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Books in Immunology

Elsevier's Immunology collection equips researchers with valuable insights to address the complexities of the immune system and its role in health and disease, offering original research, insightful analysis, and current theory on diagnosing, managing, and advancing treatments for allergies, asthma, and immunologic disorders.

  • Inflammation and Cancer

    Mechanisms, Diagnosis, and Therapeutic Strategies
    • 1st Edition
    • Anoop Kumar + 4 more
    • English
    Inflammation and Cancer: Mechanisms, Diagnosis, and Therapeutic Strategies delves into the intricate relationship between inflammation and cancer, a crucial area of contemporary biomedical research. Sections provide an overview of inflammation's role in cancer, discussing molecular connections and signaling pathways. Chapters explore inflammatory pathways in various cancers, including breast, oral, lung, prostate, skin, and gastrointestinal cancers. The book also covers tumorigenesis, metastasis, preventive strategies, inflammatory biomarkers for cancer diagnosis, and innovative therapeutic designs. Final chapters focus on the dual role of platelets, targeting tumor-associated macrophages, novel treatment approaches, and recent advances in the field.This title offers substantial benefits to researchers, clinicians, and healthcare professionals by providing a thorough understanding of the cellular and molecular pathways linking inflammation and cancer, aiding in the development of effective anti-cancer immunotherapies. By highlighting the latest research and potential therapeutic strategies, this book serves as an essential resource for anyone dedicated to combating cancer through innovative and informed immunotherapeutic approaches.

  • Inflammatory Arthritis Beyond the Joints

    Comorbidities and other Manifestations
    • 1st Edition
    • Volume 18
    • Fabiola Atzeni + 1 more
    • English
    Inflammatory Arthritis Beyond the Joints, Volume 18 in Elsevier’s Handbook for Systemic Autoimmune Diseases series, provides an extensive review of the most recent research on various comorbidities and EAMs associated with inflammatory arthritis. The book emphasizes early detection, which is crucial for improving patient quality of life and survivability outcomes, as many adults with inflammatory arthritis also suffer from other chronic conditions. The book's chapters cover comorbidities and EAMs in both early and late disease stages.They delve into the mechanisms behind the development of these conditions and examine the impact of new treatment strategies specific to inflammatory arthritis and related diseases, including cardiovascular disease, metabolic syndrome, metabolic bone disease, infection, neoplasia, respiratory disease, gastrointestinal disorders, kidney issues, mental health conditions, and neurological diseases. This book serves as a valuable reference for researchers and clinicians focused on inflammatory arthritis and its associated conditions.

  • Immunological Aspects of Preterm Birth

    • 1st Edition
    • Volume 4
    • Irina Burd MD
    • English
    Immunological Aspects of Preterm Birth, a volume in the Reproductive Immunology book series, bridges reproductiveimmunolo... of preterm birth to subtypes, phenotypes, and bedside prevention and treatment. This book reviews therole of the different immune mechanisms during pregnancy leading to preterm birth and fetal programming effects thatare connected to maternal immune activation. This book also discusses immune cells and their products, cytokines andchemokines, as central for the success of the pregnancy, from the process of implantation to parturition and the effects ofthe changes on fetal programming.While our knowledge on the role of immune cells and the inflammatory process in preterm birth has grown exponentiallyin the last 10 years, connecting basic science to clinical science and development of new therapeutics has not progressedas rapidly. This book assists researchers in understanding the basic immunologic mechanisms and inflammatory processesassociated with preterm birth and fills an urgent need for the development of therapeutics in this space.

