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Pharmaceutical Applications of Dendrimers

  • 1st Edition - November 15, 2019
  • Latest edition
  • Editors: Abhay Singh Chauhan, Hitesh Kulhari
  • Language: English

Pharmaceutical Applications of Dendrimers explores the applications of dendrimers in the solubilization of hydrophobic active ingredients, drug delivery, gene delivery, imaging,… Read more

Description

Pharmaceutical Applications of Dendrimers explores the applications of dendrimers in the solubilization of hydrophobic active ingredients, drug delivery, gene delivery, imaging, diagnosis and photodynamic therapy. The book discusses the diagnostic applications of dendrimers, including their use as MRI contrast agents and in the imaging of diseased areas. In addition, the anti-inflammatory, antimicrobial and antiviral properties of PPI and PAMAM are also covered, along with a discussion on photosensitizers, such as rose Bengal and protoporphyrin IX that have been delivered using PAMAM and PPI dendrimers for the treatment of cancer.

This book is an important research reference for those who want to learn more about the development of dendrimer-based solutions for drug delivery.

Key features

  • Explores the role of dendrimers in the design of dendritic nanoplatforms for targeted drug and gene delivery systems
  • Discusses the potential of dendrimers in preformulation and formulation development
  • Addresses both clinical and regulatory challenges in the development of dendrimer-based formulations

Readership

Materials scientists and biomedical researchers who are looking to learn more about how dendrimers can be used to create more efficient drug delivery solutions

Table of contents

1. Dendrimers: Introduction, types and properties

2. Dendrimers as solubility enhancer or excipient

3. Dendrimers as therapeutic agent/drug

4. Biocompatibility and toxicity of dendrimers

5. Dendrimers as drug delivery carrier

6. Dendrimers for the delivery of biological drugs

7. Pharmacokinetic considerations in design of dendrimer-based nanomedicines

8. Design of dendrimer-based prodrugs

9. Stimuli-responsive dendrimers in drug delivery

10. Dendrimer-based targeted drug delivery

11. Dendrimers in photodynamic therapy

12. Diagnostic applications of dendrimer based nanovectors

13. Overview of current clinical status of dendrimer-based formulations

Product details

  • Edition: 1
  • Latest edition
  • Published: November 15, 2019
  • Language: English

About the editors

AC

Abhay Singh Chauhan

Abhay Singh Chauhan is Associate Professor, School of Pharmacy at the Medical College of Wisconsin, USA. He was previously Director of Pharmaceutical Nanotechnology at Concordia University, USA. His research is in the area of nanopharmaceuticals.
Affiliations and expertise
College of Wisconsin, USA

HK

Hitesh Kulhari

Dr. Hitesh Kulhari is an Assistant Professor at the School of Nano Sciences, Central University of Gujarat, India. He completed his PhD at RMIT University, Australia, from 2011 to 2015. Prior to that, he earned his Master of Pharmacy at the Bundelkhand University, India, in 2008.

Dr. Kulhari's remarkable contributions have been recognized with prestigious awards, including the Prof CNR Rao Research Excellence Award in Material Science, the INSPIRE Faculty Award, and the Early Career Research Award. His research interests include nanomedicines and nanobiomaterials.

Affiliations and expertise
Assistant Professor, Central University of Gujarat, India

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