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Books in Pharmaceutical sciences

Elsevier's Pharmaceutical Sciences collection helps pharmaceutical scientists striving to optimize drug design and improve healthcare outcomes by offering comprehensive coverage of every aspect of drug development, integrating disciplines like organic chemistry, biology, and biotechnology. Focused on safety, efficacy, and formulation design, it includes specialized fields such as Clinical Pharmacology and Translational Research, providing valuable insights into the latest advancements in drug discovery.

  • Advances in Tablet Manufacturing Technologies

    • 1st Edition
    • Honey Goel + 2 more
    • English
    Advances in Tablet Manufacturing Technologies consolidates cutting-edge information on the latest technologies in tablet design and manufacturing, addressing the pressing need for innovation in an increasingly complex global market. The book is structured to provide a thorough understanding of tablet technology, beginning with foundational concepts and progressing through specialized topics. Key sections explore the historical context of tablet development, the significance of pharmaceutical excipients, preformulation aspects, and the physics of tablet compression. Subsequent chapters explore advanced topics, including coated tablets, modified-release formulations, organ-specific tablets, and state-of-the-art innovations like 3D printed tablets.Each chapter is enriched with practical examples and case studies, ensuring that readers can apply theoretical knowledge to real-world scenarios. With contributions from a diverse group of national and international experts, this book is an invaluable asset for scientists in academia and industry alike. It elucidates preformulation parameters, outlines regulatory frameworks, and discusses recent advances in excipient technology and in-process testing equipment.

  • Protein-Based Nanoparticles in Drug Delivery

    • 1st Edition
    • Prashant Kesharwani
    • English
    Protein-based Nanoparticles in Drug Delivery is a comprehensive book aimed at pharmaceutical scientists and researchers both in academia and corporate environments focused on nanotechnology drug delivery and pharmaceutical-relat... disciplines. The book covers the design and characterization of various protein nanoparticles, sheds light on the power of an endogenous substance as a drug delivery system, and highlights the possible future trends in the use of protein-based drug delivery. It covers in-depth novel applications of protein-based drug delivery from fundamental to most current use cases. The book comprises three parts. Part one is devoted to the foundations of protein-based drug delivery, including nanocarriers development, drug encapsulation, targetability, and in vivo properties. Part two explores the applications of protein-based nanoparticles in drug delivery, covering topics such as protein nanoparticles in cancer therapy, genetic material delivery, and nanocarriers based on milk protein, silk, and gliadin. Part three addresses recent advances and regulatory aspects of protein-based nanoparticles in drug delivery, including clinical translation, challenges, biological toxicity, and environmental hazards associated with protein-based nanoparticles. Protein-based Nanoparticles in Drug Delivery provides a complete journey of protein-based drug delivery, offers an in-depth understanding of the design and characterization of various protein nanoparticles, and highlights possible future trends in this field. Pharmaceutical scientists will benefit from the novel applications of protein-based nanoparticles drug delivery approaches in the biological field. Nanotechnologists, biologists, chemists, physicists, engineers, and clinicians will also benefit from the foundational content provided as a basis to support communication and tackle the multidisciplinary challenges associated with research in this exciting field.

  • Developing Solid Oral Dosage Forms

    Pharmaceutical Theory and Practice
    • 3rd Edition
    • Yihong Qiu + 4 more
    • English
    Developing Solid Oral Dosage Forms: Pharmaceutical Theory and Practice, Third Edition is a comprehensive and up-to-date guide for professionals and academics engaged in all aspects of oral dosage form development, from discovery support through commercial manufacturing. This new edition features 13 new or rewritten chapters, along with significant updates to existing content, reflecting the latest advancements in the field, including new theories, scientific findings, approaches, techniques, modeling, and the emerging opportunities offered by AI.This book consists of 44 chapters covering in-depth principles of physical pharmacy, biopharmaceutics, and industrial pharmacy, and their applications throughout the R&D process and commercial production of oral dosage forms. New chapters address topics such as absorption evaluation of oral dosage forms, formulation principles, and applications based on supersaturation, patient-centric product design, product design through the 505(b)(2) NDA pathway, design of experiments (DoE), process modeling, 3D printing, and machine learning applications in commercial manufacturing. Existing chapters have been updated or completely rewritten to provide advanced information and include practical case studies. Important topics such as amorphous solid dispersions, modified-release delivery, manufacturing technologies, modeling and simulation, fundamentals of dissolution and bioequivalence, IVIVC, biowaivers, regulatory frameworks, and many others are covered.The new edition of this book is an indispensable resource for industry professionals, academic institutions, and regulatory bodies seeking to stay current with advances in solid dosage form development and manufacturing. It offers a thorough understanding of fundamental principles and techniques, along with practical guidance on applying these concepts to real-world challenges.