  • Advancing Early Diagnosis in Chronic Diseases

    Tools, Techniques, and Technologies
    • 1st Edition
    • Sachchida Nand Rai + 2 more
    • English
    Advancing Early Diagnosis in Chronic Diseases: Tools, Techniques, and Technologies explores the transformative potential of early detection strategies and technologies in reshaping chronic disease outcomes. Addressing the urgent need for innovative approaches to managing conditions such as cardiovascular diseases, diabetes, cancer, neurodegenerative disorders, and pediatric chronic conditions, this book underscores the importance of timely interventions to reduce disease burden and improve quality of life. Chronic diseases are leading causes of mortality and morbidity worldwide, making early diagnosis and intervention critical. The book provides a comprehensive overview of cutting-edge tools, including predictive biomarkers, artificial intelligence, genomic and proteomic screening, wearable health devices, digital twins, and point-of-care testing. Readers will gain insights into how these advancements revolutionize early diagnosis and personalized treatment. Written by experts from interdisciplinary fields, it bridges the gap between scientific discovery and clinical application, addressing challenges such as knowledge gaps, integration barriers, and accessibility of diagnostic innovations. The book covers a broad spectrum of chronic conditions, including metabolic, inflammatory, respiratory, renal, hepatic, and neurodegenerative diseases, with added focus on pediatric patients and early detection in childhood disorders. “Advancing Early Diagnosis in Chronic Diseases: Tools, Techniques, and Technologies” is an invaluable resource for healthcare professionals, researchers, and policymakers. It offers strategies for implementing scalable and ethical diagnostic solutions in both resource-rich and resource-limited settings. By consolidating emerging technologies and practical applications, this book empowers its readers to transition from reactive to proactive care, ultimately improving patient outcomes and transforming healthcare systems worldwide.

  • Two Sides of Nanovaccines and Nanomedicines in Cancer Treatments

    • 1st Edition
    • Tuan Anh Nguyen + 2 more
    • English
    Two Sides of Nanovaccines and Nanomedicines in Cancer Treatments provides a balanced exploration of the dual roles of nanotechnologies in oncology. Structured in four parts, the book begins with foundational knowledge of nanovaccines and nanomedicines, detailing their applications in cancer care and highlighting their precision in targeting cancer cells while reducing systemic toxicity. Importantly, the book addresses potential drawbacks, discussing side effects and safety concerns associated with these innovations. The final section emphasizes ethical, regulatory, and safety challenges, underscoring the need for careful oversight as nanotechnologies advance.For the academic audience, this book serves as a vital resource, offering insights that equip researchers and healthcare professionals to make informed decisions regarding clinical applications. Its focus on both benefits and risks, alongside forward-looking perspectives, ensures that readers are well-prepared for future developments in the field of nanomedicine and cancer therapy.

  • Lateral Flow Assays for Rapid Point-of-care Testing

    Recent Advances, Emerging Trends, and Future Direction
    • 1st Edition
    • Seema Nara + 2 more
    • English
    The emergence and re-emergence of new infectious diseases places emphasis on the need for greater investment in rapid healthcare diagnostic solutions. As a result, lateral flow immunoassay technology is quickly evolving with new inventions. Lateral Flow Assay for Rapid Point-of-Care Testing covers today’s most significant advancements, emerging trends, and future directions linked with this technology. The book begins with a review of the format, flow, and design of old-generation lateral flow assays and the challenges impeding performance before moving into innovation in materials for rapid test strips, advances in manipulating sample flow, and the latest developments in molecular imprinting and bioconjugation techniques. Subsequent sections cover various biorecognition elements and review signal amplification as well as quantification trends. Final chapters delve into recent applications for infectious diseases detection, monitoring antibiotic resistance, multiplex detection of analytes, as well as future directions leading to the next generation of healthcare. Academicians, researchers, industrialists, and device manufacturers linked to the development of rapid and affordable point-of-care immunodiagnostics will find value in this resource.

  • Inmunología

    • 10th Edition
    • David Male + 2 more
    • Spanish
    Nueva edición de uno de los textos de referencia en inmunología de nuestro portfolio en el que se abordan de forma equilibrada e integrada los conceptos pertenecientes a la inmunología básica y clínica. La estructura general de esta edición de Inmunología es la misma que la de la novena edición, Las secciones 1 y 2 describen el funcionamiento del sistema inmunitario. La sección 3 se ocupa de las respuestas inmunitarias contra los microorganismos patógenos (la función principal del sistema inmunitario), y las secciones 4 a 6 abordan aspectos de inmunología clínica, como las enfermedades autoinmunitarias, la inmunodeficiencia, los trasplantes, la inmunología tumoral y la hipersensibilidad. Todos los capítulos se han actualizado por completo e incluyen numerosos diagramas nuevos. Especial atención merecen los Caps. 17,18,20 y 22 por su profunda actualización en temas relativos a las nuevas vacunas de mRNA, inmunización pasiva, autoinmunidad, nuevos anticuerpos y nuevas terapias celulares y los nuevos descubrimientos a raíz de la epidemia de Covid. Las secciones de razonamiento crítico que siguen a cada capítulo requieren la comprensión del material presentado y de las implicaciones en un entorno de laboratorio o clínico, y sirven como base para el debate en el aula. Otro importante instrumento pedagógico son los resúmenes que recogen los puntos clave de cada capítulo, así como los numerosos esquemas, diagramas y figuras. La nueva edición ofrece contenido adicional online en español a través de la plataforma e-book+. Incluye apartados, tablas y figuras adicionales, así como una colección de 15 videos.

