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Books in Immunology

Elsevier's Immunology collection equips researchers with valuable insights to address the complexities of the immune system and its role in health and disease, offering original research, insightful analysis, and current theory on diagnosing, managing, and advancing treatments for allergies, asthma, and immunologic disorders.

  • Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation

    Models in Discovery and Translation
    • 1st Edition
    • Gerard Socie + 1 more
    • English
    Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation provides clinical and scientific researchers with a deep understanding of the current research in this field and the implications for translational practice. By providing an overview of the immune biology of HSCT, an explanation of immune rejection, and detail on antigens and their role in HSCT success, this book embraces biologists and clinicians who need a broad view of the deeply complex processes involved. It then moves on to discuss the immunobiology mechanisms that influence graft-versus-host disease (GVHD), graft-versus-leukemi... (GVL) effect, and transplantation success. Using illustrative figures, highlighting key issues, describing recent successes and discussing unanswered questions, this book sums up the current state of HSCT to enhance the prospects for the future. Allogeneic HSCT is a medical procedure in which a patient receives blood-forming stem cells from a genetically similar but not identical donor. This procedure is commonly performed for people with diseases of the blood, bone marrow, or certain cancers, but it remains risky with many possible complications. As such, experimental practice is reserved for preclinical animal models including the mouse and dog. These animal models have been essential in developing transplant protocols, including preclinical testing of conditioning regimens, treatment of GVHD, and understanding the pathology of GVHD as well as the immunological mechanisms of GVHD and GVL effect. However, recent research has revealed significant species differences between humans and animal models that must be considered when relating animal model studies to clinical allogeneic HSCT scenarios.

  • Aerobiology

    • 1st Edition
    • I Silver
    • English
    Aerobiology documents the proceedings of the Third International Symposium held at the University of Sussex, England, in September 1969. The book is organized into three chapters that correspond to the three sessions held during the symposium. These three sessions dealt with themes of airborne infections in closed and segregated environments; the value and use of germ-free environments; and physiological and genetic factors in host resistance. Examples of the contributions during these sessions included studies on the transmission of meningococci among Army recruits; the transfer and acquisition of micro-organisms between and by patients nursed in a uni-directionally ventilated environment and those in an open ward; and the association between blood group status and susceptibility to certain virus infections. The symposium also included seminars that focused on the following themes: intramural spread of infection; laboratory safety; the immunological aspects of pathogenesis; vaccines and vaccination methods; microbial survival in air; rapid diagnosis; techniques in aerobiology; and the ways in which airborne particles cause infection.

  • Immunoassay Automation

    A Practical Guide
    • 1st Edition
    • Daniel W. Chan
    • English
    Immunoassay Automation: A Practical Guide describes automation of immunoassay from the practical viewpoint of the clinical laboratory. General introduction and evaluation sections demonstrate principles and practice. A comprehensive selection of available systems are detailed by experts, with a view towards popularity, technical advances, and operational efficiency. This laboratory guide is essential for practitioners in clinical chemistry laboratories, and will have lasting value in the evolution of automated systems.

  • The Plasma Proteins

    Structure, Function, and Genetic Control
    • 2nd Edition
    • Frank W Putnam
    • English
    The Plasma Proteins: Structure, Function, and Genetic Control, Second Edition, Volume I is a systematic account of the structure, function, and genetic control of plasma proteins. Clinical relevance is introduced in terms of principles, with emphasis on human proteins. Animal proteins are also used as examples in some cases. Comprised of nine chapters, this volume begins with a historical background on plasma proteins, along with their nomenclature, characterization, and genetic markers. The primary structure and three-dimensional conformation of plasma proteins are also considered. The discussion then turns to the chemical, physical, and biological properties of various plasma proteins such as serum albumin, lipoproteins, and immunoglobulins. Subsequent chapters deal with protease inhibitors in plasma; purification, physical properties, chemical composition, and molecular structure of transferrin; biosynthesis and metabolism of serum lipoproteins; and physical, chemical, and functional properties of the proteins of the complement system. The final chapter is devoted to ?2-microglobulin, with particular reference to its purification and physical properties; chemical composition and structure; physiological function, biosynthesis, and catabolism; and presence and function in cell membranes. This monograph will be of interest to molecular biologists and biochemists.