  • AI Powered Drug delivery to Neuro and Cardiovascular Systems

    Perspectives and Future Challenges
    • 1st Edition
    • Chandra P. Sharma + 2 more
    • English
    AI-Powered Drug Delivery to Neuro and Cardiovascular Systems: Perspectives and Future Challenges is a definitive reference exploring the transformative influence of Artificial Intelligence (AI) in neuro and cardiovascular drug delivery. This book integrates cutting-edge research to explain how AI is poised to reshape clinical protocols, therapeutic strategies, and regulatory standards. By examining advancements in robotics and intelligent systems, it demonstrates how AI enhances precision, personalization, and efficiency in drug delivery for heart and neurological conditions, providing readers with a thorough understanding of these innovations and their potential to revolutionize healthcare practices.The book delves into AI-driven drug design and testing for cardiovascular diseases and explores the application of AI in cardiac drug delivery vehicles. It discusses bioengineered heart and vessel therapeutics, redox homeostasis, and targeted drug replenishment in cardiac matrix remodeling. Additionally, it addresses mitochondrial drug retention, AI-assisted gene therapy for neurodegenerative disorders, and the role of AI in optimizing heart health. The text highlights smart systems for managing cerebrovascular accidents and neuromodulation with pharmacotherapy. Finally, it covers translational challenges, future directions, and the significance of AI-driven prediction models and robotic delivery mechanisms.

  • Fundamentals of Biologicals Regulation

    Vaccines and Biotechnology Medicines
    • 2nd Edition
    • Rebecca Sheets + 6 more
    • English
    This second edition of Fundamentals of Biologicals Regulation: Vaccines and Biotechnology Medicines serves as an introduction to the international regulatory arena in which biologicals are developed and offers an overview of the processes and insight into the scientific concepts underpinning global regulations. In this new edition the book provides more in-depth coverage of Quality by Design, Combination Products, Quality Target Product Profiles, Risk Management Plans and REMS, and switching from reliance on in vivo to in vitro analytical methods. This new edition also reflects the new developments and processes accelerated by the COVID-19 vaccine experience, including emergency use authorizations and conditional marking authorizations. New pedagogic elements and case studies have been added to improve learning outcomes for students. This book provides multiple levels of readership with guidance on basic concepts, a detailed look at regulatory challenges, and practical insight into how regulators consider regulatory science and regulatory process issues across various regions with emphasis on the European Medicines Agency and the U.S. Food and Drug Administration. Graduate students will benefit from the new pedagogic features. Regulatory professionals will have in Fundamentals of Biologicals Regulation: Vaccines and Biotechnology Medicines a complete guide to navigate through the approval process.

  • Artificial Intelligence in Precision Drug Design, Volume 2

    Advanced Applications
    • 1st Edition
    • Khalid Raza
    • English
    Artificial Intelligence in Precision Drug Design, Volume 2: Advanced Applications explores the transformative role of AI in modern drug discovery and development, presenting cutting-edge research and methodologies that integrate machine learning, network pharmacology, and computational modeling to accelerate therapeutic innovation. It covers a wide range of applications, including AI-driven drug repurposing, combination therapies, cancer immunotherapy, neuroscience, vaccine development, and molecular dynamics, but also delves into emerging technologies such as quantum computing, large language models, and graph neural networks. Designed for academics, this volume provides researchers, clinicians, and graduate students with a resource on the latest AI methodologies in precision medicine.Users will find this to be a great resource that supports evidence-based innovation, fosters interdisciplinary collaboration, and equips them with insights to advance personalized healthcare solutions.

