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Statistical Bioinformatics with R

Statistical Bioinformatics provides a balanced treatment of statistical theory in the context of bioinformatics applications. Designed for a one or two semester senior undergrad… Read more

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Description

Statistical Bioinformatics provides a balanced treatment of statistical theory in the context of bioinformatics applications.

Designed for a one or two semester senior undergraduate or graduate bioinformatics course, the text takes a broad view of the subject – not just gene expression and sequence analysis, but a careful balance of statistical theory in the context of bioinformatics applications.

The inclusion of R & SAS code as well as the development of advanced methodology such as Bayesian and Markov models provides students with the important foundation needed to conduct bioinformatics.

Key features

  • Integrates biological, statistical and computational concepts
  • Inclusion of R & SAS code
  • Provides coverage of complex statistical methods in context with applications in bioinformatics
  • Exercises and examples aid teaching and learning presented at the right level
  • Bayesian methods and the modern multiple testing principles in one convenient book

Readership

Senior undergraduate and graduate level students taking a one or two semester course in bioinformatics

Table of contents

1. Introduction

2. Genomics

3. Probability and Statistical Theory

4. Special Distributions, Properties and Applications

5. Statistical Inference and Applications6. Nonparametric Statistics

7. Bayesian Statistics

8. Markov Chain, Monte Carlo

9. Analysis of Variance

10. Design of Experiments

11. Multiple Testing of Hypotheses

Review quotes

"Students and biologists who want to specialize in the fast-paced field of bioinformatics should read this book. Mathur brings together a comprehensive and very practical view of the field. He combines sufficient mathematical proofs with hints and suggestions, and provides many real examples taken directly from the genetics, proteomics, and molecular biology fields…Many other bioinformatics topics—for example, clustering algorithms, specialized R packages, or the challenges of analyzing mass-spectrometry data—are only alluded to and not covered fully in the book. However, in its entirety, this is a very useful, clearly written introduction to statistical bioinformatics with R. It contains many real examples, and would be a help to those starting out in the field."—Computing Reviews.com

Product details

About the author

SM

Sunil K. Mathur

Dr. Sunil Mathur is a distinguished professor of Biostatistics at Weill Cornell Medical College and a full member of both the Houston Methodist Academic Institute and the Houston Methodist Neal Cancer Center. He serves as the Director of Biostatistics and Co-Director of the Biostatistics and Bioinformatics Shared Resources at the Houston Methodist Neal Cancer Center and the Houston Methodist Research Institute. Dr. Mathur has previously held several key positions: he was a Professor and Chair of the Department of Mathematics and Statistics and Assistant to the Dean for Research Development at Texas A&M University-Corpus Christi; a Professor and Director of the Research Support Center at Augusta University’s Medical College of Georgia; an Associate Professor at the School of Public Health, University of Memphis; and an Associate Professor and Director of the Statistical Consulting Center at the University of Mississippi. Dr. Mathur is the Editor-in-Chief of the American Journal of Statistical Science and Applications and serves as an Associate Editor for multiple journals, including the Journal of Applied Statistics and the International Journal of Statistics and Systems. He is also on the editorial boards of the Global Journal of Medicine and Public Health and the Austin Journal of Public Health and Epidemiology. He has successfully secured over $50 million in external grant funding from various sources, including the NIH, DOD, NSF, DOE, and the US Army as PI/Co-PI/Co-I. Dr. Mathur reviews grant proposals for the National Science Foundation, DOD, and other agencies, and he is a member of the Data Safety and Monitoring Board for NIH grants. His contributions have been recognized with numerous awards, such as the Digital Innovator of the Year Award and the Graduate Resource and Opportunity Workspace Friends Award. Dr. Mathur is currently the President of the San Antonio Chapter of the American Statistical Association and a former President of the Texas Association of Academic Administrators in the Mathematical Sciences (T3AMS). He is an elected member of the International Statistical Institute and is a member of the American Statistical Association and the International Indian Statistical Association, USA.
Affiliations and expertise
Director, Statistical Computing and Consulting CenterUniversity of Mississippi, Oxford, USA