Phytonutrients and Neurological Disorders
Therapeutic and Toxicological Aspects
- 1st Edition - July 11, 2023
- Latest edition
- Editors: Haroon Khan, Michael Aschner, Hamed Mirzaei
- Language: English
Phytonutrients and Neurological Disorders: Therapeutic and Toxicological Aspects provides and assesses the latest research and developments surrounding the use of phyton… Read more
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Description
Description
Phytonutrients and Neurological Disorders: Therapeutic and Toxicological Aspects provides and assesses the latest research and developments surrounding the use of phytonutrients for the treatment of neurological disorders. The volume analyzes advances in phytonutrient isolation, characterization and therapeutic applications, giving particular emphasis to mechanisms and safety profiles. The book takes toxicological considerations into account, including adverse drug reactions, toxicokinetics and toxicodynamics. Sections cover bioactive compound classes and biosynthesis pathways, general considerations, including quality control, standardization, and technology, and toxicology. This title is a comprehensive work on the latest research in phytonutrients and neurological disorders that will be useful to researchers and medical practitioners.
Key features
Key features
- Presents a comprehensive resource on phytonutrients and their relationship to neurological disorders
- Analyzes the isolation, characterization and mechanisms of phytonutrients in neurology
- Focuses on various signaling pathways followed by phytonutrients in neuroprotection
- Gives the latest thinking on quality control parameters and specifications for phytonutrient study
- Considers the toxicology of phytonutrients, including adverse drug reactions, toxicokinetics and toxicodynamics
Readership
Readership
Natural product researchers, nutritionists, medical practitioners, pharmacologists and pharmacognosists, food chemists, food scientists, phytochemists, medical chemistry researchers, Medical students and graduate students in pharmacology, pharmaceutical science, and related fields
Table of contents
Table of contents
Part A, Section 1: Bioactive compound classes and biosynthesis pathway
1. Current therapies for neurological disorders and their limitations
2. Biosynthesis of phytonutrients
3. Neuroprotective effects of flavonoids
4. Neuroprotective effects of glycosides
5. Neuroprotective effects of terpenoids
6. Neuroprotective effects of alkaloids
7. Neuroprotective effects of saponins
8. Neuroprotective effects of steroids
9. Neuroprotective effects of essential oils
10. Neuroprotective effects of phytonutrients at gene levels
Part A Section 2: General considerations
11. Latest development in quality control parameters/specification in phytonutrients studies
12. Phytonutrients standardization for effective therapeutic outcomes
13. Phytonutrients and technological development in formulations
Part B Sections: Toxicological considerations in phytonutrients
a. Adverse drug reactions
b. Toxicokinetics
c. Toxicodynamics
1. Current therapies for neurological disorders and their limitations
2. Biosynthesis of phytonutrients
3. Neuroprotective effects of flavonoids
4. Neuroprotective effects of glycosides
5. Neuroprotective effects of terpenoids
6. Neuroprotective effects of alkaloids
7. Neuroprotective effects of saponins
8. Neuroprotective effects of steroids
9. Neuroprotective effects of essential oils
10. Neuroprotective effects of phytonutrients at gene levels
Part A Section 2: General considerations
11. Latest development in quality control parameters/specification in phytonutrients studies
12. Phytonutrients standardization for effective therapeutic outcomes
13. Phytonutrients and technological development in formulations
Part B Sections: Toxicological considerations in phytonutrients
a. Adverse drug reactions
b. Toxicokinetics
c. Toxicodynamics
Review quotes
Review quotes
"...provides a good introduction to plant-based nutraceuticals in neurological disorders [and] helps the reader understand the many different plant derivatives, including polyphenols, flavones, flavanols, cathechins, and anthrocyanins. [A]ims to discuss the latest research into the role of phytonutraceuticals in neurological illnesses. [A] helpful resource for neurologists as often patients are interested in incorporating nutraceuticals in their treatment plans...[A] decent reference for phytonutraceuticals in neurological disorders. It can be a helpful resource for neurologists who are interested in advising patients about non-pharmacological plant-derived supplements."—©Doody’s Review Service, 2024, Shin Beh, MD, FAAN, FAHS (University of Texas Southwestern Medical Center at Dallas)
Product details
Product details
- Edition: 1
- Latest edition
- Published: July 11, 2023
- Language: English
About the editors
About the editors
HK
Haroon Khan
Prof. Dr. Haroon Khan has obtained the degree of B. Pharm (1999), M. Phil (2005), and PhD (2011) from the Department of Pharmacy, University of Peshawar. He started his career as a lecturer from the Gandhara College of Pharmacy, Gandhara University, Peshawar and currently, Professor of Pharmacy at the Department of Pharmacy, Abdul Wali Khan University Mardan, Pakistan. He has more than seventeen years of experience in pharmacy teaching, research and professional expertise in various fields of pharmaceutical sciences. Dr. Khan has 162 publications, including research, review, and editorial in various national and international reputable journals with considerable impact factor while several others are submitted or in the process of submission. His research focus is phytomedicines including phytopharmacological and phytochemical investigations of extracts/isolated compounds in collaboration with numerous national and international research groups.
The scientific contribution of Dr. Khan has been acknowledged by the Pakistan Council for Science and Pakistan Council for Science and Technology (PCST) and awarded Research Productivity four times 2011-2014. He has also published three books with LAMBERT Academic publishers, Germany and four chapters. He is also the editorial board member of various international journals. Additionally, he is supervising many post-graduate scholars in various research projects.
Affiliations and expertise
Professor, Department of Pharmacy, Abdul Wali Khan University, PakistanMA
Michael Aschner
Dr. Michael Aschner is currently the Harold and Muriel Block Chair in Molecular Pharmacology at Albert Einstein College of Medicine where he is also a Professor in the Departments of Molecular Pharmacology, Neuroscience, and Pediatrics. He is a leading expert in neurotoxicology and neurodevelopmental and neurodegenerative diseases. In addition to serving as a past president of the Society of Toxicology (2022-23), he served on numerous toxicology panels (U.S. EPA and CDC), been an expert reviewer for multiple federal agencies in the US and abroad, and is a member of the Neurotoxicology and Alcohol study section (NIH). He is a past recipient of the prestigious Society of Toxicology Merit Award (2010) and the Distinguished Neurotoxicologist Award (2020). He is a co-editor of the Elsevier series, Advancements in Neurotoxicology in addition to edited other Elsevier titles. He has published numerous articles and has served as an associate editor for multiple high impact factor journals.
Affiliations and expertise
Professor, Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, USAHM
Hamed Mirzaei
Hamed Mirzaei is a Professor at the Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Iran.
Affiliations and expertise
Professor, Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, IranView book on ScienceDirect
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