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Molecular Biology

  • 2nd Edition - July 10, 2013
  • Latest edition
  • Authors: David P. Clark, Nanette J. Pazdernik
  • Language: English

Molecular Biology, Second Edition, introduces the basic concepts of molecular biology while incorporating primary literature from today’s leading researchers. This new edition r… Read more

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Description

Molecular Biology, Second Edition, introduces the basic concepts of molecular biology while incorporating primary literature from today’s leading researchers. This new edition reflects the massive surge in our understanding of the molecular foundations of genetics, thanks to major scientific revolutions in genetics and computer technology. It explains how living organisms function at a molecular level and how DNA, RNA, and proteins interact to provide the cell with genetic information.

This volume goes far beyond the flowing text, annotation, and hyperlinking available in most ebooks. Unique features include interactive quizzes for enhanced student understanding and self-testing; narrated animations to clarify complex content; and study guides equipped with 62 full-text Cell Press journal articles, all in one downloadable package. Also new to this second edition are updated chapters on genomics and systems biology, proteomics, bacterial genetics, and molecular evolution and RNA. A fully revised art completes the updates made in this ebook.

This book will be of interest to undergraduate students taking a course in Molecular Biology, as well as upper-level students studying Cell Biology, Microbiology, Genetics, Biology, Pharmacology, Biotechnology, Biochemistry and Agriculture.

Key features

  • Winner of a 2013 Texty Award from the Text and Academic Authors Association
  • Includes interactive elements for enhanced student understanding and self-testing; animations to clarify complex content; and study guides equipped with full-text Cell Press journal articles
  • New to second edition: updated chapters on genomics and systems biology; proteomics; bacterial genetics; and molecular evolution and RNA
  • Fully revised art

Readership

Undergraduate students taking a course in Molecular Biology; upper-level students studying Cell Biology, Microbiology, Genetics, Biology, Pharmacology, Biotechnology, Biochemistry and Agriculture

Table of contents

Unit 1: Basic Chemical and Biological Principles

Ch1 Cells and Organisms

Ch2 Basic Genetics

Ch3 DNA, RNA, and Protein

Ch4 Genes, Genomes, and DNA

Ch5 Manipulation of Nucleic Acids

Unit 2: The Genome

Ch6 Polymerase Chain Reaction

Ch7 Cloning Genes for Analysis

Ch8 DNA Sequencing

Ch9 Genomics & Systems Biology

Unit 3: The Central Dogma of Molecular Biology

Ch10 Cell Division and DNA Replication

Ch11 Transcription of Genes

Ch12 Processing of RNA

Ch13 Protein Synthesis

Ch14 Protein Structure & Function

Ch15 Proteomics: Global Analysis of Proteins

Unit 4: Regulating Gene Expression

Ch16 Regulation of Transcription in Prokaryotes

Ch17 Regulation of Transcription in Eukaryotes

Ch18 Regulation at RNA Level

Ch19 Analysis of Gene Expression (Transcriptome)

Unit 5: Subcellular Life Forms

Ch20 Plasmids

Ch21 Viruses

Ch22 Mobile DNA

Unit 6: Changing the DNA Blueprint

Ch23 Mutations and Repair

Ch24 Recombination

Ch25 Bacterial Genetics

Ch26 Molecular Evolution

Product details

  • Edition: 2
  • Latest edition
  • Published: July 10, 2013
  • Language: English

About the authors

DC

David P. Clark

David P. Clark did his graduate work on bacterial antibiotic resistance to earn his Ph.D. from Bristol University, England. He later crossed the Atlantic to work as a postdoctoral researcher at Yale University and then the University of Illinois. Dr Clark recently retired from teaching Molecular Biology and Bacterial Physiology at Southern Illinois University which he joined in 1981. His research into the Regulation of Alcohol Fermentation in E. coli was funded by the U.S. Department of Energy, from 1982 till 2007. In 1991 he received a Royal Society Guest Research Fellowship to work at Sheffield University, England while on sabbatical leave.

Affiliations and expertise
Southern Illinois University

NP

Nanette J. Pazdernik

Nanette J. Pazdernik has devoted her career to the understanding of molecular biology and biotechnology, and then disseminating that knowledge by writing and teaching. She is a co-author of Biotechnology, 2nd edition and Molecular Biology, 3rd edition, with Dr. David P. Clark and Dr. Michelle McGehee. Both the second and third edition of Molecular Biology won a Texty award from the Textbook and Academic Authors Association. She has taught courses in General Biology, Genetics, as well as Anatomy and Physiology at Southwestern Illinois College, McKendree University, and Harris-Stowe University. She received her BA in Biology from Lawrence University in Appleton, Wisconsin, and her PhD in Molecular, Cellular, Developmental Biology and Genetics from the University of Minnesota. Her doctoral thesis studied protein structure-function relationships. Following her degrees, she investigated the signal transduction pathways that control apoptosis and immunity at Indiana University School of Medicine. In a second post-doctoral position, she studied the various molecules that maintain the stem cell niche in the Department of Genetics at Washington University School of Medicine in St. Louis, MO. Currently, Dr. Pazdernik works in the biotech industry as a scientific writer.

Affiliations and expertise
Integrated DNA Technologies