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Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

  • Adenosine in the Nervous System

    • 1st Edition
    • Richard E. Stone
    • English
    This volume in a series on neuroscience provides an overview of the last 20 years of research into the biochemistry, physiology,pharmacol... and clinical therapeutic potential of adenosine and its analogues in the nervous system. Among the topics covered are adenosine transport in nervous systemtissues, adenosine production and metabolism and the electropharmacology of adenosine.

  • Intracellular Messengers

    • 1st Edition
    • C.M. Taylor
    • English
    This important new reference work offers an outstanding collection of articles devoted to the discussion of "intracellular messengers". Extracellular stimuli ("first messengers") bind to receptors on the plasma membrane of cells to trigger changes in the concentration of intracellular messengers ("second messengers") which leads, in turn, to changes in cellular activity. However, the intracellular activities of so called "third messengers" may also be involved complicating the concept of a rigid sequence of events between receptor and response. The preference for the term "intracellular messengers", and, hence, the title of this volume, recognizes that a complex web of interactions between intercellular messengers determines the concentrations and ultimate effects of each.

  • Lithium and the Cell

    Pharmacology and Biochemistry
    • 1st Edition
    • Nicholas J. Birch
    • English
    This up-to-date compilation addresses the scientific problems of determining a mode of action of lithium and provides a cross-disciplinary perspective. In addition to psychiatrists interested in the therapeutic uses of lithium, it will also be of interest to biochemists using lithium as an inhibitor of phosphoinositide signaling, immunologists studying lymphocytes, and dermatologists studying viral replication in the skin.

  • T-Lymphocyte and Inflammatory Cell Research in Asthma

    • 1st Edition
    • G. Jolles + 2 more
    • English
    It is well established that asthma is an inflammatory disease of the airway mucosa and drugs like inhaled glucocorticoids are now commonly introduced early in therapy. A characteristic feature of this disease is the vast number of eosinophils in airway tissue, although many other migratory and resident inflammatory cells with the capacity to synthesize and release cytokines and putative asthma mediators are present in the inflamed mucosa. The cross-talk between lymphocytes and these cells and the role of cytokines in complex biological networks are currently areas of intense research.This volume gathers together chapters and discussions on the biology of immunocompetent and inflammatory cells, cellular interplay and communication, and on the relative importance of cells and mediators in disease.It should help contribute to further insights into the pathology of asthma and to the development of novel efficacious drugs for the treatment of asthma and related respiratory disorders.

  • Transforming Your STEM Career Through Leadership and Innovation

    Inspiration and Strategies for Women
    • 1st Edition
    • Pamela McCauley Bush
    • English
    Transforming Your STEM Career Through Leadership and Innovation offers valuable information on what it means to be a leader and innovator and encourages you to discover and develop these skills for yourself. This book integrates leadership and innovation principles with personal examples and profiles of inspirational women. By providing a clear process on how to build upon your personal strengths to realize leadership and innovation goals, this book will inspire you to pick up the mantle and meet the critical need for leadership and innovation in the STEM fields. This is a must-have guide that is relevant and valuable for women in all stages of their careers.

  • Lead Compounds from Medicinal Plants for the Treatment of Cancer

    • 1st Edition
    • Christophe Wiart
    • English
    Lead Compounds from Medicinal Plants for the Treatment of Cancer is the first volume in the series, Pharmaceutical Leads from Medicinal Plants. The plant species described in this reference have been carefully selected based on pharmacological evidence and represent today’s most promising sources of natural products for the discovery of anti-cancer drugs. Containing references to primary source material, over a hundred botanical illustrations, a table of chemical structures and much more, this book is an essential starting point for cancer researchers and those involved in anti-cancer drug discovery helping you identify the best novel lead molecules for further anti-cancer drug development.

  • Current Challenges in Personalized Cancer Medicine

    • 1st Edition
    • Volume 65
    • English
    For this volume of Advances in Pharmacology we have brought together some of the foremost basic science and clinical researchers to discuss some of the new frontiers in the development of targeted cancer therapy. Although still in its formative stages, the development of targeted cancer therapies has already shown incredible promise in a limited number of cancer types. As basic cancer research and drug development continues, we expect this number to grow and more patients to benefit from these exciting advances. Through better patient selection and novel strategies to manage resistance, a future can be envisaged in which cancer can be reduced to the level of a chronic, manageable disease.

  • Principles of Clinical Pharmacology

    • 3rd Edition
    • Shiew-Mei Huang + 2 more
    • English
    Principles of Clinical Pharmacology is a successful survey covering the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This essential reference continues to focus on the basics of clinical pharmacology for the development, evaluation, and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the third edition has been thoroughly updated to provide readers with an ideal reference covering the wide range of important topics impacting clinical pharmacology as the discipline plays an increasingly significant role in drug development and regulatory science. The Third Edition has been endorsed by the American Society for Clinical Pharmacology and Therapeutics

  • Practical Biostatistics

    A Friendly Step-by-Step Approach for Evidence-based Medicine
    • 1st Edition
    • Mendel Suchmacher + 1 more
    • English
    Evidence-based medicine aims to apply the best available evidence gained from the scientific method to medical decision making. It is a practice that uses statistical analysis of scientific methods and outcomes to drive further experimentation and diagnosis. The profusion of evidence-based medicine in medical practice and clinical research has produced a need for life scientists and clinical researchers to assimilate biostatistics into their work to meet efficacy and practical standards. Practical Biostatistics provides researchers, medical professionals, and students with a friendly, practical guide to biostatistics. With a detailed outline of implementation steps complemented by a review of important topics, this book can be used as a quick reference or a hands-on guide to effectively incorporate biostatistics in clinical trials.

  • Current State of Alzheimer's Disease Research and Therapeutics

    • 1st Edition
    • Volume 64
    • English
    This new volume of Advances in Pharmacology explores the Current State of Alzheimer's Disease Research and Therapeutics. Chapters cover such topics as the The role heat shock proteins play in the Alzheimer's Theater, Gamma-Secretase as a Target for Alzheimer's Disease, and Identification of protein kinase C for the treatment of dementias. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike.

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