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On Oxygen

From Air to Tissues

  • 1st Edition - November 25, 2024
  • Latest edition
  • Editors: Michael Joyner, Jerome Dempsey
  • Language: English

On Oxygen: From Air to Tissues, the latest release in the Fundamentals of Physiology series, provides a fundamental overview of the entire oxygen pathway, sharing key mechanistic… Read more

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Description

On Oxygen: From Air to Tissues, the latest release in the Fundamentals of Physiology series, provides a fundamental overview of the entire oxygen pathway, sharing key mechanistic insights into the alternating conductive and diffusive steps of O2 transport. The book describes specific aspects along each stage of the oxygen route through the body, from the transfer of air to the alveoli, through the lungs, to the ultimate fate of O2 in the mitochondria. Additionally, the effect of specific disease states, aging, and developmental aspects are considered.

This book, published in association with the International Union of Physiological Sciences, acts is a valuable introduction to the full biological journey of oxygen, and is a beneficial guide for students and researchers in physiology, sport science, pulmonology, and related fields.

Key features

  • Offers a comprehensive, integrated overview of oxygen delivery systems from air to cell and its impact on physiological function
  • Covers fundamental aspects of each stage of oxygenation, providing a reductionist approach to complex topics
  • Explores physiological responses in the human body at rest and during exercise
  • Includes case studies considering various mammals, terrestrial vertebrates, and aquatic animals in discussion of how body size influences key elements of the O2 transport chain

Readership

Researchers in the area of physiology, sport science, medicine, pulmonology, cell biology and related biomedical fields, Students in physiology, pulmonology, medicine, cell biology and related areas

Table of contents

1. The roadmap

2. The air

3. The lung

4. The lung/blood interface

5. Getting oxygen through the lung

6. Getting oxygen from lung to tissues

7. From microcirculation to mitochondria

8. After O2 is used, CO2’s return trip to the air

9. Scaling and animal size

10. Comparative solutions to unique problems

Review quotes

"...a unique approach to cover the respiratory system using the stress of exercise to engagingly teach the fundamentals to readers.... provide[s] an integrative, rather than reductionist, approach to the physiology of respiration using exercise as a practical and relatable stressor to engage readers,... [and] establishes that oxidative metabolism is the dominant mechanism for providing ATP for animals and that the physical active state is and should be the healthy norm.... The book’s use and interpretation of original literature is impressive, and this data-driven approach contributes to the accuracy of what is known and unknown in a way that more opinion-based pieces cannot do as convincingly.... A couple of the data figures were very helpful; readers will want to go back to these original articles and think about them more or use them for their own teaching.... [It] does an extraordinary job in pulling off its approach for readers with some preexisting knowledge. There are currently no other books in this class for trainees,... I recommend it widely." Review by Thad Wilson, PhD (University of Kentucky College of Medicine), ©Doody's Review Service, 2025.

Product details

  • Edition: 1
  • Latest edition
  • Published: November 27, 2024
  • Language: English

About the editors

MJ

Michael Joyner

Michael Joyner, M.D., is a physician-researcher and leading expert on human performance and exercise physiology. He is currently a consultant in the Department of Anesthesiology and Perioperative Medicine and Department of Physiology and Biomedical Engineering at the Mayo Clinic, United States. Using humans as his model system, he has made major contributions to understanding muscle and skin blood flow, blood pressure regulation, and human athletic performance. Dr. Joyner has been a consultant to the National Institutes of Health (NIH) and NASA and has held leadership positions with prestigious scientific journals. His research lab at Mayo Clinic has been continuously funded by the NIH since 1993, and Mayo Clinic named him a Distinguished Investigator in 2010.
Affiliations and expertise
Consultant, Department of Anesthesiology and Perioperative Medicine, and Department of Physiology and Biomedical EngineeringMayo Clinic, Rochester, Minnesota, USA

JD

Jerome Dempsey

Jerome A. Dempsey is the Director of the John Rankin Laboratory of Pulmonary Medicine at the University of Wisconsin, United States. His research interests are concerned with the regulation of breathing in various physiologic states in un-anesthetized humans and animals. He is involved with the supervision of trainees and instructor in respiratory / exercise / sleep physiology for medical students, undergraduates and graduate students. Dr. Dempsey is the recipient of a number of awards including the Bayliss-Starling Prize Lecture awared by the UK Physiologic Society in 2012 and the 2013 Bodil M. Schmidt-Nielsen Distinguished Mentor and Scientist Award from the American Physiological Society. He is the former Editor-in-Chief of the Journal of Applied Physiology and currently is the CrossTalk Editor for the Journal of Physiology.
Affiliations and expertise
Professor Emeritus and Director, Population Health Sciences, John Rankin Laboratory of Pulmonary Medicine, University of Wisconsin, Madison, Wisconsin, USA

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