  • Handbook of Mucosal Immunology

    • 1st Edition
    • English
    Researchers have recently made tremendous progress in the area of mucosal immunology, greatly increasing our understanding of the common mucosal immune system, mucosal infections, and oral immunization. However, thisresearch has not previously been made available in a single work. In its large 81/2"x 11"format, Handbook of Mucosal Immunology covers the entire spectrum of mucosal immunity and is organized in two main sections to present the basic biology of the common mucosal immune system and the immune responses of the mucosae.The first section provides an introduction and historical perspective of the mucosal immune system and includes comprehensive discussion of the development and physiology of mucosal defense. It discusses such topics as the structure and function of themucosal epithelium, characteristics of mucosal-associated lymphoid tissue (MALT), Peyers patches, and concepts of mucosal vaccines. The second section focuses on the secretory immune system with special reference to mucosal diseases in the digestive (GALT), respiratory (BALT), and genitourinary tracts. This information is especially important in light of the current interest in the mechanisms, transmission, and prevention of infectious diseases such as AIDS, hepatitis, and tuberculosis.Virtual... all chapters have been authored by the original investigators responsible for key observations on which current concepts are based. This handbook will be an invaluable resource for a diverse group of both researchers and practicing clinicians.Molecular biologists, immunologists, veterinarians, public health workers, physicians in specialties from pediatrics to pulmonology, and graduate students of mucosal immunology will all find this handbook the most complete work on the subject.

  • Molecular Biology of the Fission Yeast

    • 1st Edition
    • English
    This highly researched yeast, which represents a system used by cell biologists, geneticists and molecular biologists, has been given only minimal coverage in the literature. Its properties make it an excellent organism for DNA and related biotechnology reseach. This book, which is the first attempt to collate existing information in one source, will be an invaluable aid to those initiating projects with this organism.

  • Handbook of B and T Lymphocytes

    • 1st Edition
    • English
    To compile this up-to-date handbook, Dr. Charles Snow of the University of Kentucky Medical Center has assembled works by a premier group of active investigators who meet the needs of todays researchers. The handbookprovides a broad overview of the historical and current research in B- and T-cell biology, and presents the latest developments in this fast-breaking field to all professionals concerned with the humoral immune response of the body.

  • Immunotherapy with Intravenous Immunoglobulins

    • 1st Edition
    • Paul Imbach
    • English
    The use of intravenous human antibodies in the treatment of primary immunodeficiencies is well recognized. However, it is now evident that they also have therapeutic potential for a wide range of other clinical disorders. This book describes the use of human antibodies in the management of secondary (virus-induced) immunodeficiencies, neonatal and perinatal infections, and autoimmunity. Insight into their mechanism of action is also provided.

  • Immunochemistry LabFax

    • 1st Edition
    • English
    LABFAX volumes are purpose-designed data reference books for practicing scientists. Each book presents key information for a major subject in one place and so saves hours of searching. The authors and editors of each LABFAX volume have searched the original literature for the accurate data which they know the specialist needs.Immunochemistr... Labfax is a detailed compendium of essential information - on plasma proteins, immunoglobulin properties and purification, antibody production, labeling and derivatization, plus data on techniques such as ELISA, blotting, and immunolocalization - needed constantly by researchers in any area of immunology and related disciplines.

  • Avian Immunology

    • 2nd Edition
    • Bernd Kaspers + 1 more
    • English
    The second edition of Avian Immunology provides an up-to-date overview of the current knowledge of avian immunology. From the ontogeny of the avian immune system to practical application in vaccinology, the book encompasses all aspects of innate and adaptive immunity in chickens. In addition, chapters are devoted to the immunology of other commercially important species such as turkeys and ducks, and to ecoimmunology summarizing the knowledge of immune responses in free-living birds often in relation to reproductive success. The book contains a detailed description of the avian innate immune system, encompassing the mucosal, enteric, respiratory and reproductive systems. The diseases and disorders it covers include immunodepressive diseases and immune evasion, autoimmune diseases, and tumors of the immune system. Practical aspects of vaccination are examined as well. Extensive appendices summarize resources for scientists including cell lines, inbred chicken lines, cytokines, chemokines, and monoclonal antibodies. The world-wide importance of poultry protein for the human diet, as well as the threat of avian influenza pandemics like H5N1 and heavy reliance on vaccination to protect commercial flocks makes this book a vital resource. This book provides crucial information not only for poultry health professionals and avian biologists, but also for comparative and veterinary immunologists, graduate students and veterinary students with an interest in avian immunology.

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