  • Endotoxin in Critical Illness

    • 1st Edition
    • John Kellum + 1 more
    • English
    Endotoxin in Critical Illness intricately explores the theme of endotoxin and sepsis through the lenses of basic, clinical, and translational science. This work consolidates and synthesizes novel clinical insights and groundbreaking scientific discoveries into one comprehensive resource on endotoxic septic shock and sheds light on cutting-edge approaches in treatment. Beginning with a historical journey, the book traces the evolution of understanding from ancient concepts to modern molecular insights. It covers the physiological aspects of endotoxin sensitivity, tolerance, and human response variation. The crucial role of the gut microbiome in critical illness serves as a translational link between foundational science and clinical implications, and the complex language of bacterial communication is introduced, merging basic science with potential translational applications. In the clinical arena, chapters cover the critical role of endotoxin in septic shock, trauma, and its relevance in COVID-19, providing a translational bridge between laboratory findings and real-world clinical scenarios. The historical context of anti-endotoxin drug development is revisited, emphasizing the translational challenges faced in bridging basic science discoveries to clinical applications. The discussion on quantifying endotoxin concentration as well as the exploration of therapeutic rationale and clinical experiences with endotoxin removal therapy serve as a culmination of basic understanding translated into practical applications. The book concludes by contemplating the complexity of sepsis and acknowledging the challenges in achieving personalized medicine and underscoring the dynamic nature of the translational journey. In essence, this comprehensive exploration provides clinicians, researchers, and scientists with a holistic understanding of endotoxin and sepsis and potential advancements in patient care.

  • Myasthenia Gravis

    Disease, Diagnosis and Management
    • 1st Edition
    • Bhupendra G. Prajapati + 2 more
    • English
    Myasthenia Gravis: Disease, Diagnosis and Management is a comprehensive resource that explores recent advancements in diagnosing and treating Myasthenia Gravis, a rare autoimmune disease affecting the neuromuscular junction. With contributions from global experts, this book addresses the increasing prevalence of Myasthenia Gravis, reflecting the latest in diagnostic techniques and novel therapies such as complement inhibitors and FcRn antagonists. It aims to support healthcare professionals in delivering optimal care through evidence-based insights and patient-centered approaches. The book is divided into several chapters, beginning with an overview of the pathogenesis and immunoregulatory defects in Myasthenia Gravis. Subsequent chapters cover diagnostic methods, non-immunosuppressiv... treatments, and biological therapies targeting the immune system. Key topics include the role of intravenous immunoglobulin (IVIg) and plasma exchange (PLEX) in severe exacerbations, thymectomy, molecular mechanisms, and the potential of hematopoietic stem cell transplants. The book also delves into precision medicine, AI applications, clinical trial considerations, and novel therapeutics like anti-FcRn antibodies. Management strategies for ocular Myasthenia Gravis, and a holistic view of living with the disease are also discussed. Myasthenia Gravis: Disease, Diagnosis and Management is invaluable for healthcare providers, physicians, immunologists, ophthalmologists, rheumatologists, physical therapists, pharmacists, and translators. It offers a modern guide to understanding and managing Myasthenia Gravis, integrating clinical expertise with the latest research to improve patient outcomes.

  • Advances in Cancer Research

    • 1st Edition
    • Volume 168
    • English
    Advances in Cancer Research, Volume 168 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Plasticity in cell adhesion during cancer progression, AEG-1 on Cancer Drug Resistance: From Molecular Insights to Therapeutic Challenges, Multimodal AI to differentiate tumor progression from treatment effect in glioblastoma, The Role of Epigenetic Modifications in Mediating Cancer Health Disparities, In search of a targetable immune profile for acute myeloid leukemia, Notch signaling in tumorigenesis and maintenance of cancer stem cells, and much more.

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