linked biopolymeric polyelectrolyte complex matrices for drug delivery

21. Ionotropically cross-linked drug delivery carriers made of grafted biopolymers

Section 4: Specific drug delivery applications

22. Ionotropically cross-linked buoyant polymeric matrices for gastroretentive drug delivery

23. Ionotropically cross-linked polymeric matrices for colon-specific drug delivery

24. Ionotropically cross-linked polymeric particulates in mucoadhesive drug delivery

25. Ionotropically cross-linked biopolymeric carriers for protein and peptide drug delivery

26. Applications of ionotropic cross-linking of biopolymers in cell delivery

27. Ionotropic cross-linking of biopolymers for drug delivery in wound management

28. Ionotropic cross-linking of biopolymers for drug delivery in tissue engineering

29. Future perspectives, challenges, and opportunities of ionotropic cross-linking of biopolymers in drug delivery

Product details

  • Edition: 1
  • Latest edition
  • Published: April 15, 2024
  • Language: English

About the editors

AN

Amit Kumar Nayak

Amit Kumar Nayak (M. Pharm, Ph.D) is currently working as Professor at School of Pharmaceutical Sciences,Siksha ‘O' Anusandhan (Deemed to be University), Odisha, India. He has earned his PhD from IFTM University, Moradabad, Uttar Pradesh, India. He has over 14 years of research experiences in the field of pharmaceutics, especially in the development and characterization of novel biopolymeric and nanostructured drug delivery systems. Till date, he has authored more than 138 research and review publications in various high-impact peer-reviewed journals and 135 book chapters. He has edited/authored 23 international books to his credit. Dr. Nayak has presented his research work at several conferences. He has received University Foundation Day Research Award, 2019 and 2022 by Biju Patnaik University of Technology, Odisha. Dr. Nayak is a life member of the Association of Pharmaceutical Teachers of India (APTI) and a registered pharmacist.

Affiliations and expertise
Professor, Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India

MH

Md Saquib Hasnain

Md Saquib Hasnain (Ph.D) is currently working as the Professor and Dean, Department of Pharmaceutical Technology, School of Health and Medical Sciences, Barasat, Kolkata, West Bengal, India. He has over 13 years of research experience in the field of drug delivery and pharmaceutical formulation analyses, especially systematic development and characterization of diverse nanostructured drug delivery systems, controlled release drug delivery systems, bioenhanced drug delivery systems, nanomaterials and nanocomposites employing Quality by Design approaches and many more. Till date he has authored over 100 publications in various high impact peer-reviewed journals, more than 100 book chapters and 30 books to his credit. He is also serving as the reviewer of several prestigious journals. Overall, he has earned a highly impressive publishing and cited record. He has also participated and presented his research work at over ten conferences in India, and abroad. He was also a member of scientific societies i.e., Royal Society of Chemistry, Great Britain, International Association of Environmental and Analytical Chemistry, Switzerland and Swiss Chemical Society, Switzerland.
Affiliations and expertise
Department of Pharmaceutical Technology, School of Health and Medical Sciences, Adamas University, Kolkata, West Bengal, India.

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