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Multifunctional Nanocarriers

  • 1st Edition - August 20, 2022
  • Latest edition
  • Editors: Neelesh Kumar Mehra, Saurabh Srivastava, Jitender Madan, Pankaj Kumar Singh
  • Language: English

Multifunctional Nanocarriers provides information on the concept, theory and application of multifunctional nanocarriers. The book covers current research, beginning with produc… Read more

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Description

Multifunctional Nanocarriers provides information on the concept, theory and application of multifunctional nanocarriers. The book covers current research, beginning with product strategy, targeted drug delivery, and advanced drug delivery approaches, along with numerous multifunctional nanocarriers and their regulatory considerations for product development. The book covers targeting, receptor mediated targeting, and recent advancements using multifunctional nanocarriers and their regulatory aspects. This is an important reference source for materials scientists and engineers who want to learn more about how multifunctional nanocarriers are applied in a range of biomedical applications.

Key features

  • Explains the fundamentals, concepts, theory and application of multifunctional nanocarriers, with advanced content and applications for a range of biomedical applications
  • Covers production and manufacturing processes for multifunctional nanocarriers for biomedical applications
  • Assesses major challenges in applying multifunctional nanocarriers on an industrial scale

Readership

Materials scientists and engineers

Table of contents

Section A: Targeted Drug Delivery and Targeting

1. Nanotechnology: Advanced Drug Targeting Concepts, Fundamentals, and Strategies

2. Advanced Multifunctional Nanomaterials – An Introduction

3. Receptors Based Drug Targeting and Targeted Drug Delivery

4. Quality by Design (QbD) Approach in Drug Delivery Systems and Drug Targeting

5. Mitochondrial Targeting Strategies and Applications

6. Mucosal Vaccine Delivery and Targeting and Drug Delivery Strategies

7. Ophthalmic Drug Delivery; Opportunities, Major Challenges, and Application

8. Nano-immuno-adjuvants-based Immunotherapy in the Treatment of Cancer

9. Brain Targeting Drug Delivery Systems for the Management of Brain Disorders: Molecular targets and nano-technological strategies

10. Drug Delivery Through Nails: Concept, Theory and Application

Section B: Multifunctional Nano-carriers in Drug Delivery and Targeting

11. Dendrimers-specific Drug Delivery and Drug Targeting

12. Nanoparticles-mediated Drug Targeting Strategies

13. Carbon Nanotubes in Controlled and Targeted Drug Delivery

14. Liposomal Formulation: Current Landscape and Industrial Applicability

15. Self-emulsifying Drug Delivery and Targeting

16. Pro-drug Strategy in Drug Targeting & Delivery

17. Graphenes and Fullerenes as Drug Delivery Systems

18. Quantum Dots (QDs) in Biomedical Applications

19. Drug-conjugate Strategies in Drug Delivery

20. Colloidosomes in Drug Delivery and Targeting

21. Polymeric Micelles, Role, Implication in Drug Delivery

22. Nano emulsion-based Delivery and Targeting

23. Solid Lipid Nanoparticles as Drug Carriers

24. Cochleates as Nanoparticles Drug Carriers in Drug Delivery

25. Super-paramagnetic Iron Oxide Nanoparticles (SPION) in Drug Delivery

26. Role of Pharmacokinetics/Pharmacodynamics Modeling in Drug Targeting

27. Nano-toxicology: Toxicity and Safety Issue of Nanomaterials

28. Exosomes-mediated Drug Delivery

29. Current Status of FDA Approved Market Products

Product details

  • Edition: 1
  • Latest edition
  • Published: August 25, 2022
  • Language: English

About the editors

NM

Neelesh Kumar Mehra

Neelesh Kumar Mehra is an Assistant Professor of Pharmaceutics in the Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Hyderabad, India. He has authored more than 140 peer-reviewed publications in high-repute international journals, and has contributed to over 50 book chapters. He holds 4 granted patents and has 5 patent applications filed on manufacturing processes and compositions to improve therapeutic efficacy for drug delivery. He has supervised 5 PhD students and 36 MS students, and is currently guiding 10 PhD and 7 MS students on their dissertations and research projects. His research focuses on the design, development, and evaluation of ophthalmic nanoemulsions, liposomes, lipid-polymer nanoparticles, carbon nanoparticles, and chitosan/PLGA-lipid nanoparticles for drug and biomolecule delivery in biomedical applications.
Affiliations and expertise
Assistant Professor of Pharmaceutics, Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, India

SS

Saurabh Srivastava

Saurabh Srivastava is an Associate Professor of Pharmaceutics, at the National Institute of Pharmaceutical Education and Research, Hyderabad, India. His research interests include the development and optimization of industrially viable, feasible and scalable differentiated formulations, for the purpose of bioavailability enhancement, food effect minimization, repurposing/new indication, synergism for FDCs, and dose/dosing frequency reduction.
Affiliations and expertise
Associate Professor of Pharmeceutics, National Institute of Pharmaceutical Education and Research, Hyderabad, India

JM

Jitender Madan

Dr. Jitender Madan is Associate Professor and Head of the Department of Pharmaceutics at NIPER Hyderabad, a leading researcher and educator in pharmaceutical sciences. His research centers on self-assembled supramolecular systems—liposomes, niosomes, cyclodextrins, nano- and microparticles, and solid-lipid nanoparticles—and leverages FDA-approved biomaterials with lipids and polymers to develop innovative dosage forms that improve bioavailability, stability, safety, and patient compliance. He has mentored numerous doctoral and postgraduate scholars and led industry collaborations and government-funded projects. Notable products include cycloencapsulated andrographolide for immune support and a veterinary spray for bovine mastitis. He has authored a robust body of peer-reviewed papers and book chapters, holds several patents, and has edited nanotechnology-focused volumes. A recognized educator and researcher, he actively contributes as a peer reviewer and advances pharmaceutical science and education through programs like SRIP.

Whilst a wide range of applications are being taken up, the special emphasis is given to augment the aqueous solubility and bioavailability of lipophilic drugs.
Affiliations and expertise
Associate Professor, National Institute of Pharmaceutical Education and Research, Hyderabad, Telangana, India

PS

Pankaj Kumar Singh

Dr. Pankaj Kumar Singh, Ph.D., is an Assistant Professor in the Department of Pharmaceutics at the National Institute of Pharmaceutical Education and Research-Hyderabad (NIPER-Hyderabad), India. He earned his Doctorate in Pharmaceutics from CSIR-Central Drug Research Institute, Lucknow. Dr. Singh is actively involved in various scientific and socially impactful projects funded by prestigious organizations, including TSCOST-DBT, CCRUM, DST, ICMR, and the Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, Government of India.
Affiliations and expertise
Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, Telangana, India

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