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Elsevier

Quality Control and Evaluation of Herbal Drugs

Evaluating Natural Products and Traditional Medicine

  • 1st Edition - May 29, 2019
  • Latest edition
  • Author: Pulok K. Mukherjee
  • Language: English

Quality Control and Evaluation of Herbal Drugs brings together current thinking and practices for evaluation of natural products and traditional medicines. The use of herbal me… Read more

Description

Quality Control and Evaluation of Herbal Drugs brings together current thinking and practices for evaluation of natural products and traditional medicines. The use of herbal medicine in therapeutics is on the rise in both developed and developing countries and this book facilitates the necessary development of quality standards for these medicines.This book elucidates on various challenges and opportunities for quality evaluation of herbal drugs with several integrated approaches including metabolomics, chemoprofiling, marker analysis, stability testing, good practices for manufacturing, clinical aspects, Ethnopharmacology and Ethnomedicine inspired drug development.

Written by Prof. Pulok K Mukherjee, a leader in this field; the book highlights on various methods, techniques and approaches for evaluating the purity, quality, safety and efficacy of herbal drugs. Particular attention is paid to methods that assess these drugs’ activity, the compounds responsible and their underlying mechanisms of action. The book describes the quality control parameters followed in India and other countries, including Japan, China, Bangladesh, and other Asian countries, as well as the regulatory profiles of the European Union and North America. This book will be useful in bio-prospecting of natural products and traditional medicine-inspired drug discovery and development.

Key features

  • Provides new information on the research and development of natural remedies - essential reading on the study and use of natural resources for preventative or healing purposes
  • Brings together current thinking and practices in quality control and standardization of herbal drugs highlighting several integrated approaches for metabolomics, chemo-profiling and marker analysis
  • Aids in developing knowledge of various techniques including macroscopy, microscopy, HPTLC, HPLC, LC-MS/MS, GC-MS etc. with the development of integrated methods for evaluation of botanicals used in traditional medicine
  • Assessment of herbal drugs through bio-analytical techniques, bioassay guided isolation, enzyme inhibition, pharmacological, microbiological, antiviral assays and safety related quality issues
  • References global organizations, such as the WHO, USFDA, CDSCO, AYUSH, TCM and others to serve as a comprehensive document for enforcement agencies, NGOs and regulatory authorities

Readership

those involved in the fields of herbal medicine, traditional medicine, pharmaceutical sciences and natural product research. Researchers in the herbal drug industry and academicians studying relevant areas of plant sciences, analytical chemistry, medicinal chemistry, phyto-chemistry, alternative medicine, pharmacognosy, natural products and related fields will be benefited. Graduate and post graduate students and researchers in these areas but also will be useful to the technocrats in the industries and the legislators to know more about the methodologies developed for quality evaluation of herbal drugs

Table of contents

1. Traditional systems of medicines and harmonization2. Ethnopharmacology and ethnomedicines-inspired drug development3. Quality evaluation of herbal medicines: Challenges and opportunities4. Qualitative analysis for evaluation of herbal drugs5. Morphological and microscopical evaluations6. Extraction and other downstream procedures for evaluation of herbal drugs7. Bioactive phyto-components and their analysis8. Thin layer chromatography for evaluation of herbal drugs9. High performance thin layer chromatography (HPTLC) for analysis of herbal drugs10. High performance liquid chromatography for analysis of herbal drugs11. LC-MS: A rapid technique for understanding the plant metabolomic analysis12. Chemo-profiling and marker analysis for quality evaluation of herbal drugs13. Bioassay guided isolation and evaluation of herbal drugs14. Enzyme inhibition studies for evaluation of herbal drugs15. Evaluation of herbal drugs for antimicrobial and parasiticidal effects16. Antiviral evaluation of herbal drugs17. Plant metabolomics and quality evaluation of herbal drugs18. Safety related quality issues for development of herbal drugs19. Quality assurance of herbal drugs and stability testing20. Phytopharmaceuitcals, nutraceuticals and their evaluation21. Regulatory harmonization and good quality practices for development of herbal medicine

Product details

  • Edition: 1
  • Latest edition
  • Published: May 29, 2019
  • Language: English

About the author

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Pulok K. Mukherjee

Pulok Kumar Mukherjee is currently working as a professor at Jadavpur University, Kolkata, India, where his research centers on bioprospecting of natural products within translational chemical biology. He previously served as Director of the Institute of Bioresources and Sustainable Development (IBSD) and as Director (additional charge) of the Institute of Life Sciences, Bhubaneswar, under the Department of Biotechnology, Government of India. His research integrates traditional knowledge with modern scientific tools, emphasizing evidence-based validation of medicinal plants for drug development, metabolomics, quality assurance, and regulatory aspects of herbal medicine. He holds several patents and has authored/edited multiple books and chapters with various publishers. He has published more than 290 peer-reviewed articles and is ranked among the top 2% scientists worldwide in a Stanford University study. He has played a key role in shaping policies and guidelines on traditional medicine research, serving on expert committees for the World Health Organization, the Department of Biotechnology, and the Indian Council of Medical Research, among others. A recipient of numerous awards and fellowships, Prof. Mukherjee has built impactful collaborations across academia, industry, and government, advancing translational research and sustainable development in natural products.
Affiliations and expertise
Professor, Department of Pharmaceutical Technology, School of Natural Product Studies, Jadavpur University, Kolkata, West Bengal, India

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