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Microbial Biofilms

Role in Human Infectious Diseases

  • 1st Edition - April 10, 2024
  • Latest edition
  • Editors: Mukesh Kumar Yadav, Jae Jun Song, Jorge E. Vidal
  • Language: English

Microbial biofilms are serious problem in medical settings as they are associated with significant mortality and morbidity. Infection related to biofilms not only increases re… Read more

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Description

Microbial biofilms are serious problem in medical settings as they are associated with significant mortality and morbidity. Infection related to biofilms not only increases recovery time, but also escalates the cost of disease management. Biofilms are intrinsically resistant to antibiotics and evade human defense mechanisms. In addition, the close proximity of microbes within biofilms promotes genetic transformation, facilitating the acquisition of antibiotic-resistant genes and leading to an increased prevalence of diseases associated with resistance. Fortunately, with advances in science and technology, novel strategies are being utilized to mitigate the impact of biofilms on human health.

Microbial Biofilms: Role in Human Infectious Diseases focuses on new and emerging concepts in microbial biofilm research. It explores topics such as the mechanisms of biofilm formation, biofilm-induced pathogenesis, biofilm detection and diagnosis, gene exchange within biofilms, strategies to control microbial biofilms, and the burden of biofilm-associated infections. Additionally, the book highlights the various antibiofilm strategies, such as surface coating, signal quenching, novel compounds that can be translated to curb biofilm-associated infections, and the escalation of antimicrobial resistance determinants.

Key features

  • Fulfills the knowledge gap in biofilm study
  • Focuses on new and emerging concepts in microbial biofilm research
  • Highlights the various anti-biofilm strategies
  • Provides concise, thorough and up-to-date information about the important role of microbial biofilms in human diseases

Readership

Graduate students, Post-graduate students, along with researchers and PhD scholars working in the field of biotechnology, clinicians, scientists and industry personnel working on microbial biotechnology and medical microbiology, microbiology and immunology

Table of contents

1. Bacterial Biofilms and infectious disease in human health: a concise review

2. Microbial biofilms: Role of biofilms in recurrent orthopaedic infections

3. Dental biofilms: Application of nanoparticles to combat biofilms

4. Streptococcus biofilms, and their role in human infectious diseases

5. Surface coating: Strategy to prevent bacteria adhesion on medical implants

6. Bacterial biofilm a major challenge in medical indwelling devices

7. Single-species and multi-species biofilms causing infections

8. Effects of environmental factors to promote formation of biofilms by respiratory pathogens

9. Gut Microbiota: Role of biofilms in human health

10. Antimicrobial/antibiotic resistance of biofilms and factors contributing to resistance

11. Cell to cell interaction and cell signalling in biofilms

12. Microbial biofilms and the skin microbiome

13. Synthetic and phyto-compounds to combat microbial biofilms

14. Next generation sequencing: Role in microbial biofilms study

Product details

  • Edition: 1
  • Latest edition
  • Published: April 10, 2024
  • Language: English

About the editors

MY

Mukesh Kumar Yadav

Dr. Mukesh Kumar Yadav is working as Professor at the Department of Microbiology, Central University of Punjab, Bathinda, India. Prof. Yadav has more than 15 years of research experience in medical microbiology, particularly in microbial biofilms and host-microbial interactions. Prof. Yadav has published over 110 research articles, garnering more than 7,000 citations, and has authored five books with Elsevier. He has completed eight major research projects funded by the Indian Council of Medical Research (ICMR), the Department of Biotechnology (DBT), the Department of Science and Technology (DST), and the National Research Foundation (South Korea). Prof. Yadav's research area focuses on host-microbial interactions and microbial biofilms, including pathogenic and commensal bacteria in the gut. Prof. Yadav's lab is working on understanding microbial biofilms and infections caused by the biofilm mode of growth, as well as antimicrobial resistance (AMR), and identifying suitable strategies to combat AMR and drug resistance. Understanding Commensal Bacterial Interaction and Dysbiosis of Gut Microbiota during Various Metabolic Disorders.

Affiliations and expertise
Professor, Department of Microbiology, Central University of Punjab, Bathinda, Punjab, India

JS

Jae Jun Song

Prof. Jae Jun Song is a Professor at Korea University College of medicine Seoul, South Korea. Prof. Song is clinical professional and has more than 15 years of research experience. He has published more than 80 research papers in peer-reviewed journals and has completed many research grants related to microbial biofilms
Affiliations and expertise
Professor, Department of Otorhinolaryngology – Head and Neck Surgery, Korea University College of Medicine, South Korea

JV

Jorge E. Vidal

Dr. Jorge E. Vidal is an Associate Professor in the Department of Cell and Molecular Biology and a member of the Center for Immunology and Microbial Research at the University of Mississippi Medical Center. In his research laboratory, Dr. Vidal studies the molecular mechanisms of bacterial pathogenesis, biofilm formation, and the mechanisms leading to the acquisition of antibiotic resistance. Dr. Vidal has published more than 100 research papers and has received several research grants from the NIH, BMGF, Pfizer, and other agencies.
Affiliations and expertise
Department of Microbiology and Immunology, University of Mississippi Medical Center, Jackson, USA

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