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Machine Learning and Artificial Intelligence in Toxicology and Environmental Health

  • 1st Edition - September 15, 2025
  • Latest edition
  • Editors: Zhoumeng Lin, Wei-Chun Chou
  • Language: English

Machine Learning and Artificial Intelligence in Toxicology and Environmental Health introduces the fundamental concepts and principles of machine learning and AI, providing clear… Read more

Description

Machine Learning and Artificial Intelligence in Toxicology and Environmental Health introduces the fundamental concepts and principles of machine learning and AI, providing clear explanations on applying these methods to toxicology and environmental health. The book delves into predictions of chemical ADMET properties, development of PBPK and QSAR models, toxicogenomic analysis, and the evaluation of high-throughput in vitro assays. It aims to guide readers in adapting machine learning and AI techniques to various research problems within these fields. Additionally, the text explores ecotoxicology assessment, impacts of air pollution, climate change, food safety, and chemical risk assessment.

It includes case studies, hands-on computer exercises, and example codes, making it a comprehensive resource for researchers, academics, students, and industry professionals. The book highlights how AI can enhance risk assessment, predict environmental hazards, and speed up the identification of harmful substances.

Key features

  • Covers the basic concepts and principles of commonly used machine learning and AI methods in the field of toxicology and environmental health
  • Provides an introduction to the applications of machine learning and AI methods in toxicology and environmental health
  • Offers case studies, example codes, and hands-on computer exercises to help readers apply machine learning and artificial intelligence (AI) methods in toxicology and environmental health

Readership

Researchers, faculty, postdocs, advanced undergraduate, graduate students in the fields of toxicology, environmental health, pharmacology, biostatistics, bioinformatics, epidemiology, bioengineering; Industry professionals from consulting companies, pharmaceutical and chemical industry, and state and federal public health agencies

Table of contents

1. Applications of machine learning and artificial intelligence in toxicology and environmental health

2. Basics of machine learning and artificial intelligence methods in toxicology and environmental health

3. Application of machine learning and artificial intelligence methods in predictions of absorption, distribution, metabolism, excretion properties of chemicals

4. Application of machine learning and artificial intelligence methods in physiologically based pharmacokinetic modeling

5. Machine learning and artificial intelligence methods for predicting liver toxicity

6. Metaclassifiers and multitask learning for predicting toxicity endpoints with complex mechanism

7. Application of machine learning and artificial intelligence methods in developmental toxicity

8. Application of machine learning and artificial intelligence methods in toxicity assessment of nanoparticles

9. ViNAS-Pro: online nanotoxicity data, modeling, and predictions

10. A geospatial artificial intelligence-based approach for precision air pollution estimation in support of health outcome analysis

11. Application of machine learning methods in water quality modeling

12. Application of machine learning and artificial intelligence methods for predicting antimicrobial resistance

13. Application of machine learning and artificial intelligence methods in food safety assessment

14. From data to decisions: Leveraging machine learning and artificial intelligence methods for human health risk assessment of environmental pollutants

15. Application of machine learning and artificial intelligence methods in toxicity and risk assessment of chemical mixtures

16. Generative artificial intelligence for research translation in environmental toxicology and the ethical considerations

Product details

  • Edition: 1
  • Latest edition
  • Published: October 23, 2025
  • Language: English

About the editors

ZL

Zhoumeng Lin

Dr. Zhoumeng Lin is an Associate Professor in the Department of Environmental and Global Health at College of Public Health and Health Professions at the University of Florida. He is a member of the Center for Environmental and Human Toxicology (CEHT) and the Center for Pharmacometrics and Systems Pharmacology (CPSP). He received a B.Med. in Preventive Medicine from Southern Medical University in China in 2009 and a Ph.D. in Toxicology from the University of Georgia in 2013. He completed his postdoctoral training in Computational Toxicology in the Institute of Computational Comparative Medicine at Kansas State University in 2016. He was an Assistant Professor from 2016 to 2021 and then an Associate Professor from March to May 2021 at Kansas State University, prior to joining the University of Florida as an Associate Professor in May 2021. Dr. Lin’s research is focused on the development and application of computational technologies, especially physiologically based pharmacokinetic (PBPK) modeling, machine learning, and artificial intelligence approaches, to study nanomedicine, food safety, nanoparticle and chemical risk assessment. He is a co-author of more than 100 peer-reviewed manuscripts. He teaches two graduate level courses entitled “Physiologically Based Pharmacokinetic Modeling in Toxicology and Risk Assessment” and “Artificial Intelligence in Toxicology and Environmental Health”.

Affiliations and expertise
Associate Professor, Department of Environmental and Global Health, College of Public Health and Health Professions, University of Florida, Gainesville, USA

WC

Wei-Chun Chou

Dr. Wei-Chun Chou is a Research Assistant Professor of the Department of Environmental and Global Health and a member of the Center for Environmental and Human Toxicology (CEHT) at the University of Florida. He received his PhD in Biomedical Engineering and Environmental Sciences from the National Tsing Hua University, Taiwan in 2013. He completed his postdoctoral training in the Institute of Computational Comparative Medicine at Kansas State University in 2021. His research focused on the development of computational models for prediction of chemical toxicity and its application on human health risk assessments without resorting to animal testing. The goals are accomplished by integrating in vitro high-throughput toxicity screening data, physiologically based pharmacokinetic (PBPK) modeling, machine learning and artificial intelligence to quantitatively describe the relationships between environmental exposure and mechanisms that cause adverse effects in human populations. He has received several awards and honors from the Society of Toxicology (SOT), including the Andersen-Clewell Trainee Award of the Biological Modeling Specialty Section and Best Paper Award of Risk Assessment Specialty Section.

Affiliations and expertise
Research Assistant Professor, Center for Environmental and Human Toxicology, College, University of Florida, Gainesville, USA

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