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Elsevier

Molecular Biology of Neurodegenerative Diseases

  • 1st Edition, Volume 107 - April 13, 2012
  • Latest edition
  • Editor: David B. Teplow
  • Language: English

Neurodegenerative diseases result in progressive degeneration and / or death of nerve cells which leads to problems with movement and mental functioning. Examples include Pa… Read more

Description

Neurodegenerative diseases result in progressive degeneration and / or death of nerve cells which leads to problems with movement and mental functioning. Examples include Parkinson’s, Alzheimer’s and Huntington’s disease. Much research is taking place to try to identify ways to prevent or lessen the impact of these diseases.

This volume reviews the latest research and developments in the molecular biology of neurodegenerative diseases.

Key features

  • Contributions from leading authorities
  • Informs and updates on all the latest developments in the field

Readership

Researchers in molecular biology, biochemistry, cell biology and genetics

Table of contents

  1. Neuropathology and imaging

    2. Harry Vinters

  2. Neuropathology and imaging

    3. Thompson, Paul

  3. Age-dependence of neurodegenerative diseases (organismal genetics)

    4. Tanzi, Rudolph

  4. AD

    5. Dominic Walsh

  5. PD

    6. Guo, Ming

  6. PD

    7. Rochet, Chris and

  7. Prion I: Human

    8. Surewicz, Witold

  8. Prion II: Yeast

    9. Tuite, Mick

  9. Cerebral amyloid angiopathy Cerebral amyloid angiopathy

    10. Yamada, Masahito Naiki, Hironobu Tau, and Gloria Lee

  10. Membrane Pores

    11. Kagan, Bruce

  11. Unfolded protein response

  12. ALS

    13. Dokholyan, Nikolay

  13. CAG-repeat diseases

    14. Chris Ross

  14. Mitochondria

Lee Martin

Review quotes

Praise for the series:
"Full of interest not only for the molecular biologist—for whom the numerous references will be invaluable—but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell."—British Medical Journal

Product details

  • Edition: 1
  • Latest edition
  • Volume: 107
  • Published: April 13, 2012
  • Language: English

About the editor

DT

David B. Teplow

David B. Teplow, Ph.D., is a Professor of Neurology, Emeritus, at UCLA and an internationally recognized leader in efforts to understand and treat Alzheimer's disease. Dr. Teplow's group has used a multi-disciplinary approach to determine how neurotoxic peptides, such as the amyloid β-protein (Alzheimer's disease) and α-synuclein (Parkinson’s disease), form neurotoxic structures that kill neurons and to develop the means to block these processes. Dr. Teplow received undergraduate training at UC Berkeley; a Ph.D. from the University of Washington; and was a postdoctoral scholar at Caltech. Before coming to UCLA, Dr. Teplow was a faculty member in the Department of Neurology, Harvard Medical School. Dr. Teplow has published >250 peer-reviewed articles, books and book chapters, and commentaries, in addition to serving on numerous national and international scientific advisory boards. Dr. Teplow was a founding editor of the Journal of Molecular Neuroscience and Current Chemical Biology, He is Editor-in-Chief of the Elsevier serial Progress in Molecular Biology and Translational Science and is Associate Editor-in-Chief of the American Journal of Neurodegenerative Disease.

Affiliations and expertise
Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA

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