  • Artificial Intelligence in Precision Drug Design, Volume 1

    Foundations and Core Techniques
    • 1st Edition
    • Khalid Raza
    • English
    Artificial Intelligence in Precision Drug Design: Advanced Applications showcases how artificial intelligence (AI) is revolutionizing modern drug discovery and development. Building upon the foundational principles established in Volume 1, this book dives into real-world applications where AI accelerates innovation, enhances predictive accuracy, and enables breakthrough therapeutics. Featuring contributions from leading global researchers and practitioners, the book explores machine learning, deep learning, and network-based approaches applied to complex biomedical challenges. Key areas include AI driven drug repurposing, combination therapies, immunotherapy, vaccine design, quantum computing, and the integration of large language models in drug discovery. Additional chapters highlight predictive modeling using electronic health records, AI-powered medical imaging, and explainable AI for structure-based drug design. What sets this volume apart is its emphasis on practical impact, demonstrating how data, computation, and interdisciplinary collaboration converge to advance precision medicine. Designed for scientists, clinicians, educators, and students, it serves as both a comprehensive reference and a source of inspiration for leveraging AI to transform healthcare.

  • Lipid Nanoparticles-Based mRNA Delivery System

    • 1st Edition
    • Raj Kumar
    • English
    Lipid Nanoparticles-Based mRNA Delivery System offers a comprehensive exploration of lipid nanoparticles (LNPs), the most promising delivery vehicles for mRNA. The book consolidates current knowledge, identifies research gaps, and provides insights into the latest developments in LNP technologies, making it an essential resource for researchers, pharmaceutical developers, and clinicians at the forefront of mRNA therapeutics. Exploring the intricacies of LNP formulation, the book covers a wide range of topics, including the fundamental principles of lipid nanoparticles, design strategies for effective mRNA encapsulation, and the unique challenges associated with various routes of administration—such as intravenous, oral, transdermal, and intranasal delivery.The book also examines the therapeutic applications of lipid-based systems, particularly in vaccines and cancer immunotherapy, while addressing critical challenges like immunogenicity and regulatory considerations. Final sections provide a forward-looking perspective on future trends and innovations in lipid-based mRNA delivery systems, ensuring that readers are well-equipped to navigate this rapidly evolving field.

  • Nanotechnology-Based Innovations in Chronic Obstructive Pulmonary Disease (COPD) Treatment and Management

    • 1st Edition
    • Harish Dureja + 5 more
    • English
    Nanotechnology-Based Innovations in Chronic Obstructive Pulmonary Disease (COPD) Treatment and Management explores innovative drug delivery systems utilizing nanotechnology to revolutionize the treatment and management of COPD. By presenting the latest advancements in nanotechnologies—inc... polymeric nanoparticles, liposomes, and theranostic nanoparticles—this volume aims to enhance patient outcomes, alleviate symptoms, and improve lung function, thereby addressing the urgent need for more effective therapies. Structured to cater to a diverse audience, from beginners to advanced researchers, this comprehensive text begins with an overview of COPD, its epidemiology, and current limitations in treatment. The core chapters explore a wide range of nanotechnological applications for diagnosis and disease management, including cutting-edge topics such as nano-immunotherapy and green nanotechnology. Each chapter was developed by a multidisciplinary team of experts from academia and industry, ensuring a comprehensive approach that integrates insights from pharmaceutical sciences, respiratory health, and bioinformatics. Nanotechnology-based Innovations in Chronic Obstructive Pulmonary Disease (COPD) Treatment and Management not only fills a critical gap in COPD literature but also serves as an invaluable resource for researchers, clinicians, and students alike. It promises to be a definitive guide on how innovative drug delivery systems can transform COPD care, paving the way for future advancements in respiratory health management.

  • Antibiotic Resistance and Nanotherapy

    • 1st Edition
    • Awanish Kumar + 1 more
    • English
    Antibiotic Resistance and Nanotherapy is a comprehensive guide that explores an interdisciplinary approach to address the pressing issue of antibiotic resistance and explores the possibility of nanotherapy as a cutting-edge strategy to treat illnesses that are resistant to antibiotics, employing nanoparticles to target and kill bacteria selectively without damaging healthy cells. It details the underlying mechanisms of drug resistance in intracellular and extracellular pathogens and explores the latest advancements in nanotechnology, including the development of innovative nanomaterials and delivery systems that can be utilized to combat antibiotic-resistant infections. This book also discusses the ethical and practical challenges associated with implementing nanotherapy for bacterial resistance. Featuring contributions from experts in the field, this book is an essential resource for researchers, medical professionals, and policymakers seeking to understand and tackle the immediate threat posed by antibiotic resistance.

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