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Maternal-Fetal and Neonatal Endocrinology

Physiology, Pathophysiology, and Clinical Management

  • 2nd Edition - October 13, 2025
  • Latest edition
  • Editors: Christopher S. Kovács, Cheri L. Deal
  • Language: English

Maternal-Fetal and Neonatal Endocrinology: Physiology, Pathophysiology, and Clinical Management, Second Edition continues to systematically examine the normal and abnormal endocr… Read more

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Description

Maternal-Fetal and Neonatal Endocrinology: Physiology, Pathophysiology, and Clinical Management, Second Edition continues to systematically examine the normal and abnormal endocrinology of the pregnant and lactating female and of the fetus and neonate. This new edition expands coverage of specific disorders and diseases beyond the current endocrinology content on the market making it the go-to reference for translational and clinical research scientists to appreciate the research gaps that require further investigation. It’s comprehensive coverage of pathophysiology, diagnosis, and treatments, will help readers better understand how various diseases present differently in pregnancy and lactation and how to respond to related complications.

Key features

  • Key reference for fellows and residents for rarer endocrine pathologies
  • Integrated presentation of new molecular and genetic causes of endocrine disorders
  • Bridges the experience/knowledge gap of endocrinopathies rarely encountered in pregnancy
  • Thoroughly updated with more emphasis on new technologies, obesity, and transgender medicine
  • Offers new chapter on pineal disorders in the fetus and neonate

Readership

Adult and paediatric endocrinologists, obstetricians/gynecologists, neonatologists, pediatricians, primary care physicians who provide obstetrical care, residents and fellows in the relevant specialties, translational and clinical research scientists, PhD Students

Table of contents

SECTION 1: THE MOTHER
A. Normal endocrine physiology of the mother during conception, pregnancy, and lactation

1. Normal Endocrine Physiology of Hypothalamic Hormones During Ovulation, Pregnancy, and Lactation
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

2. The Pineal Gland and its Function in Pregnancy and Lactation
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

3. Pituitary Physiology During Pregnancy and Lactation
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

4. Thyroid Physiology During Pregnancy, Postpartum, and Lactation
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

5. Physiology of Calcium, Phosphorus, and Bone Metabolism During Pregnancy, Lactation, and Postweaning
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

6. Gestational Glucose Metabolism: Focus on the Role and Mechanisms of Insulin Resistance
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

7. Gut Hormones in Pregnancy and Lactation
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

8. Adrenal Cortex and Medulla Physiology During Pregnancy, Labor, and Puerperium
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

9. Ovarian Function During Pregnancy and Lactation
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

10. The Physiological Roles of the Renin-Angiotensin Aldosterone System and Vasopressin in Human Pregnancy
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

11. Central Role of Adipose Tissue in Pregnancy and Lactation
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

12. Hormonal regulation of the menstrual cycle and ovulation
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

13. Maintenance of Pregnancy and Parturition
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

14. The Onset and Maintenance of Human Lactation and its Endocrine Regulation
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

15. Postpartum Lactational Amenorrhea and Recovery of Reproductive Function and Normal Ovulatory Menstruation
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List
B. Maternal endocrine disorders during conception, pregnancy, and lactation

16. Hypothalamic Disorders During Ovulation, Pregnancy, and Lactation
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

17. Pineal Gland Disorders and Circadian Rhythm Alterations in Pregnancy and Lactation
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

18. Pituitary Disorders During Pregnancy and Lactation
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

19. Thyroid Disorders During Pregnancy, Postpartum, and Lactation
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

20. Thyroid Cancer During Pregnancy and Lactation
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

21. Disorders of Mineral and Bone Metabolism During Pregnancy and Lactation
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

22. Gestational Diabetes and Type 2 Diabetes During Pregnancy
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

23. Type 1 Diabetes: During Preconception, Pregnancy, Postpartum, and Breastfeeding
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

24. Gut and Pancreatic Neuroendocrine Tumors in Pregnancy and Lactation
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

25. Adrenal Pathologies During Pregnancy and Postpartum
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

26. Hypertension in Pregnancy
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

27. Preconception and Pregnancy in Women with Obesity, Postbariatric Surgery, and Polycystic Ovarian Syndrome
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List
C. Transgendered Issues

28. Fertility, Pregnancy, and Chest Feeding in Transgendered Individuals
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

SECTION 2: THE CHILD
D. Normal endocrine development and physiology of the fetus and neonate

29. Endocrinology of Implantation
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

30. Normal Hypothalamic and Pituitary Development and Physiology in the Fetus and Neonate
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

31. The Pineal Gland Development and its Physiology in Fetus and Neonate
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

32. Normal Thyroid Development and Function in the Fetus and Neonate – Sarah Lawrence, Julia Elisabeth von Oettingen and Johnny Deladoëy
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

