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Elsevier

Novel Therapeutic Approaches Targeting Oxidative Stress

  • 1st Edition - February 18, 2022
  • Latest edition
  • Editors: Pawan Kumar Maurya, Imteyaz Qamar
  • Language: English

Novel Therapeutic Approaches Targeting Oxidative Stress investigates the role of oxidative stress in disease and explores the latest methods and approaches to targeting oxidative… Read more

Description

Novel Therapeutic Approaches Targeting Oxidative Stress investigates the role of oxidative stress in disease and explores the latest methods and approaches to targeting oxidative stress for treatment and diagnosis. The book begins with an introduction to oxidative stress and its significance. Subsequent sections cover biochemical methods for detecting free radicals and novel therapeutic approaches for targeting oxidative stress in a number of different diseases. This includes age-related illnesses, neuropsychiatric disorders such as schizophrenia and bipolar disorder, and neurodegenerative diseases like Alzheimer’s and Parkinson’s disease. Novel approaches for targeting oxidative stress in cancer and cardiovascular diseases are also explored.

The book then moves on to discuss advances in drug delivery systems and detecting oxidative stress biomarkers using biosensors. It concludes with case studies that illustrate the targeting of oxidative stress and future perspectives.

Key features

  • Explores oxidative stress in a variety of diseases, including neurological disorders, cardiovascular diseases, age-related diseases, and cancer
  • Covers a range of therapeutic approaches to target oxidative stress
  • Includes chapters on the application of novel drug delivery systems and diagnostic biosensors to oxidative stress
  • Features case studies illustrating the targeting of oxidative stress

Readership

Researchers and clinicians working in the area of oxidative stress, such as molecular biologists, biochemists, cell biologists, and pharmacologists. PhD and postgraduate students in biomedical sciences and those working with oxidative stress and related fields

Table of contents

1. Introduction

2. Oxidative stress and its biological significance

2.1 Reactive Oxygen Species (ROS)

2.2 Oxidative stress

2.3 Antioxidants

3. Biochemical approaches/methods in detection of free radicals

3.1 In-vitro methods

3.2 In-vivo methods

3.3 Other biochemical methods

4. Novel therapeutic approaches targeting oxidative stress in aging

5. Novel therapeutic approaches targeting oxidative stress in neuropsychiatric disorders

5.1 Schizophrenia

5.2 Bipolar disorder

5.3 Major Depressive Disease

5.4 Other neuropsychiatric disorders

6. Novel therapeutic approaches targeting oxidative stress in neurodegenerative diseases

6.1 Alzheimer’s disease

6.2 Parkinson’s diseases

7. Novel therapeutic approaches targeting oxidative stress in cancer

8. Novel therapeutic approaches targeting oxidative stress in cardiovascular diseases

9. Advancements in novel drug delivery systems: Providing a challenge and threat to oxidative stress in various diseases

10. Detection of oxidative stress biomarkers using biosensors

11. Case studies targeting oxidative stress

12. Future perspectives

13. Bibliography

14. Glossary

Product details

  • Edition: 1
  • Latest edition
  • Published: February 18, 2022
  • Language: English

About the editors

PM

Pawan Kumar Maurya

Dr. Pawan Kumar Maurya is a biochemist and Professor in the Department of Biochemistry at the Central University of Haryana, where he also serves as Dean of Academic Affairs. He earned his MSc and PhD in Biochemistry from the University of Allahabad. His research spans oxidative stress, aging, nanomedicine, and clinical biochemistry. He has completed postdoctoral training at several institutions in Asia and Brazil. Dr. Maurya has been honored with national and international awards for his work. He is active in professional societies including the Association of Gerontology India, the Society of Neurochemistry India, and Indian Biochemists’ and Microbiologists’ associations. His scholarly output includes books, book chapters, and numerous research articles. He contributes to technical and organizing committees for national and international conferences. A dedicated educator, he specializes in biochemical diagnostics, nanomedicine, and clinical biochemistry, with a track record of editorial work with major publishers.
Affiliations and expertise
Central University of Haryana, Mahendergarh (Haryana), India

IQ

Imteyaz Qamar

Dr. Imteyaz Qamar is working as an assistant professor at School of biotechnology, Gautam Buddha University, Greater Noida, India. His area on interest is Stress biology, and Cancer Genetics He earned his Ph.D. in Molecular Endocrinology from Chonnam National University, South Korea with an emphasis on gene regulation and physiological function of an androgen receptor corepressor-19kD using mice model. He has written various manuscripts, grants, progress reports, pre-IND protocols, animal protocols and published in well reputed international journals. He has also received various awards such as Brain Korea-21 Best Research presenter award 2007, Bharath Vikas award 2016, Young Scientist Award 2017 & 2019, STE meritorious award 2019 etc. He serves as a member of editorial boards of various peer reviewed journals. He is also a member of the endocrinology society, United States of America (USA).
Affiliations and expertise
Assistant Professor, School of Biotechnology, Gautam Buddha University, Greater Noida, Gautam Buddha Nagar, Uttar Pradesh, India

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