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Molecular Pharmaceutics and Nano Drug Delivery

Fundamentals and Challenges

  • 1st Edition - October 17, 2023
  • Latest edition
  • Editors: Umesh Gupta, Amit K. Goyal
  • Language: English

Molecular Pharmaceutics and Nano Drug Delivery: Fundamentals and Challenges provides a thorough resource for both beginners and established scientists, bringing fundament… Read more

Description

Molecular Pharmaceutics and Nano Drug Delivery: Fundamentals and Challenges provides a thorough resource for both beginners and established scientists, bringing fundamental knowledge about key challenges of these carriers down to the molecular level. The book satisfies the need of availability of literature at single platform with the detailed knowledge to understand crucial aspects, such as regulatory, clinical, toxicological and the formulation requirements of these carriers. This is a valuable resource for graduates, pharmaceutical researchers and anyone working on aspects of pharmaceutics, molecular pharmaceutics and nano-drug/gene delivery.

So called ‘novel drug delivery systems’ are numerous, with each having different approaches to their production, characterization and evaluation. The proper understanding of these dosage forms, as well as their critical attributes such as toxicity and regulatory requirements are aspects which researchers should know before they begin working on these carriers. This book provides this critical information.

Key features

  • Provides a conceptual understanding of Molecular Pharmaceutics and drug/gene delivery systems of biological origin
  • Presents a detailed description and discussion on nanotechnological carriers, from basics to advances, including gene delivery and protein-oriented delivery
  • Includes regulatory and toxicological requirements for novel drug delivery systems

Readership

Graduates, pharmaceutical researchers and anyone working on aspects of pharmaceutics, molecular pharmaceutics and nano-drug/gene delivery; Industry researchers, developing novel formulations using critical aspects of the pharmaceutics at molecular level

Table of contents

1. Protein and enzyme-based nanoformulations
Biswakanth Kar, Deepak Pradhan, Prativa Biswasroy, Jitu Haldar, Tushar Kanti Rajwar, Vineet Kumar Rai, Goutam Ghosh and Goutam Rath

2. Vaccines and sera
Garima Sahu, Priyanka Kumari and Amit K. Goyal

3. Aptamers and antisense oligonucleotide-based delivery
Fatemeh Yazdian and Amin Janghorbani

4. Monoclonal antibodies: recent development in drug delivery
Sumel Ashique, Prathap Madeswara Guptha, Jovita Kanoujia, Ashish Garg, Afzal Hussain, S. Mohana Lakshmi and Neeraj Mishra

5. Hormonal delivery systems
Shivani Rai Paliwal, Kunjbihari Sulakhiya, Pramod Kumar, Sabyasachi Maiti and Rishi Paliwal

6. Vesicular drug delivery systems: a novel approach in current nanomedicine
Elisabetta Mazzotta, Martina Romeo and Rita Muzzalupo

7. Polymeric micelles in drug delivery and targeting
Anchal Pathak, Teeja Suthar, Gautami Nirbhavane and Keerti Jain

8. Physicochemical characterization of drug delivery systems based on nanomaterials
Viviane Lucia Beraldo-de-Arau´jo, Victo´ ria Soares Soeiro, Marcelo Van Vliet Lima, Juliana Souza Ribeiro Costa and Laura de Oliveira-Nascimento

9. Inorganic and metal-based nanoparticles
Gajanan Paul, Ujjwal Gupta, Hinal Shah, Farhan M

10. Dendrimers: promises and challenges in drug delivery
Aadil Sk Khatik, Satish Kurdhane, Sanya Batheja and Umesh Gupta

11. Development of advanced diagnostic platform for detection of infectious diseases
Deepshikha Shahdeo, Drishya Prakashan and Sonu Gandhi

12. Fundamentals of a targeted drug delivery system
Akash Chaurasiya, Sonali Singh, Kanan Panchal, Rishi Paliwal and Akanksha Malaiya

13. Assessment of nanotoxicology through in vitro techniques and image-based assays
Fernanda Garcia-Fossa, Tuanny Leite Almeida, Rafaella Mascarelli Pereira, Thaı´s Moraes-Lacerda, Mariana Rodrigues Da Silva, Laura de Oliveira-Nascimento and Marcelo Bispo de Jesus

14. Gene therapy: advocacies, perspectives, and ethical provocations
Rajeev Taliyan, Rajesh Sukhija, Ameya Kothekar, Ansit Mishra, Priyamvada Nair and Shaifali Gurjar

Product details

  • Edition: 1
  • Latest edition
  • Published: October 17, 2023
  • Language: English

About the editors

UG

Umesh Gupta

Dr. Umesh Gupta, currently working as Assistant Professor at Department of Pharmacy, Central University of Rajasthan, India, did his bachelor's, master's and doctorate degree in Pharmaceutical Sciences from Dr. H. S. Gour University, India under the mentorship of Prof. NK Jain. He has recently been awarded for “DAAD Research Stays for Academics and Scientists” at Leibniz-institut fur Polymerforschung Dresden, Germany. He has the past experience of Research Scientist at Ranbaxy Research Laboratories, India and Post-Doctoral Research Associate at South Dakota State University, USA. HE is also recipient of Young Scientist Award by Department of Science and Technology, Government of India as well as Ranbaxy Science Scholar Award 2008 by Ranbaxy Research Laboratories, India. He has been awarded more than 3-4 times the overseas travel award by different funding agencies of Indian government to share and present his research at international platform in countries like Germany, USA and Singapore etc. He has more than ten years of research and academic experience. The area of research is mainly focused on dendrimer mediated drug delivery, solubilization and targeting. His laboratory equally focuses on effective brain delivery through nanotechnological carriers such as polymeric micelles, nanoparticles and dendrimers. He has more than 48 publications and seven book chapters to his credit with total citations of more than 2300 (h index of 23 as per Google Scholar).
Affiliations and expertise
Assistant Professor, Department fo Pharmacy, Central University of Rajasthan, India

AG

Amit K. Goyal

Dr. Amit Kumar Goyal is Professor and Head, Department of Pharmacy, Central University of Rajasthan, India. He has more than 15 years of teaching and research experience at postgraduate and graduate level and worked as a Professor & Head, Department of Pharmaceutics, at ISF College of Pharmacy, Punjab, India. Subsequently, he joined as an Associate Professor at Gujarat Forensic Science University, Gandhinagar and after that as a Scientist at National Institute of Animal Biotechnology, Hyderabad. Dr. Goyal has completed his M. Pharm. and Ph. D. from Department of Pharmaceutical Sciences, Dr. H. S. Gour University, Sagar (M.P.). Dr. Goyal is the leading scientist in the field of cutting age platform technology (Nanotechnology) for site specific targeted delivery of drugs and bio-actives. Dr. Goyal is expert in formulation development and delivery of drugs, vaccines and herbal bio-actives. He is working towards the common goals of exploring new ways of delivering herbal/bio-actives ingredient with the use of nanotechnology.
Affiliations and expertise
Professor and Head, Department of Pharmacy, Central University of Rajasthan, India

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