33. Physiology of Calcium, Phosphorus, and Bone Metabolism During Fetal and Neonatal Development
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

34. Developmental Physiology of Carbohydrate Metabolism and
the Pancreas
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

35. Developmental Origins and Roles of Intestinal Enteroendocrine Hormones
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

36. Development and Function of the Adrenal Cortex and Medulla in the Fetus and Neonate
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

37. Development and Function of the Ovaries and Testes in the Fetus and
Neonate
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

38. Development of Renin-Angiotensin-Aldosterone and Nitric Oxide System in the Fetus
and Neonate
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

39. Origins of Adipose Tissue and Adipose Regulating Hormones
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

40. Fetal and Placental Growth Physiology and Pathophysiology
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

41. Placental Production of Peptide, Steroid, and Lipid Hormones
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List
E. Endocrine disorders affecting the fetus or neonate

42. Hypothalamic and Pituitary Disorders Affecting the Fetus and Neonate
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

43.Pineal Disorders in the Fetus and Neonate
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

44. Fetal and Postnatal Disorders of Thyroid Function
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

45. Disorders of Calcium, Phosphorus, and Bone Metabolism During Fetal and Neonatal Development
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

46. Pathophysiology and Management of Disorders of Carbohydrate Metabolism and Neonatal Diabetes
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

47. Intestinal Enteroendocrine Disorders in the Fetus and Neonate
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

48. Disorders of the Adrenal Cortex in the Fetus and Neonate
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

49. Disorders of Sex Development
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

50.Pathophysiological Roles and Disorders of Renin-Angiotensin-Aldosterone System and Nitric Oxide During Perinatal Periods
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

51. Obesity/Perinatal Origins of Obesity
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

52. Abnormal Fetal Growth
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

53. Small for gestational age babies: management and long term growth and metabolic outcomes
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

54. The effects of maternal obesity on the fetus, neonate, and child
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

55. The effects of maternal diabetes on the fetus, neonate, and child
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List
F. New Diagnostic Technologies and Other Strategies

56. Novel technologies in Prenatal Diagnosis
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

57. Novel Technologies in Postnatal Diagnosis
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

58. Reaching Out: The Value and Challenge of Patient Support Organizations
Introduction
Key Clinical Changes Boxed Summary
Key Demonstrative Figures/Tables
Extensive Reference List

Product details

  • Edition: 2
  • Latest edition
  • Published: October 13, 2025
  • Language: English

About the editors

CK

Christopher S. Kovács

Dr. Kovács is a highly recognized Research Professor of Medicine, Endocrinology, Obstetrics & Gynecology and has received over a dozen national and international awards for excellence in research, including a Gold Medal in Medicine from the Royal College of Physicians and Surgeons of Canada; Young Investigator Award from the Canadian Society of Endocrinology and Metabolism, and Young Investigator Awards from the American Society for Bone and Mineral Research and Advances in Mineral Metabolism. He has served on Editorial Boards of journals, CIHR and NIH grant committees, and as a reviewer for grant agencies in Canada, USA, England, Ireland, and Australia. He was also on the Institute of Medicine / National Academies of Science USA Committee to Review Calcium and Vitamin D. His graduate students have won over 60 international, national, and local awards for excellence in research from various international societies.
Affiliations and expertise
Research Professor, Faculty of Medicine, Endocrinology Health Sciences Centre Memorial University of Newfoundland, Newfoundland, Canada

CD

Cheri L. Deal

Cheri L. Deal, PhD, MD, is a Professor of Endocrinology in the Department of Pediatrics, University of Montreal, and the Chief of the Endocrinology Service at the Ste-Justine Mother-Child University Teaching Hospital in Montreal, Canada. Her training took her to McGill University, University of Montreal, and finally Stanford University for her endocrine research fellowship in placental growth. Past President of both the Canadian Pediatric Endocrine Group and the Canadian Society of Endocrinology and Metabolism, she now chairs the Education Committee of the International Society of Endocrinology. Her awards include the Young Investigator Award from the Pediatric Endocrine Society (previously LWPES), and most recently the Harvey Guyda Educator of the Year Award and the Robert Volpé Service Award from the Canadian Society of Endocrinology and Metabolism. Her major research interest is in the contribution of the growth hormone-insulin-like growth factor (GH-IGF) axis to the regulation of human growth. She has a strong commitment to patient-driven research, and has helped to elucidate the molecular defects associated with a wide range of rare pediatric endocrine disorders as well as participated in clinical studies aimed at ameliorating outcomes in a variety of pediatric endocrine diseases.
Affiliations and expertise
Professor of Endocrinology, Department of Pediatrics, University of Montreal, and the Chief, Endocrinology Service, Ste-Justine Mother-Child University Teaching Hospital, Montreal, Canada

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